Search results for "INTRAC"

showing 10 items of 1509 documents

Molecular Progression in Unusual Recurrent Non-Pediatric Intracranial Clear Cell Meningioma

2017

We report a case of a recurrent clear cell meningioma (CCM) in the frontal lobe of the brain of a 67-year-old man. The patient developed three recurrences: at 3, 10, and 12 years after his initial surgery. Histopathology observations revealed a grade 2 CCM with positivity for vimentin and epithelial membrane antigen. Expression of E-cadherin was positive only in the primary tumour and in the first available recurrence. Fluorescence in situ hybridization analyses demonstrated 1p and 14q deletions within the last recurrence. Multiplex ligation-dependent probe amplification studies revealed a heterozygous partial NF2 gene deletion, which progressed to total loss in the last recurrence. The las…

medicine.medical_specialtyPathologyrecurrenceCase ReportVimentin03 medical and health sciences0302 clinical medicineCDKN2ACDKN2BmedicineClear Cell MeningiomaNeoplasmgeneticstumour suppressor genesbiologymedicine.diagnostic_testbusiness.industryintracranial diseaseClear cell meningiomamedicine.diseaseFrontal lobemolecular progressionNF2030220 oncology & carcinogenesisbiology.proteinHistopathologynon-pediatric diseasebusiness030217 neurology & neurosurgeryFluorescence in situ hybridizationCurrent Oncology
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A survey on current practice in the neurosurgical management of preterm infants with posthemorrhagic hydrocephalus in Germany.

2012

Background and Study Aims  Different approaches to the management of preterm infants with posthemorrhagic hydrocephalus (PHH) are described in the literature. Likewise, neurosurgical and pediatric surgical departments in German hospitals use different methods to treat these patients. The aim of this study was therefore to assess the current situation regarding the management of PHH, which is a first and essential step toward the development of standards of practice. Patients and Methods  In the second half of 2009, we sent standardized questionnaires to 139 neurosurgical departments (number of returned questionnaires: 98) and 73 pediatric surgical departments (returned questionnaires: 62) t…

medicine.medical_specialtyPediatricsNeurosurgeryPediatricsVentriculoperitoneal ShuntNeurosurgical ProceduresVentriculoperitoneal shuntsPosthemorrhagic hydrocephalusGermanySurveys and QuestionnairesPediatric surgeryMedicineInitial treatmentHumansPractice Patterns Physicians'Csf shuntbusiness.industryData CollectionInfant Newbornmedicine.diseasehumanitiesIntraventricular hemorrhageCurrent practicePractice Guidelines as TopicSurgeryNeurology (clinical)NeurosurgerybusinessIntracranial HemorrhagesInfant PrematureHydrocephalusJournal of neurological surgery. Part A, Central European neurosurgery
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Non-invasive Spatial Mapping of Frequencies in Atrial Fibrillation: Correlation With Contact Mapping

2021

[EN] Introduction: Regional differences in activation rates may contribute to the electrical substrates that maintain atrial fibrillation (AF), and estimating them non-invasively may help guide ablation or select anti-arrhythmic medications. We tested whether non-invasive assessment of regional AF rate accurately represents intracardiac recordings. Methods: In 47 patients with AF (27 persistent, age 63 +/- 13 years) we performed 57-lead non-invasive Electrocardiographic Imaging (ECGI) in AF, simultaneously with 64-pole intracardiac signals of both atria. ECGI was reconstructed by Tikhonov regularization. We constructed personalized 3D AF rate distribution maps by Dominant Frequency (DF) ana…

medicine.medical_specialtyPhysiologymedicine.medical_treatmentDriverBasket mapping030204 cardiovascular system & hematologyIntracardiac injectionlcsh:PhysiologyCorrelationTECNOLOGIA ELECTRONICA03 medical and health sciences0302 clinical medicineInternal medicinePhysiology (medical)medicineOriginal ResearchImatges tridimensionals en medicinalcsh:QP1-981Dominant frequencybusiness.industryNon invasiveSpatial mappingElectrocardiographic imagingAtrial fibrillationDominant frequencyAblationmedicine.diseaseAtrial fibrillationElectrocardiographic imagingNon-invasive mappingCardiologyEnginyeria biomèdicabusiness030217 neurology & neurosurgery
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Neurosurgery of Malignant Brain Tumors

