Search results for "IRRADIATION"

showing 10 items of 1012 documents

Palliative splenic irradiation in primary and post PV/ET myelofibrosis: outcomes and toxicity of three radiation schedules

2009

Splenectomy and splenic irradiation (SI) are the sole treatment modalities to control drug resistant splenomegaly in patients with myelofibrosis (MF). SI has been used in poor surgical candidates but optimal total dose and fractionation are unclear. We retrospectively reviewed 14 MF patients with symptomatic splenomegaly. Patients received a median of 10 fractions in two weeks. Fraction size ranged from 0.2–1.4 Gy, and total dose varied from 2–10.8 Gy per RT course. Overall results indicate that 81.8% of radiation courses achieved a significant spleen reduction. Splenic pain relief and gastrointestinal symptoms reduction were obtained in 94% and 91% of courses, respectively. Severe cytopeni…

medicine.medical_specialtypalliationmedicine.medical_treatmentSplenectomyMyelofibrosisSpleenSubgroup analysisGastroenterologyArticleInternal medicineMedicinemyelofibrosis; splenomegaly; palliation; radiotherapy; low-dose irradiationMyelofibrosisAdverse effectradiotherapylow dose irradiationsplenomegalylcsh:RC633-647.5business.industrylow-dose irradiation.lcsh:Diseases of the blood and blood-forming organsHematologymedicine.diseaseSurgeryRadiation therapymedicine.anatomical_structureTolerabilityToxicitybusinessHematology Reports
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Ex vivoevidence for PGE2and LTB4involvement in cutaneous leishmaniasis: relation with infection status and cytokine production

1996

SUMMARYEx vivoculture of spleen cells from BALB/c mice infected with 2 × 106Leishmania major(L.major) promastigotes were cultured with ConcanavalinA (ConA) or leishmanial antigen (L. Ag) and tested for prostaglandin E2(PGE2) and for leukotriene B4(LTB4), in order to study their involvement in the evolution of cutaneous leishmaniasis and the connexion with lymphokine-mediated responses. The data were compared with those obtained in BALB/c mice protected againstL. majorby sublethal irradiation (550 rad; cured mice). In the unprotected BALB/c mice the levels of PGE2that were responsible for the depression of interferon-γ (IFN-γ) and tumour necrosis factor-α (TNFα) Th1-associated cytokines and …

medicine.medical_treatmentLeishmaniasis CutaneousInflammationLeukotriene B4DinoprostoneInterferon-gammaMiceTh2 CellsImmune systemCutaneous leishmaniasismedicineAnimalsLeishmania majorInterferon gammaCells CulturedLeishmania majorMice Inbred BALB CbiologyTumor Necrosis Factor-alphaTh1 Cellsbiology.organism_classificationmedicine.diseaseInfectious DiseasesCytokineImmunologyFemaleAnimal Science and ZoologyParasitologyTumor necrosis factor alphaInterleukin-4medicine.symptomSpleenWhole-Body IrradiationEx vivomedicine.drugParasitology
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A Dynamic Electrical Scheme for the optimal reconfiguration of PV modules under non-homogeneous solar irradiation

2012

This paper presents a strategy for the maximization of the output power of photovoltaic (PV) systems under non homogeneous solar irradiation by means of automatic reconfiguration of the PV arrays layout. The innovation of the proposed approach is the employment of a simple Dynamic Electrical Scheme (DES), allowing a large number of possible modules interconnection, to be installed between the PV generator and the inverter. The models of the PV generator and of the DES have been realized and simulated with Simulink (Dynamic System Simulation for MATLAB). The attained experimental results appear to be quite interesting in terms of the attainable benefit in power and thus energy terms. The lim…

mismatch for photovoltaic modules optimization reconfigurationEngineeringInterconnectionbusiness.industryPhotovoltaic systemControl reconfigurationPV modules photovoltaic MPPT reconfiguration non-homogeneous solar irradiationGeneral MedicineMaximum power point trackingPower (physics)Settore ING-IND/33 - Sistemi Elettrici Per L'EnergiaSettore ING-IND/31 - ElettrotecnicaControl theoryGrid-connected photovoltaic power systemElectronic engineeringInverterbusinessMATLABcomputercomputer.programming_language
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Application of Molecular Topology for the Prediction of Reaction Yields and Anti-Inflammatory Activity of Heterocyclic Amidine Derivatives

