Search results for "IPR"

showing 10 items of 1515 documents

Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review

2017

Marco Solmi,1,2 Andrea Murru,3 Isabella Pacchiarotti,3 Juan Undurraga,4,5 Nicola Veronese,2,6 Michele Fornaro,7,8 Brendon Stubbs,2,9–11 Francesco Monaco,2 Eduard Vieta,3 Mary V Seeman,12 Christoph U Correll,13,14 André F Carvalho2,15 1Neuroscience Department, University of Padua, 2Institute for Clinical Research and Education in Medicine, Padua, Italy; 3Bipolar Disorders Unit, Institute of Neuroscience, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain; 4Department of Psychiatry, Faculty of Medicine, Clínica Alemana Universidad del Desarrollo, 5Early Intervention Program, J. Horwitz Psychiatric Institute, Santiago, Chile; 6Na…

Olanzapinesafetymedicine.medical_specialtyside effectToxicology and Pharmaceutics (all)ReviewRM1-950psychosi03 medical and health sciencesIloperidonechemistry.chemical_compound0302 clinical medicineSertindoleJournal ArticlemedicineAsenapinePharmacology (medical)psychosisGeneral Pharmacology Toxicology and PharmaceuticstolerabilityPsychiatryLurasidoneBrexpiprazolePharmacologyChemical Health and Safetybusiness.industryMedicine (all)Transtornos PsicóticosGeneral Medicinepsychiatry3. Good health030227 psychiatryantipsychotics side effects tolerability safety psychosis psychiatryantipsychoticantipsychoticsside effectsPsychotic DisordersTolerabilitychemistryQuetiapineAntipsychotics; Psychiatry; Psychosis; Safety; Side effects; Tolerability; Medicine (all); Safety Research; Pharmacology Toxicology and Pharmaceutics (all); Chemical Health and Safety; Pharmacology (medical)Therapeutics. PharmacologyAntipsicóticosbusinessSafety Research030217 neurology & neurosurgeryAntipsychotic Agentsmedicine.drugTherapeutics and Clinical Risk Management
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Alcune riflessioni sul dono di ospitalità (xenía) nella Grecia antica

2014

OmeroSettore L-ANT/02 - Storia Grecaospitalitàreciprocità M. MauDonoErodoto
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Clinical Approach to Vascular Calcification in Patients With Non-dialysis Dependent Chronic Kidney Disease: Mineral-Bone Disorder-Related Aspects

2021

Chronic kidney disease (CKD) is associated with a very high morbimortality, mainly from cardiovascular origin, and CKD is currently considered in the high- or very high risk- cardiovascular risk category. CKD-mineral and bone disorders (CKD-MBDs), including vascular and/or valvular calcifications, are also associated with these poor outcomes. Vascular calcification (VC) is very prevalent (both intimal and medial), even in non-dialysis dependent patients, with a greater severity and more rapid progression. Simple X-ray based-scores such as Adragão's (AS) are useful prognostic tools and AS (even AS based on hand-X-ray only) may be superior to the classic Kauppila's score when evaluating non-d…

OncologyMedicine (General)medicine.medical_specialtyMini Review030232 urology & nephrologyParathyroid hormonePhosphate030204 cardiovascular system & hematologyCalcificationcalcification03 medical and health sciencesR5-9200302 clinical medicineInternal medicineVitamin D and neurologymedicineCKDCKD-MBDVascular calcificationphosphateVascular calcificationCalciprotein particlesSurrogate endpointbusiness.industryIncidence (epidemiology)General Medicinemedicine.diseasePathophysiologyvascular calcificationInsuficiència renal crònicaMedicinecalciprotein particlesbusinessCalcificationKidney diseaseFrontiers in Medicine
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Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

