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showing 10 items of 3539 documents
Il ricongiungimento dei migranti non comunitari tra sovranità degli stati e tutela dei diritti fondamentali
2007
Carbonyl metallo immuno assay: a new application for Fourier transform infrared spectroscopy
2000
Abstract We describe here the development of a new, non-isotopic immunological assay termed CMIA (carbonyl metallo immunoassay) that uses metal carbonyl complexes as tracers and Fourier transform infrared spectroscopy (FT-IR) as the detection method. This assay is based on the particular spectral features of these complexes, which show very strong absorption bands in the 1800–2200 cm −1 spectral range where proteins and organic molecules do not absorb. In Section 1 , the optimisation of the quantitative detection of these tracers is detailed. In Section 2 , the implementation of mono-CMIA is described, including the CMIA assays of three antiepileptic drugs (carbamazepine, phenobarbital, phe…
Production of specific antibodies and development of a non-isotopic immunoassay for carbamazepine by the carbonyl metallo-immunoassay (CMIA) method.
1995
Abstract As part of our ongoing work to extend the range of applications of the non-isotopic carbonyl metalloimmunoassay (CMIA), previously developed in our laboratory, we describe here the first CMIA study of carbamazepine. The CMIA method uses a metal carbonyl complex as a non-isotopic tracer, and in this case we chose to employ the dicobalt hexacarbonyl moiety (Co2(CO)6) attached to an alkyne. Two organometallic tracers, 3 and 7 , were synthesized, differentiated by the nature and length of the spacer arm of the Co2(CO)6 moiety. Two different coupling methods were subsequently used to synthesize the immunogens 1 and 2, the first one used a carbodiimide, while the second, employed dimethy…
LE IMPRESE SOCIALI Un’analisi degli aspetti di governance e rendicontazione
2012
Negli ultimi anni il numero delle imprese che operano nel terzosettore è aumentato e le attività svolte si sono arricchite di contenuti.Oggi, infatti, le aziende non profit, oltre all’assistenza sociale esanitaria e alla formazione, svolgono attività di tutela dell’ambientee dell’ecosistema, di valorizzazione del patrimonio culturale e del turismosociale, di ricerca ed erogazione di servizi culturali. In questomutato quadro ambientale di riferimento, il legislatore con il D.Lgs155/2006 ha introdotto le imprese sociali, un nuovo strumento giuridicoche permette alle aziende del terzo settore di operare con maggiorefacilità sul mercato. Gli aspetti che caratterizzano queste impresesono due e s…
PREFAZIONE
2009
Selezione e raccolta di saggi di Francesco Luisi in occasione dei suoi sessantacinque anni. Il volume giubilare riunisce gli interventi più originali sulla musica per il teatro del Cinquecento, secondo distinzioni di utenza e genere. L'autore analizza esempi di musica nata per il teatro o per esso adattata, di musica piazzata come intermedio tra gli atti e di musica in forma di canti inseriti nel corso dell'azione con funzione decorativa o drammatica. Si intrattiene altresì sulla qualità degli eventi sonori in relazione ai generi della tragedia, della commedia, della favola pastorale e della sacra rappresentazione. La seconda parte riguarda lo studio delle allegorie musicali e degli aspetti…
Probabilistic inferences from conjoined to iterated conditionals
2017
Abstract There is wide support in logic, philosophy, and psychology for the hypothesis that the probability of the indicative conditional of natural language, P ( if A then B ) , is the conditional probability of B given A, P ( B | A ) . We identify a conditional which is such that P ( if A then B ) = P ( B | A ) with de Finetti's conditional event, B | A . An objection to making this identification in the past was that it appeared unclear how to form compounds and iterations of conditional events. In this paper, we illustrate how to overcome this objection with a probabilistic analysis, based on coherence, of these compounds and iterations. We interpret the compounds and iterations as cond…
Elaboration of ammonia gas sensors based on electrodeposited polypyrrole - cobalt phthalocyanine hybrid films
2013
The electrochemical incorporation of a sulfonated cobalt phthalocyanine (sCoPc) in conducting polypyrrole (PPy) was done, in the presence or absence of LiClO4, in order to use the resulting hybrid material for the sensing of ammonia. After electrochemical deposition, the morphological features and structural properties of polypyrrole/phthalocyanine hybrid films were investigated and compared to those of polypyrrole films. A gas sensor consisting in platinum microelectrodes arrays was fabricated using silicon microtechnologies, and the polypyrrole and polypyrrole/phthalocyanine films were electrochemically deposited on the platinum microelectrodes arrays of this gas sensor. When exposed to a…
Hydantoin-substituted 4,6-dichloroindole-2-carboxylic acids as ligands with high affinity for the glycine binding site of the NMDA receptor.
2002
A novel series of C-3 substituted 4,6-dichloroindole-2-carboxylic acids was synthesized to investigate the influence of different hydrogen-bond donor and acceptor groups at this specific position on the affinity to the glycine site of the NMDA receptor. These novel 3-indolylmethyl derivatives with ring-open (amines, sulfonamides, amides, ureas) and cyclic substituents (imidazolidin-2-ones, (thio)hydantoins) led to the discovery that compounds bearing a hydantoin substituent at the C-3 position of the indole nucleus are the most promising ones. In this series the hydantoins, ureas, and imidazolidin-2-ones were identified as very potent inhibitors of the binding of the glycine site specific l…