2011

Topological-mathematical models based on multiple linear regression analyses have been built to predict the reaction yields and the anti-inflammatory activity of a set of heterocylic amidine derivatives, synthesized under environmental friendly conditions, using microwave irradiation. Two models with three variables each were selected. The models were validated by cross-validation and randomization tests. The final outcome demonstrates a good agreement between the predicted and experimental results, confirming the robustness of the method. These models also enabled the screening of virtual libraries for new amidine derivatives predicted to show higher values of reaction yields and anti-infl…

multilineal regression analysisQSAR analysisAmidinesAnti-Inflammatory AgentsQuantitative Structure-Activity RelationshipArticleCatalysismolecular topologylcsh:ChemistryInorganic ChemistryAmidineHeterocyclic Compounds 1-Ringchemistry.chemical_compoundComputational chemistryLinear regressionOrganic chemistryPhysical and Theoretical Chemistryyield reactionanti-inflammatory activitylcsh:QH301-705.5Molecular BiologySpectroscopyChemistryOrganic ChemistryGeneral MedicineComputer Science Applicationslcsh:Biology (General)lcsh:QD1-999Microwave irradiationMolecular topologyAlgorithmsamidine derivativesInternational Journal of Molecular Sciences
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Effect of Laser Radiation on Infected Sites for the Immediate Placement of Dental Implants.

2020

Objective: The study aims to evaluate the feasibility of erbium-chromium: yttrium-scandium-gallium-garnet (ErCr:YSGG 2780 nm) laser irradiation on infected and/or inflamed post-extraction sites for...

musculoskeletal diseasesMaleImmediate Dental Implant LoadingBiomedical EngineeringDentistryLasers Solid-StateRadiationlaw.inventionLaser therapylawMedicineHumansSurgical Wound InfectionRadiology Nuclear Medicine and imagingIrradiationTooth Socketbusiness.industryMiddle AgedLaserDisinfectionDebridementBone SubstitutesTooth ExtractionFeasibility StudiesFemalebusinessPhotobiomodulation, photomedicine, and laser surgery
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Understanding generation of multifunctional nanogels in chemical-free e-beam irradation synthesis

2018

Radiation engineered nanogels are the core of very promising theranostic nanodevoces. They can be produced starting from aqueous solutions of chemically inert polymers by pulsed e-beam irradiation.

nanogels e-beam irradiation
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Microwave-assisted synthesis of semiconductor nanoparticles in water/oil microemulsion

2005

Stable CdS and ZnS nanoparticles with exalted luminescence properties have been obtained in water/sodium bis (2-ethylhexyl) sulfosuccinate (AOT)/n-heptane microemulsion using microwave in order to take away selectively water molecules from microemulsion system. The nanoparticles synthesis was performed using a microwave exposure set-up opportunely assembled that allows irradiating the reactor with microwave of 2.45 GHz maintaining constant the temperature. The nanoparticles growth kinetics, as a function of irradiation time, was performed by means of UV-Vis spectroscopy. Information about the structural changes that microemulsion undergoes when irradiated with microwave was obtained by mean…

nanoparticles microwave irradiation microemulsion CdS ZnS.Settore CHIM/02 - Chimica Fisica
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Radioluminescence Response of Ce-, Cu-, and Gd-Doped Silica Glasses for Dosimetry of Pulsed Electron Beams

