Search results for "IPR"
showing 10 items of 1515 documents
Chemical constituents and antiproliferative activity of Euphorbia bivonae
2011
Euphorbia is a genus of plants belonging to the family Euphorbiaceae, consisting of about 2160 species. This family occurs mainly in the Indo-Malayan region and tropical America. Euphorbia also has many species in non-tropical areas such as the Mediterranean area, the Middle East, South Africa, and southern USA. Phytochemical studies of species from the genus Euphorbia report the presence of skin-irritating and tumor-promoting diterpenoids, several macrocyclic diterpenoids with antibacterial, anticancer, PGE2-inhibitory, antifeedant, anti-HIV, and analgesic activities. Some of the Euphorbiaceae species are used in folk medicine for the treatment of skin diseases, gonorrhea, migraines, intes…
The European Unemployment Benefit Scheme: Legal Basis for Resocialising Europe
2017
Il presente lavoro analizza la possibile introduzione di un Sussidio europeo di disoccupazione (d’ora in poi EUBS) nella temperie economico-culturale della crisi quale strumento tecnico-giuridico per la risocializzazione dell’Europa. Dopo un’analisi del sistema statunitense di tutela della disoccupazione, che rappresenterebbe un idealtipo in ragione del sistema di competenze condivise tra livello federale e statale, il saggio si concentra sulla legittimità dell’EUBS alla luce dei trattati UE: nonostante l’assenza di un’autonoma potestas normativa europea in materia di sicurezza sociale, l’EUBS potrebbe essere giustificato da un’interpretazione olistica del diritto dell’Unione. Da ultimo, pe…
The interplay of reciprocity propensity and inequality aversion in two-person games
2020
Economic normative models assume that economic actors are fully rational and selfish while recent studies acknowledge the emotional influence of an economic decision and call for further investigation of biases in decision making. Most decisions involve multiple actors who make decisions following a sequential path as reflected by decision trees; this contingency makes a call for the game theory contribution in the economic decision field. Two-person games are widely used to represent a typical framework of economic decisions. This study aims at further investigating psychological biases affecting decisions in a two-person sequential game. So far similar studies have focused on the principa…
Experimental and Numerical Analysis of Microstructure Evolution during Linear Friction Welding of Ti6Al4V
2015
Abstract Linear Friction Welding (LFW) is a solid state welding process used to joint bulk components. In the paper, an experimental and numerical study on LFW of Ti6Al4V titanium alloy is presented. A laboratory designed LFW machine has been used to weld the specimens with different contact pressure and oscillation frequency. The joint microstructure has been experimentally observed with SEM and EDS. A dedicated numerical model, able to predict temperature, strain and strain rate distribution as well as the phase volume fraction evolution, has been utilized to predict the final microstructure in the welded parts. It was found that complete transformation of the alpha phase into beta phase …
Numerical modelling of the linear friction welding process
2010
Linear friction welding (LFW) is a solid-state joining process applied to non-axisymmetric components. LFW involves joining of materials through the relative reciprocating motion of two components under an axial force. In such process the heat source is given by the frictional forces work decaying into heat determining a local softening of the material and proper bonding conditions due to both the temperature increase and the local pressure of the two edges to be welded. In the present work the authors present a numerical model of the linear friction welding process of AISI 1045 parts. The numerical model allowed to highlight the process mechanics and the physical conditions which must be r…
Combination of the top-quark mass measurements from the Tevatron collider
2012
Aaltonen, T. et al.
Higgs boson studies at the Tevatron
2013
We combine searches by the CDF and D0 Collaborations for the standard model Higgs boson with mass in the range 90-200 GeV/c2 produced in the gluon-gluon fusion, WH, ZH, tt̄H, and vector boson fusion processes, and decaying in the H→bb̄, H→W+W-, H→ZZ, H→τ+τ-, and H→γγ modes. The data correspond to integrated luminosities of up to 10 fb-1 and were collected at the Fermilab Tevatron in pp̄ collisions at √s=1.96 TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140 GeV/c2. The local significance corresponds to 3.0 standard deviations at mH=125 GeV/c2, consistent with the…
Evidence for a Particle Produced in Association with Weak Bosons and Decaying to a Bottom-Antibottom Quark Pair in Higgs Boson Searches at the Tevatr…
2012
Aaltonen, T. et al.
A History of the Pharmacological Treatment of Bipolar Disorder.
2018
In this paper, the authors review the history of the pharmacological treatment of bipolar disorder, from the first nonspecific sedative agents introduced in the 19th and early 20th century, such as solanaceae alkaloids, bromides and barbiturates, to John Cade’s experiments with lithium and the beginning of the so-called “Psychopharmacological Revolution” in the 1950s. We also describe the clinical studies and development processes, enabling the therapeutic introduction of pharmacological agents currently available for the treatment of bipolar disorder in its different phases and manifestations. Those drugs include lithium salts, valproic acid, carbamazepine, new antiepilep…
Poliprenolu iedarbība un to ietekme uz atorvastatīna efektiem WISTAR līnijas žurkām uzvedības, atmiņas un analgēzijas testos
2015
Poliprenoli (PP) ir izdalīti no augiem, tai skaitā, no skujkokiem. To ietekme uz centrālās nervu sistēmas (CNS) procesiem ir ļoti maz pētīta. Ir zināms, ka gan PP, gan holesterols un doliholi veidojas caur mevalonskābes atkarīgiem ceļiem (MVA) ar 3-hidroksi-3-metilglutaril-koenzīma A reduktāzes palīdzību. Šo enzīmu inhibē holesterola biosintēzes inhibītori statīni, kuru ilgstoša lietošana slimniekiem nelabvēlīgi ietekmē kognitīvās funkcijas (Schilling et al., 2014). Darba mērķis bija noteikt PP, atorvastatīna (AT), kā arī to kombinācijas ietekmi uz izmēģinājuma dzīvnieku (žurku) vispārējo aktivitāti, atmiņas procesiem un sāpju slieksni. Iegūtie dati liecina, ka AT piemīt pretsāpju iedarbība…