Search results for "INTERACTIONS"
showing 10 items of 1963 documents
Semantics driven interaction using natural language in students tutoring
2007
The aim of this work is to introduce a semantic integration between an ontology and a chatbot in an Intelligent Tutoring Systems (ITS) to interact with students using natural language. The interaction process is driven by the use of a purposely defined ontology. In the ontology two types of conceptual relations are defined. Besides the usual relations, which are used to define the domain's structure, another type of relation is used to define the navigation schema inside the ontology according to the need of managing uncertainty. Uncertainty level is related to student knowledge level about the involved concepts. In this work we propose an ITS for the Java programming language called TutorJ…
Towards a Unified Functional Trait Framework for Parasites
2019
Trait-based research holds high potential to unveil ecological and evolutionary processes. Functional traits are fitness-related characteristics of individuals, which are measured at individual level and defined without using information external to the individual. Despite the usefulness of the functional approach to understand the performance of individuals in ecosystems, and parasitism being the most common life-history strategy on Earth, studies based on functional traits of parasites are still scarce. Since the choice of functional traits is a critical step for any study, we propose a core list of seven functional traits of metazoan parasites, related to three universal challenges faced…
Recombination processes in unintentionally doped GaTe single crystals
2002
Emission spectra of GaTe single crystals in the range of 1.90–1.38 eV have been analyzed at different temperatures and excitation intensities by photoluminescence, photoluminescence excitation, and selective photoluminescence. A decrease in band gap energy with an increase in temperature was obtained from the redshift of the free exciton recombination peak. The energy of longitudinal optical phonons was found to be 14±1 meV. A value of 1.796±0.001 eV for the band gap at 10 K was determined, and the bound exciton energy was found to be 18±0.3 meV. The activation energy of the thermal quenching of the main recombination peaks and of the ones relating to the ionization energy of impurities and…
Particle Physics in High School: A Diagnose Study
2016
Abstract The science learning process improves when the contents are connected to students' lives. Particle physics has had a great impact in our society in the last years and has changed the theoretical picture about matter fundamental dynamics. Thus, we think that academic contents about matter components and interactions should be updated. With this study we aim to characterize the level of knowledge of high school students about this topic. We built a test with questions about classical atomic models, particle physics, recent discoveries, social implications and students opinions about it. Contrary to our first suspicion, students' answers show a high variability. They have new physics …
Viral fitness correlates with the magnitude and direction of the perturbation induced in the host’s transcriptome: the tobacco etch Potyvirus—tobacco…
2018
Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their evolutionary potential. Darwinian fitness, defined as the advantage of a given genotype with respect to a reference one, is a complex property that captures, in a single figure, differences in performance at every stage of viral infection. To what extent does viral fitness result from specific molecular interactions with host factors and regulatory networks during infection? Can we identify host genes in functional classes whose expression depends on viral fitness? Here, we compared the transcriptomes of tobacco plants infected with seven genotypes of tobacco etch potyv…
Tetraspanin CD151 Promotes Initial Events in Human Cytomegalovirus Infection.
2016
ABSTRACT Human cytomegalovirus (HCMV), a betaherpesvirus, can cause life-threatening disease in immunocompromised individuals. Viral envelope glycoproteins that mediate binding to and penetration into target cells have been identified previously. In contrast, cellular proteins supporting HCMV during entry are largely unknown. In order to systematically identify host genes affecting initial steps of HCMV infection, a targeted RNA interference screen of 96 cellular genes was performed in endothelial cells by use of a virus strain expressing the full set of known glycoprotein H and L (gH/gL) complexes. The approach yielded five proviral host factors from different protein families and eight an…
Endoparasites of the blue whiting, Micromesistius poutassou from north-west Spain.
2005
AbstractThe communities of metazoan endoparasites of blue whiting, Micromesistius poutassou, in waters of north-west Spain were analysed and a geographical comparison made with other localities. Four hundred blue whiting collected in July 1999 and September 2000 were examined for parasites, excluding the head and gills. Six species were found: Anisakis simplex s.l. (L3), A. physeteris (L3), Hysterothylacium aduncum (L2 and L3), Stephanostomum lophii (metacercaria), S. pristis (adult), and Prosorhynchus crucibulum (metacercaria). The latter is a new host record, and A. physeteris is reported for the first time in blue whiting from the north-east Atlantic. Host gender was not a significant pr…
Crystal structure of bis[μ-1,4-bis(diphenylphosphanyl)butane-κ2P:P′]bis[(3,4,7,8-tetramethyl-1,10-phenanthroline-κ2N,N′)copper(I)] bis(hexafluoridoph…
2016
The dication of the title compound, [Cu2(C28H28P2)2(C16H16N2)2](PF6)2·2CH2Cl2, has crystallographically imposed inversion symmetry. The copper(I) cation is coordinated in a distorted tetrahedral geometry by two N atoms of a chelating 3,4,7,8-tetramethyl-1,10-phenanthroline ligand and two P atoms of two bridging 1,4-bis(diphenylphosphanyl)butane ligands, forming a 14-membered ring. An intramolecular π–π interaction stabilizes the conformation of the dication. In the crystal, dications are linked by π–π interactions involving adjacent phenanthroline rings, forming chains running parallel to [111]. Weak C—H...F hydrogen interactions are also observed.
Polarization angle dependence of the breathing modes in confined one-dimensional dipolar bosons
2021
Probing the radial collective oscillation of a trapped quantum system is an accurate experimental tool to investigate interactions and dimensionality effects. We consider a fully polarized quasi-one dimensional dipolar quantum gas of bosonic dysprosium atoms in a parabolic trap at zero temperature. We model the dipolar gas with an effective quasi-one dimensional Hamiltonian in the single-mode approximation, and derive the equation of state using a variational approximation based on the Lieb-Liniger gas Bethe Ansatz wavefunction or perturbation theory. We calculate the breathing mode frequencies while varying polarization angles by a sum-rule approach, and find them in good agreement with re…
Microscopic interactions between ivermectin and key human and viral proteins involved in SARS-CoV-2 infection
2021
The identification of chemical compounds able to bind specific sites of the human/viral proteins involved in the SARS-CoV-2 infection cycle is a prerequisite to design effective antiviral drugs. Here we conduct a molecular dynamics study with the aim to assess the interactions of ivermectin, an antiparasitic drug with broad-spectrum antiviral activity, with the human Angiotensin-Converting Enzyme 2 (ACE2), the viral 3CLpro and PLpro proteases, and the viral SARS Unique Domain (SUD). The drug/target interactions have been characterized in silico by describing the nature of the non-covalent interactions found and by measuring the extent of their time duration along the MD simulation. Results …