2021

Radiation-induced emission of doped sol-gel silica glass samples was investigated under a pulsed 20-MeV electron beam. The studied samples were drawn rods doped with cerium, copper, or gadolinium ions, which were connected to multimode pure-silica core fibers to transport the induced luminescence from the irradiation area to a signal readout system. The luminescence pulses in the samples induced by the electron bunches were studied as a function of deposited dose per electron bunch. All the investigated samples were found to have a linear response in terms of luminescence as a function of electron bunch sizes between 10−5 Gy/bunch and 1.5×10−2 Gy/bunch. The presented results show that these…

optical fiberLuminescenceMaterials scienceradiation-induced luminescenceAnalytical chemistryElectronsTP1-118502 engineering and technologyElectronhiukkaskiihdyttimetelektronit01 natural sciencesBiochemistryArticleAnalytical Chemistrylaw.inventionmittauslaitteetlaw0103 physical sciencesDosimetrydosimetritIrradiationElectrical and Electronic EngineeringRadiometryInstrumentation[PHYS]Physics [physics]optiset kuidutdosimetry010308 nuclear & particles physicsChemical technologypulsed electron beamluminesenssiDopingParticle acceleratorRadioluminescenceSilicon Dioxide021001 nanoscience & nanotechnologyelectron acceleratorAtomic and Molecular Physics and Opticspoint dosimeterCondensed Matter::Soft Condensed MattersäteilyfysiikkaCathode rayPhysics::Accelerator Physics0210 nano-technologyLuminescence
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O2-Loading Treatment of Ge-Doped Silica Fibers: A Radiation Hardening Process

2016

International audience; The effects of a high-pressure O2-loading treatment on the radiation response of Ge-doped optical fibers (OFs) were investigated. We found that the incorporation of high concentration of interstitial molecular oxygen remarkably enhances the resistance to ionizing radiation of Ge-doped OFs in the UV-Visible domain and, at the same time, improves the transmission of UV light in the unirradiated OF sample. By comparison with previously reported results, the O2-loading treatment turned out to increase the radiation resistance of Ge-doped OFs more efficiently than F or Ce codoping. The understanding of such amelioration relies in basic radiation-induced mechanisms that we…

optical fiberMaterials scienceAnalytical chemistrychemistry.chemical_elementGermanium02 engineering and technologygermanosilicate01 natural scienceslaw.inventionIonizing radiationOpticslaw0103 physical sciencesIrradiationElectron paramagnetic resonanceRadiation hardeningRadiation resistance[PHYS]Physics [physics]radiation effect010308 nuclear & particles physicsbusiness.industryDopingSettore FIS/01 - Fisica SperimentaleResonance021001 nanoscience & nanotechnologyAtomic and Molecular Physics and Opticschemistry0210 nano-technologybusiness
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Origins of radiation-induced attenuation in pure-silica-core and Ge-doped optical fibers under pulsed x-ray irradiation

2020

We investigated the nature, optical properties, and decay kinetics of point defects causing large transient attenuation increase observed in silica-based optical fibers exposed to short duration and high-dose rate x-ray pulses. The transient radiation-induced attenuation (RIA) spectra of pure-silica-core (PSC), Ge-doped, F-doped, and Ge + F-doped optical fibers (OFs) were acquired after the ionizing pulse in the spectral range of [∼0.8–∼3.2] eV (∼1500–∼380 nm), from a few ms to several minutes after the pulse, at both room temperature (RT) and liquid nitrogen temperature (LNT). Comparing the fiber behavior at both temperatures better highlights the thermally unstable point defects contribut…

optical fiberMaterials scienceOptical fiberAnalytical chemistryGeneral Physics and Astronomy02 engineering and technologymedicine.disease_cause01 natural scienceslaw.inventionx-ray irradiationlaw0103 physical sciencesmedicinepoint defectsRadiation induced absorptionFiberAbsorption (electromagnetic radiation)ComputingMilieux_MISCELLANEOUS010302 applied physics[PHYS]Physics [physics]F dopingAttenuationDopingSettore FIS/01 - Fisica SperimentaleLiquid nitrogen021001 nanoscience & nanotechnologyCrystallographic defectGe doping0210 nano-technologyUltraviolet
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