Assessing the MALDI-TOF MS sample preparation procedure to analyze the influence of thermo-oxidative ageing and thermo-mechanical degradation on poly (Lactide)

6533b832fe1ef96bd129ad9e

RESEARCH PRODUCT

Assessing the MALDI-TOF MS sample preparation procedure to analyze the influence of thermo-oxidative ageing and thermo-mechanical degradation on poly (Lactide)

Amparo Ribes-greus Emma Strömberg Sigbritt Karlsson José David Badia

subject

Solucions polimèriques Polymers and Plastics General Physics and Astronomy Transesterifications Thermo-mechanical degradation Sample preparation procedure Matrix (chemical analysis)Degradation Mechanisms Materials Chemistry Cationization Mechanical recycling Sample preparation Repeating unit Poly(lactide)Signal to noise ratio Chemistry Multiple processing Design of Experiments (DoE)Analytes Injection cycles Polylactides MAQUINAS Y MOTORES TERMICOS Matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry Glass transition Design of experiments Glass lasers Thermo mechanical MALDI TOF MS Chromatography Matrix Mass spectrometry Signal to noise Termoplàstics Organic Chemistry Degradation mechanism Thermo-oxidative ageing Statistical design of experiments Matrix-assisted laser desorption/ionization Investigation methods Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)Polylactide (PLA)Ageing Oligomers Degradation (geology)Desorption Deep inspection Experiments Poly(lactide)

description

[EN] Multiple processing by means of successive injection cycles was used to simulate the thermo-mechanical degradation effects on the oligomeric distribution of PLA under mechanical recycling. Likewise, an accelerated thermal ageing over PLA glass transition was performed in order to simulate its service life. MALDI-TOF MS was used for the analysis and the sample preparation procedure was assessed by means of a statistical Design of Experiments (DoE). The quality effects in use for the analysis were signal-to-noise ratio and Resolution. Different matrixes, analyte/matrix proportions and the use of NaTFA as cationization agent were considered. A deep inspection of the statistical results provided a better understanding of the influence of the different factors, individually or in combination, to the signal. The application of DoE for the improvement of the MALDI measurement of PLA stated that the best combination of factors (levels) was the following: matrix (s-DHB), proportion analyte/matrix (1/5 V/V), and no use of cationization agent. Degradation primarily affected the initially predominant cyclic [LA C] n and linear H[LA L] nOH species, where LA stands for a PLA repeating unit. Intramolecular and intermolecular transesterifications as well as hydrolytic and homolytic reactions took place during the formation and disappearance of oligomeric species. In both degradation mechanisms induced by thermal ageing and thermo-mechanical degradation, the formation of H[LA L] nOCH 3 by intermolecular transesterifications was highlighted. © 2011 Elsevier Ltd. All rights reserved.

year	journal	country	edition	language
2011-07-01	European Polymer Journal

https://doi.org/10.1016/j.eurpolymj.2011.05.001