1987

To Virchow 167 belongs the credit of identifying as tumors, tissue changes already described in the brain, and at the same time to have published an account of the characteristics of the gliomas and the first classification of the various types. It was only the knowledge of the neoplastic nature of the gliomas 127 which made possible surgical action with the aim of extirpation (Fig. 1), when at the end of the 19th century the stormy development of surgery in other parts of the body was being practised successfully 162. The first reports about the removal of an intracerebral space-occupying lesion came from Wernicke and Hahn (1881)183 and also from Bennett and Godley (1884)16. In both cases …

medicine.medical_specialtyPilocytic astrocytomamedicine.diagnostic_testbusiness.industrymedicine.diseaseFourth ventricleLesionPositron emission tomographyGliomamedicineNeurosurgeryRadiologymedicine.symptombusinessAbscessIntracranial pressure
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High Resolution CT Angiography in Detection of an Aneurysm of the Vein of Galen as a Source of Intracranial Haemorrhage in a Newborn.

2011

Cerebral haemorrhage is a rare condition in infants and carries a known poor prognosis. Common causes of spontaneous haemorrhage include various vascular venous lesions due to incomplete hydrovenous maturation, among them Galen vein aneurysm may be a very rare cause of cerebral haemorrhage. This report emphasizes the role of multidector CT with high resolution CT angiography in a newborn with cerebral hemorrhage caused by Galen vein aneurysm rupture. MDCT with high resolution CT angiography helps to differentiate the cause of haemorrhage, and to address the appropriate treatment.

medicine.medical_specialtyPoor prognosismedicine.diagnostic_testbusiness.industryIntracranial haemorrhageSettore MED/50 - Scienze Tecniche Mediche ApplicateGalen vein aneurysmHigh resolutionGeneral Medicinemedicine.diseaseSurgerySettore MED/38 - Pediatria Generale E Specialisticamedicine.anatomical_structureAneurysmAngiographycardiovascular systemmedicineSpontaneous haemorrhageRadiology Nuclear Medicine and imagingNeurology (clinical)RadiologyMultidetector row CT intracranial haemorrhage vein of Galen aneurysmVeinbusinessThe neuroradiology journal
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Predictors of live birth in women with a history of biochemical pregnancies after assisted reproduction treatment

2020

Abstract Objectives To ascertain whether women with a history of biochemical pregnancies (BPs) in in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatment cycles have decreased chances of live birth (LB); and (2) to build a predictive model for LB in this particular population of infertile women. Methods In order to achieve the first objective, data from 1536 women that had a LB using autologous fresh or frozen embryos, or dropped out of further IVF/ICSI treatments after completing one to three unsuccessful treatment cycles were retrospectively analyzed. A subpopulation of 90 women that experienced one or more BPs in our assisted reproduction unit were selected to buil…

medicine.medical_specialtyPregnancy Ratemedia_common.quotation_subjectmedicine.medical_treatmentPopulationLogistic regressionIntracytoplasmic sperm injection03 medical and health sciences0302 clinical medicineEmbryo cryopreservationPregnancyHumansMedicine030212 general & internal medicineeducationRetrospective Studiesmedia_commoneducation.field_of_study030219 obstetrics & reproductive medicineIn vitro fertilisationbusiness.industryObstetricsObstetrics and GynecologyEmbryo TransferEmbryo transferLogistic ModelsReproductive MedicineCase-Control StudiesFemaleReproductionLive birthbusinessInfertility FemaleLive BirthEuropean Journal of Obstetrics & Gynecology and Reproductive Biology
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Additive effect of factors related to assisted conception on the reduction of maternal serum pregnancy-associated plasma protein A concentrations and…

2013

Objective To analyze whether assisted conceptions need adjustments in first-trimester Down syndrome screening and why modifications in screening markers occur. Design Eleven-year cohort retrospective analysis. Setting Maternal-fetal medicine unit. Patient(s) Two thousand eleven naturally conceived normal singleton pregnancies and 2,042 normal singleton pregnancies achieved with assisted conception: 350 by IUI and 1,692 with IVF (n = 328) or intracytoplasmic sperm injection (ICSI; n=1,364), using nondonor (n = 1,086) or donated ova (n = 606), with fresh (n = 1,432) or frozen (n = 260) embryos. Intervention(s) Comparison of ultrasound and biochemical markers of first-trimester Down syndrome s…

medicine.medical_specialtyPregnancy-associated plasma protein AReproductive Techniques Assistedmedicine.medical_treatmentDown-RegulationFertilization in VitroIntracytoplasmic sperm injectionEmbryo cryopreservationPredictive Value of TestsPregnancyPrenatal DiagnosismedicineHumansPregnancy-Associated Plasma Protein-AChorionic Gonadotropin beta Subunit HumanFalse Positive Reactionsreproductive and urinary physiologyInsemination ArtificialRetrospective StudiesGynecologyDown syndrome screeningAnalysis of VarianceChi-Square DistributionOocyte Donationbusiness.industrySingletonFree βhcgObstetrics and GynecologyPregnancy Trimester FirstReproductive MedicineCohortFemaleHormone therapyDown SyndromebusinessNuchal Translucency MeasurementBiomarkersFertility and sterility
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Validation of the Angioedema Control Test (AECT)—A Patient-Reported Outcome Instrument for Assessing Angioedema Control