2014

// Nicole M. Davis 1 , Melissa Sokolosky 1 , Kristin Stadelman 1 , Stephen L. Abrams 1 , Massimo Libra 2 , Saverio Candido 2 , Ferdinando Nicoletti 2 , Jerry Polesel 3 , Roberta Maestro 4 , Antonino D’Assoro 5 , Lyudmyla Drobot 6 , Dariusz Rakus 7 , Agnieszka Gizak 7 , Piotr Laidler 8 , Joanna Dulinska-Litewka 8 , Joerg Basecke 9 , Sanja Mijatovic 10 , Danijela Maksimovic-Ivanic 10 , Giuseppe Montalto 11,12 , Melchiorre Cervello 12 , Timothy L. Fitzgerald 13 , Zoya N. Demidenko 14 , Alberto M. Martelli 15 , Lucio Cocco 15 , Linda S. Steelman 1 and James A. McCubrey 1 1 Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University Greenville, NC 27858 USA 2 …

Oncologymedicine.medical_specialtytherapy resistanceClass I Phosphatidylinositol 3-Kinasesmedicine.medical_treatmentBreast NeoplasmsReviewBiologyMechanistic Target of Rapamycin Complex 1PI3KMetastasisTargeted therapyPhosphatidylinositol 3-KinasesBreast cancerTARGETED THERAPYInternal medicinemedicinePTENHumansTargeted Therapy Therapy Resistance Mutations PI3K mTOR rapamycinskin and connective tissue diseasesProtein kinase BneoplasmsPI3K/AKT/mTOR pathwayRoswell Park Cancer InstituterapamycinTOR Serine-Threonine KinasesMTORPTEN PhosphohydrolaseCancerTargeted TherapyTherapy Resistancemedicine.diseaseTargeted Therapy; Therapy Resistance; Mutations; PI3K; mTOR; rapamycin3. Good healthErbB ReceptorsGene Expression Regulation NeoplasticOncologyMultiprotein ComplexesCancer researchbiology.proteinFemaleReceptor Epidermal Growth FactormutationRAPAMYCINProto-Oncogene Proteins c-aktMutationsSignal Transduction
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Precision spectroscopy at heavy ion ring accelerator SIS300

2007

Unique spectroscopic possibilities open up if a laser beam interacts with relativistic lithium-like ions stored in the heavy ion ring accelerator SIS300 at the future Facility for Antiproton and Ion Research FAIR in Darmstadt, Germany. At a relativistic factor gamma = 36 the 2P 1/2 level can be excited from the 2S 1/2 ground state for any element with frequency doubled dye-lasers in collinear geometry. Precise transition energy measurements can be performed if the fluorescence photons, boosted in forward direction into the X-ray region, are energetically analyzed with a single crystal monochromator. The hyperfine structure can be investigated at the 2P 1/2 - 2S 1/2 transition for all elemen…

Optical pumpingPhysicsPhotonLaser coolingExcited stateFacility for Antiproton and Ion ResearchAtomic physicsGround stateHyperfine structureIon
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Moderating effects of appreciation on relationships between illegitimate tasks and intrinsic motivation: a two-wave shortitudinal study

2020

This study investigated possible reciprocal relationships between illegitimate tasks and intrinsic motivation and whether appreciation moderated these relationships. Based on a two-wave panel study...

Organizational Behavior and Human Resource Management0502 economics and business05 social sciencesIntrinsic motivation050109 social psychology0501 psychology and cognitive sciencesPsychology050203 business & managementApplied PsychologyReciprocalCognitive psychologyEuropean Journal of Work and Organizational Psychology
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Media coverage about organisations in critical situations – Analysing the impact on employees.

2013

Purpose– This research aims to investigate how critical media coverage of an organisation affects its employees. The authors expect the effects to be similar to the way media coverage about an individual would affect this person, termed “reciprocal effects”.Design/methodology/approach– Drawing on a framework for the analysis of reciprocal effects of mass media by Kepplinger and qualitative interviews among employees of 14 different organisations undergoing a crisis, the authors develop an employee-model of reciprocal effects for the context of organisational crises.Findings– This qualitative research shows that employees are affected by media coverage on a critical issue about their employe…

Organizational Behavior and Human Resource ManagementCoping (psychology)business.industrymedia_common.quotation_subjectShameMedia coverageLearned helplessnessInterpersonal communicationPublic relationsIndustrial relationsSociologybusinessSocial psychologyReciprocalmedia_commonQualitative researchMass media
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Hold up and intergenerational transmission of preferences

