Search results for "INVESTIGATION"
showing 10 items of 366 documents
Malformations of central nervous system: General issues
2013
Malformations of the central nervous system (CNS) encompass a heterogeneous group of congenital anomalies that may be isolated or appear as part of a genetic syndrome. Advances in identifying the genetic etiology underlying many CNS malformation and syndromes have led to the current genetic-based classifications that allows us to better estimate prognosis and potential complications. Herein, we discuss the main genetic, clinical and radiological features and their implications for diagnostic testing and disease management
Forensic investigation in aircraft accident with the aid of CT (MSCT), and Magnetic Resonance Imaging (MRI): our experience
2011
The autors report their experience in a case of air disaster in which a Tuninter airlines ATR 72 fallen down into the sea near Capo Gallo coast (Palermo, Italy) with 39 persons on board, resulting in six-teen victims. In the present contribute the authors argued the causes of the death and analysed patternes of injuries sustained by passengers involved in the fatal airplane accident using the conventional autopsy combined with postmortem Multi Slice Computed Tomography (MSCT) examination.
‘There should be no open doors in the police’: criminal investigations in northern Ghana as boundary work
2012
ABSTRACTIn criminal investigations by police officers in northern Ghana, the lines are fluid: civilians arrest suspects on their own, assuming the tasks of the police. Police officers are heavily influenced by civilians, often forming paid alliances with them. Yet such entanglements paradoxically enable state policing and integrate the police into society in a context of low resources and low legitimacy. Other practices limit and frame such transgressions. Using the concept of boundary work, this article analyses how actors maintain and negotiate the seemingly blurred distinction between state and society in West Africa.
First data on the taxonomic diversity of the Portulaca oleracea aggregate (Portulacaceae) in Iran
2017
The review of specimens from Iran belonging to the Portulaca oleracea L. aggregate resulted in the recognition of six microspecies: P. cypria Danin, P. granulatostellulata (Poelln.) Ricceri & Arrigoni, P. nitida (Danin & H.G.Baker) Ricceri & Arrigoni, P. rausii Danin, P. socotrana Domina & Raimondo, and P. trituberculata Danin, Domina & Raimondo, all reported for the first time for the flora of Iran. The identification was based on the microscopic study of seeds. It is noted that P. oleracea is not confirmed for Iran. Distribution data and an identification key for Portulaca microspecies in Iran are presented.
Assessing the MALDI-TOF MS sample preparation procedure to analyze the influence of thermo-oxidative ageing and thermo-mechanical degradation on poly…
2011
[EN] Multiple processing by means of successive injection cycles was used to simulate the thermo-mechanical degradation effects on the oligomeric distribution of PLA under mechanical recycling. Likewise, an accelerated thermal ageing over PLA glass transition was performed in order to simulate its service life. MALDI-TOF MS was used for the analysis and the sample preparation procedure was assessed by means of a statistical Design of Experiments (DoE). The quality effects in use for the analysis were signal-to-noise ratio and Resolution. Different matrixes, analyte/matrix proportions and the use of NaTFA as cationization agent were considered. A deep inspection of the statistical results pr…
Targeted therapy for hepatocellular carcinoma: novel agents on the horizon.
2012
Hepatocellular carcinoma (HCC) is the most common liver cancer, accounting for 90% of primary liver cancers. In the last decade it has become one of the most frequently occurring tumors worldwide and is also considered to be the most lethal of the cancer systems, accounting for approximately one third of all malignancies. Although the clinical diagnosis and management of early-stage HCC has improved significantly, HCC prognosis is still extremely poor. Furthermore, advanced HCC is a highly aggressive tumor with a poor or no response to common therapies. Therefore, new effective and well-tolerated therapy strategies are urgently needed. Targeted therapies have entered the field of anti-neopl…
Conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting tyrosine kinase inhibitor-based therapy
2015
Abstract: Introduction: Angiogenesis is fundamental for tumor development and progression. Hence, anti-angiogenic drugs have been developed to target VEGF and its receptors (VEGFRs). Several tyrosine kinase inhibitors (TKIs) have been developed over the years and others are still under investigation, each anti-VEGFR TKI showing a different cardiotoxic profile. Knowledge of the cardiac side-effects of each drug and the magnitude of their expression and frequency can lead to a specific approach. Areas covered: This work reviews the mechanism of action of anti-VEGFR TKIs and the pathophysiological mechanisms leading to cardiotoxicity, followed by close examination of the most important drugs i…
La Valle dei Templi in epoca medioevale. Caratterizzazione antropologica e paleopatologica delle sepolture antistanti in Tempio della Concordia
2021
Riassunto ― Il lavoro presenta i risultati delle analisi bio-archeologiche effettuate su resti scheletrici umani rinvenuti in quattordici sepolture di epoca medioevale rinvenute nel Parco Archeologico della Valle dei Templi di Agrigento (Sicilia). L’obiettivo è stato l’acquisizione delle informazioni necessarie per la ricostruzione del profilo biologico di ciascun individuo, al fine di determinarne il sesso, la stima dell’età biologica alla morte, la stima della statura e la valutazione delle patologie e degli indicatori di stress occupazionale mediante le correnti metodologie e tecniche diagnostiche di tipo antropologico. Sebbene il cattivo stato di conservazione di alcuni individui non ne…
Application of Thermographic Techniques for the Detection of Failures on Photovoltaic Modules
2019
The paper focuses on thermography as a useful investigation tool for diagnosis, detection and prevention of failures of photovoltaic modules. The paper describes the faults detectable by thermographic investigations and how to conduct these investigantions. Then the results of some analyses conducted on a photovoltaic field are presented. The investigations made possible to identify faulty modules with hot spots by measuring localized superheat due to the presence of concentrated deposits on the exposed surface of the module and the superheating due to the presence of sand/dust deposits distributed on a significant portion of the module surface. The thermographic investigations can be used …