Search results for "ISOC"
showing 10 items of 301 documents
Effect of sodium dodecyl sulphate and Brij-35 on the analysis of sulphonamides in physiological samples using direct injection and acetonitrile gradi…
2016
Micellar liquid chromatography (MLC) is a reversed-phase (RP) mode, which often does not require gradient elution, since the peaks of mixtures of compounds within a large range of polarities appear more evenly distributed in the chromatograms of isocratic elution, giving rise to a “gradient effect”. However, the use of a gradient of organic solvent may still be convenient to shorten the total analysis time. This work compares the separation of 15 sulphonamides using conventional hydro-organic RPLC and MLC with the surfactants sodium dodecyl sulphate (SDS) and Brij-35, and both isocratic and gradient elution with acetonitrile. The observed behaviour is rationalized attending to the interacti…
Modeling of Retention in Reversed Phase Liquid Chromatography
2015
Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice
2017
Chronic inflammatory skin diseases such as psoriasis have a significant impact on society. Currently, the major topical treatments have many side effects, making their continued use in patients difficult. Microalgae have emerged as a source of bio-active molecules such as glycolipids with potent anti-inflammatory properties. We aimed to investigate the effects of a glycolipid (MGMG-A) and a glycolipid fraction (MGDG) obtained from the microalga Isochrysis galbana on a TPA-induced epidermal hyperplasia murine model. In a first set of experiments, we examined the preventive effects of MGMG-A and MGDG dissolved in acetone on TPA-induced hyperplasia model in mice. In a second step, we performed…
Metodes izstrāde oligonukleotīdu saistības termodinamisku parametru noteikšanai
2020
Maģistra darbā ir oligonukleotīdu dizainēšana, lai varētu detektēt fluorescentus kušanas līknes. Literatūras apskatā aprakstītas metodes, kas pielietotas oligonukleotīdu termodinamisko parametru noteikšanai. Tika izpētīti optimālie parametri fluorescentu kušanas grafiku uzņemšanai. Iegūtie rezultāti paver iespēju jaunai metodei, lai izpētītu termodinamiskos parametrus oligonukleotīdiem.
Personības iezīmju saistība ar vērtējumu par antisociālu uzvedību
2022
Kad runa ir par cilvēku uzvedības un antisociālas uzvedības prognozēšanu, izmantojot personības iezīmes, izrādās, uzdevums ir diezgan sarežģīts. Dažos pētījumos ir atrasti ietekmīgi pierādījumi korelācijai, bet citos tie netiek atrasti. Ikviens var kļūt par antisociālas uzvedības upuri, tā pat kā jebkurš to var veikt. Katrs cilvēks ir indivīds, kura domas, uzskati un vērtības var atšķirties no pārējiem. Tādējādi šīs atšķirības ietekmē arī indivīda skatījumu un toleranci pret antisociālu uzvedību un cilvēkiem, kuri uzvedas antisociāli. Vai pastāv saikne starp indivīda personības iezīmēm un veidu, kā viņi uztver antisociālu uzvedību? Šajā pētījumā mēs meklējam korelācijas starp Lielā piecinie…
Preparation and reactions of palladium(II) complexes with C2-bonded heteroaromatic ligands trans[PdCl(RN)(PPh3)2] (RN = 2-pyridyl, 2-pirazyl, 2-pyrim…
1986
Abstract The complexes trans -[PdCl(R N )(PPh 3 ) 2 ] (I) [R N = 2-pyridyl (2-Py), 2-pyrazyl (2-pyz), 2-pyrimidyl (2-pym) group] have been prepared in high yield by deprotonation with NEt 3 of the corresponding cationic compounds trans [PdCl(R N H) (PPh 3 ) 2 ] + (R N H = N -protonated C 2 -heteroaromatic ligand) in the presence of an excess of PPh 3 . In chlorinated solvents, complexes I undergo a slow reversible dimerization into the binuclear derivatives [PdCl(μ-R N )(PPh 3 )] 2 (II) (μ-R N = C 2 , N 1 -bridging ligand). From the 31 P NMR spectra in 1,2-dichloroethane the following dissociation constants were obtained: 1.9 mol 1 −1 (R N = 2-py), 5.1 × 10 −2 (2-pym), 6.6 × 10 −3 (2-pyz). …
Genetic Influences on Alcohol Use Behaviors Have Diverging Developmental Trajectories: A Prospective Study Among Male and Female Twins
2014
Background Both alcohol-specific genetic factors and genetic factors related to externalizing behavior influence problematic alcohol use. Little is known, however, about the etiologic role of these 2 components of genetic risk on alcohol-related behaviors across development. Prior studies conducted in a male cohort of twins suggest that externalizing genetic factors are important for predicting heavy alcohol use in adolescence, whereas alcohol-specific genetic factors increase in importance during the transition to adulthood. In this report, we studied twin brothers and sisters and brother–sister twin pairs to examine such developmental trajectories and investigate whether sex and cotwin se…
Contribution of Motivational Climates and Social Competence in Physical Education on Overall Physical Activity: A Self-Determination Theory Approach …
2020
Using a cross-sectional study design, we tested a structural equation model of hypothesized relationships among a group of variables: motivational climate in physical education (PE), students&rsquo
Action Representation in Patients with Bilateral Vestibular Impairments
2011
During mental actions subjects feel themselves performing a movement without any corresponding motor output. Although broad information is available regarding the influence of central lesions on action representation, little is known about how peripheral damages affect mental events. In the current study, we investigated whether lack of vestibular information influences action representation. Twelve healthy adults and twelve patients with bilateral vestibular damage actually performed and mentally simulated walking and drawing. The locomotor paths implied one (first walking task) and four (second walking task) changes in the walking direction. In the drawing task, participants drew on a she…
Predictability of oppositional defiant disorder and symptom dimensions in children and adolescents with ADHD combined type.
2010
BackgroundOppositional defiant disorder (ODD) is frequently co-occurring with attention deficit hyperactivity disorder (ADHD) in children and adolescents. Because ODD is a precursor of later conduct disorder (CD) and affective disorders, early diagnostic identification is warranted. Furthermore, the predictability of three recently confirmed ODD dimensions (ODD-irritable, ODD-headstrong and ODD-hurtful) may assist clinical decision making.MethodReceiver-operating characteristic (ROC) analysis was used in order to test the diagnostic accuracy of the Conners' Parent Rating Scale revised (CPRS-R) and the parent version of the Strength and Difficulties Questionnaire (PSDQ) in the prediction of …