2004

This paper focuses on the formation, evolution and stability of the distribution of preferences in the population and its relationship with the investment and bargaining strategies in a simplified hold up problem. More precisely, in our model a population of infinitely-lived players (say, for example, firms) with homogeneous selfish or self-regarding preferences is pair-wise matched at each period with a population of an equal size of short-lived players (say, for example, workers) with heterogeneous preferences. Both types of player play a two-stage game. In the first stage, they decide separately but simultaneously whether to make a general or a relation-specific investment. The latter ty…

Organizational Behavior and Human Resource ManagementEconomics and Econometricseducation.field_of_studyStylized factPopulationComputingMilieux_PERSONALCOMPUTINGInvestment (macroeconomics)Social preferencesMicroeconomicsBargaining powerEconomicsReciprocal altruismHold-up problemeducationInequity aversionJournal of Economic Behavior & Organization
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Komparativno istraživanje oblikovanja četiriju rotirajućih sustava

2015

Svrha: U ovom istraživanju analizirali smo rezno područje, vrijeme instrumentacije, održavanje anatomije korijenskog kanala i neinstrumentirana područja dobivena korištenjem instrumenata F360®, Mtwo®, RaCe® i Hyflex® u ISO veličini 35. Materijali i metode: Odabrano je 120 zuba s jednim ravnim kanalom i podijeljeni su u četiri grupe. Radna duljina određena je radiološki. Zubi su rezani dijamantnim diskom, a presjeci su promatrani stereoskopskim mikroskopom Nikon SMZ-2T pod svjetiljkom Intralux 4000-1. Grupe su oblikovane predoperativnom analizom AutoCAD. Zubi su rekonstruirani s pomoću K-proširivača #10 i epoksi ljepila. Svaka grupa instrumentirana je jednim od četiriju sustava. Vrijeme inst…

OrthodonticsInstrumentationRoot canalTooth PreparationA diamondDental High-Speed Equipmentlcsh:RK1-715Light sourcemedicine.anatomical_structurelcsh:DentistryStereo microscopemedicineStatistical analysispreparacija korijenskog kanala brzo rotirajuća stomatološka oprema priprema zuba; poprečni presjecicross-sectionsRoot canal anatomyRoot Canal Preparation; Dental High-Speed Equipment; Tooth Preparation; cross-sectionsGeneral DentistryRoot Canal PreparationResearch ArticleMathematicsActa Stomatologica Croatica
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Comparison of Shaping Ability of 10 Rotary and Reciprocating Systems: an In Vitro Study with AutoCAD

2017

Cilj: Usporediti reznu površinu, očuvanje anatomije korijenskog kanala i neinstrumentiranu površinu nakon instrumentacije sustavima F360®, F6SkyTaper®, HyflexEDM®, iRace®, Neoniti®, O.Shape®, P.Next®, Reciproc®, Revo-S® i WaveOneGold® s veličinom instrumenta 25. Materijali i metode: Tristo zubi s jednim ravnim korijenom i okruglim ili eliptičnim presjekom korijenskog kanala podijeljeno je u 10 skupina (1-F360®, 2-F6SkyTaper®, 3-HyflexEDM®, 4-iRace®, 5-Neoniti®, 6-O Shape®, 7-P.Next®, 8-Reciproc®, 9-Revo-S® i 10-WaveOneGold®) i poprečno prerezano na trećine ultrafinim reznim diskovima. Uzorci su fotografirani pod stereomikroskopom i provedena je predinstrumentacijska analiza prije ponovnog s…

OrthodonticsRoot Canal Preparation; Dental HighSpeed EquipmentDental HighSpeed EquipmentRoot canal0206 medical engineering030206 dentistry02 engineering and technology020601 biomedical engineeringlcsh:RK1-715korijenski kanal priprema; brzo rotirajuća stomatološka oprema03 medical and health sciencesReciprocating motion0302 clinical medicinemedicine.anatomical_structurelcsh:DentistryCoronal planeStereo microscopemedicineIn vitro studyStatistical analysisOriginal Scientific PapersRoot canal anatomyGeneral DentistryRoot Canal PreparationMathematicsActa Stomatologica Croatica
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