Search results for "IONT"
showing 10 items of 382 documents
Enabling Retransmissions for Achieving Reliable Multicast Communications in WSNs
2016
To ensure end-to-end reliable multicast or broadcast transmissions in IEEE 802.15.4 based wireless sensor networks WSNs) is a challenging task since no retransmission and acknowledgment mechanisms are defined in such WSNs. In this paper, we propose three retransmission enabled multicast transmission schemes in order to achieve reliable packet transmissions in such networks. Different from the legacy CSMA/CA principle, these schemes allow a sending or forwarding node to retransmit a packet if necessary and enable implicit or/and explicit acknowledgment for multicast services. Simulations are performed in order to assess the performance of these schemes in terms of number of retransmissions, …
Multicast delivery of file download services in 3G mobile networks with MBMS
2008
This article investigates the efficient transmission of file download services to several users simultaneously in 3G mobile networks with HSDPA (High-Speed Downlink Packet Access) and MBMS (Multimedia Broadcast Multicast Services). HSDPA supports high speed point-to-point (p-t-p) transmissions (up to several Mb/s), whereas with MBMS the same content can be transmitted with a point-to-multipoint (p-t-m) connection to multiple users in a unidirectional fashion. Multicast delivery can be implemented through only p-t-p transmissions with HSDPA, a single p-t-m transmission with MBMS, or using both jointly in a hybrid approach by employing HSDPA for error repair of the MBMS p-t-m transmission. We…
The Root Mycobiota of Betula aetnensis Raf., an Endemic Tree Species Colonizing the Lavas of Mt. Etna (Italy)
2021
Betula aetnensis is an endemic tree of high conservation value, which thrives on the nutrient-poor volcanic soils of Mount Etna. Since plant–microbe interactions could play a crucial role in plant growth, resource uptake, and resistance to abiotic stresses, we aimed to characterize the root and rhizosphere microbial communities. Individuals from natural habitat (NAT) and forest nursery (NURS) were surveyed through microscopy observations and molecular tools: bacterial and fungal automated ribosomal intergenic spacer analysis (ARISA), fungal denaturing gradient gel electrophoresis (DGGE). B. aetnensis was found to be simultaneously colonized by arbuscular (AM), ectomycorrhizal (ECM), ericoid…
Diffusion of naltrexone across reconstituted human oral epithelium and histomorphological features
2006
Abstract In transbuccal absorption a major limitation could be the low permeability of the mucosa which implies low drug bioavailability. The ability of naltrexone hydrochloride (NLX) to penetrate a resembling histologically human buccal mucosa was assessed and the occurrence of any histomorphological changes observed. We used reconstituted human oral (RHO) non-keratinised epithelium as mucosal section and a Transwell diffusion cells system as bicompartmental model. Buccal permeation was expressed in terms of drug flux ( J s ) and permeability coefficients ( K p ). Data were collected using both artificial and natural human saliva. The main finding was that RHO does not restrain NLX permeat…
Bioavailability in vivo of naltrexone following transbuccal administration by an electronically-controlled intraoral device: a trial on pigs.
2010
Naltrexone (NLX), an opioid antagonist, is widely used in the treatment of opiate addiction, alcoholism and smoking cessation. Its current peroral administration induces various adverse side effects and has limited efficacy since bioavailability and patient compliance are poor. The development of a long-acting drug delivery system of NLX may overcome the current drawbacks and help in the improvement of treatment of addiction. The primary endpoints of this study were: a) to compare the NLX bioavailability and pharmacokinetics after delivering a single transbuccal dose, released by a prototype of intraoral device, versus an intravenous (I.V.) bolus of the same drug dose; b) to verify the func…
Release of naltrexone on buccal mucosa: Permeation studies, histological aspects and matrix system design
2007
Transbuccal drug delivery has got several well-known advantages especially with respect to peroral way. Since a major limitation in buccal drug delivery could be the low permeability of the epithelium, the aptitude of NLX to penetrate the mucosal barrier was assessed. Ex vivo permeation across porcine buccal mucosa 800 microm thick was investigated using Franz type diffusion cells and compared with in vitro data previously obtained by reconstituted human oral epithelium 100 microm thick. Both fluxes (Js) and permeability coefficients (K(p)) are in accordance, using either buffer solution simulating saliva or natural human saliva. Permeation was evaluated also in presence of chemical enhance…
Effects of iontophoretic 5-hydroxytryptamine on the unitary discharge frequency of caudate nucleus neurons in the rat
1980
AbstractSummaryMicroiontophoretic application of 5-hydroxytryptamine (5-HT) on rat caudate nucleus neurons has both facilitatory and inhibitory effects on the discharge frequency of the neurons; in many cases 5-HT has a two-phase action. An analysis was made of the behaviour of facilitatory and inhibitory responses in time considering the mean firing rate variations during and after 5-HT iontophoretic release. Six types of responses have been described : A : short lasting excitation, B : long lasting excitation, C : short lasting inhibition, D : delayed-onset inhibition, E : inhibition followed by excitation, F : excitation followed by inhibition. Also no topographic localization could be m…
NITRIC OXIDE-ACTIVE COMPOUNDS MODULATE IN VIVO GABA-EVOKED RESPONSES IN THE GLOBUS PALLIDUS OF RAT
2012
Nitric oxide (NO) acts as a messenger in the central nervous system; it affects the synaptic activity by modulating neurotransmitter release and/or receptor function. We previously observed that NO-active compounds modify the bioelectric activity of basal ganglia (BG) units. In this study, we applied microiontophoresis to extracellular in vivo recordings to investigate the effect of NO-active compounds on GABA-evoked responses in the globus pallidus (GP) of rats. The response to GABA release was tested on recorded GP neurons before and during the administration of S-nitroso-glutathione (SNOG, NO donor) and/or Nω-nitro-L-arginine methyl ester (L-NAME), inhibitor of nitric oxide synthase (NOS…
Comparative Genomics of Blattabacterium cuenoti: The Frozen Legacy of an Ancient Endosymbiont Genome
2013
Many insect species have established long-term symbiotic relationships with intracellular bacteria. Symbiosis with bacteria has provided insects with novel ecological capabilities, which have allowed them colonize previously unexplored niches. Despite its importance to the understanding of the emergence of biological complexity, the evolution of symbiotic relationships remains hitherto a mystery in evolutionary biology. In this study, we contribute to the investigation of the evolutionary leaps enabled by mutualistic symbioses by sequencing the genome of Blattabacterium cuenoti, primary endosymbiont of the omnivorous cockroach Blatta orientalis, and one of the most ancient symbiotic associa…
Mutual-information based rate-adaptation for Multi-User TH-IR-UWB coded system
2011
In this paper we present a coding rate adaptation technique for a Time-Hopping Impulse-Radio Ultra-Wide Band (TH-IR-UWB) system assuming that the Multi-User Interference (MUI) is modeled as an additive interference noise following a Generalized Gaussian Distribution (GGD). The shape parameter induced by the GGD model is in general time-variant since it strongly depends on the essential UWB system parameters and the received signal power of the active users. In this paper, we show that the performance of a TH-IR-UWB LDPC coded system is quite independent of the GGD shape parameter when we consider the mutual information between the soft input to the decoder and the transmitted sequence, espe…