2019

Background Recurrent angioedema (RA) is an important clinical problem in routine care and emergency medicine. As of recently, the only validated tools to specifically assess disease status in patients with RA were diary-type activity assessments and angioedema-related quality-of-life questionnaires. Although these tools are particularly helpful in clinical studies, they were not designed to determine disease control or to guide treatment decisions. To close this gap, the Angioedema Control Test (AECT) was published recently. Objective To test the AECT for its validity and reliability, and to identify a cutoff value to aid treatment decisions. Methods Two AECT versions with a recall period o…

medicine.medical_specialtyPsychometricsIntraclass correlationValidity03 medical and health sciences0302 clinical medicineCronbach's alphaSurveys and QuestionnairesmedicineHumansImmunology and AllergyPatient Reported Outcome Measures030212 general & internal medicineAngioedemaAngioedemabusiness.industryReproducibility of ResultsDermatology Life Quality Indexmedicine.disease030228 respiratory systemConvergent validityHereditary angioedemaQuality of LifePhysical therapyPatient-reported outcomemedicine.symptombusinessThe Journal of Allergy and Clinical Immunology: In Practice
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International psychometric validation of the Living with Chronic Illness Scale in Spanish-speaking patients with chronic obstructive pulmonary disease

2021

Objectives To validate the Living with Chronic Illness (LW-CI) Scale in patients with chronic obstructive pulmonary disease (COPD). Design Observational, cross-sectional validation study with retest. Acceptability, reliability, precision and construct validity were tested. Setting The study took place in primary and secondary specialised units of public and private hospitals of Spain and Colombia. Participants The study included 612 patients with COPD assessed from May 2018 to May 2019. A consecutive cases sampling was done. Inclusion criteria included: (A) patients with a diagnosis of COPD; (B) native Spanish speaking; (C) able to read and understand questionnaires; and (D) able to provide…

medicine.medical_specialtyPsychometricsMedicinaIntraclass correlationPopulationNursingColombiaquality in health care03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineCronbach's alphaQuality of lifeInformed consentSurveys and QuestionnairesmedicineChronic airways diseaseHumans030212 general & internal medicine1506educationCOPDeducation.field_of_studybusiness.industryadult pathologyRConstruct validityReproducibility of ResultsGeneral Medicinemedicine.diseaseCross-Sectional Studies030228 respiratory systemSpainchronic airways diseaseChronic DiseasePhysical therapyQuality in health careQuality of LifeAdult pathologyMedicineObservational study1715business
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A rare case of ruptured aneurysm of the paramedian artery of Percheron.

2018

Introduction The artery of Percheron is a rare anatomic variant supplying bilateral medial thalamic nuclei and a variable portion of the rostral part of midbrain. Case report A 48-year-old female with massive subarachnoid hemorrhage due to a ruptured aneurysm of the paramedian artery of Percheron presented to the emergency room. Because of significant risk of recurrent intracranial hemorrhage, it was decided to proceed with endovascular embolization of the aneurysm. The patient was ultimately sent to a rehabilitation center and her presenting neurologic deficits showed significant improvements in the weeks following endovascular embolization treatment. Discussion The paramedian artery of Pe…

medicine.medical_specialtyRadiology Nuclear Medicine and ImagingSubarachnoid hemorrhagemedicine.medical_treatmentAneurysm RupturedArtery of Percheron030218 nuclear medicine & medical imagingArtery of percheron03 medical and health sciences0302 clinical medicineAneurysmThalamusMesencephalonRare casemedicineHumansEmbolizationSignificant riskcardiovascular diseasesArterial anatomybusiness.industryAnatomic VariationIntracranial AneurysmCerebral ArteriesMiddle AgedSubarachnoid Hemorrhagemedicine.diseaseEmbolization TherapeuticAneurysmSurgerymedicine.anatomical_structureruptured cerebral aneurysmFemaleNeurology (clinical)businessCardiology and Cardiovascular Medicine030217 neurology & neurosurgeryArteryInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
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