Search results for "InVEST"
showing 10 items of 2596 documents
Epistemic and didactic values of the demonstrative process in different cultures: a case study in Geometry with Chinese and Italian students
2011
Histological and immunohistochemical findings in a fatal case of thrombotic thrombocytopenia after ChAdOx1 nCov-19 vaccination
2021
This case report describes a fatal case of a young woman with superior sagittal, transverse and sigmoid sinus thrombosis after administration of the ChAdOx1 nCov-19 vaccination. Eleven days post-vaccination she was found unconscious and transferred to the Emergency Department. Blood parameters showed low platelets, and a CT scan showed an extensive left intracranial hemorrhage and the presence of an occlusive thrombus of the superior sagittal sinus. She under-went a craniectomy, but after the intervention, she remained in a comatose state. After a few days, her clinical conditions worsened, and she died. A complete autopsy was performed which showed a thrombosis of the cerebral venous distr…
A critical evaluation of caplacizumab for the treatment of acquired thrombotic thrombocytopenic purpura
2020
Introduction: Acquired thrombotic thrombocytopenic purpura (aTTP) is a thrombotic microangiopathy caused by inhibitory autoantibodies against ADAMTS13 protein. Until recently, the combination of plasma exchange (PEX) and immunosuppression has been the standard front-line treatment in this disorder. However, aTTP-related mortality, refractoriness, and relapse are still a matter of concern. Areas covered: The better understanding of the pathophysiological mechanisms of aTTP has allowed substantial improvements in the diagnosis and treatment of this disease. Recently, the novel anti-VWF nanobody caplacizumab has been approved for acute episodes of aTTP. Caplacizumab is capable to block the adh…
Origins of the outperformance of venture backed initial public offerings : a French study
2010
In this thesis, we analyze the contractual relationship between private equity investors and entrepreneurs/managers of small and medium sized firms. More specifically, we focus on the real contribution of these financial intermediaries to the Initial Public Offering (IPO) performance of financed firms. While considering venture capitalists’ involvement in the governance of financed firms as the main explaining factor, we use the Corporate Governance theory as the relevant theoretical framework. Thus, we firstly point out the agency theory perspective and secondly the resource and knowledge based view perspective to examine the determinants of venture capitalists’ involvement and the impact …
Early cardiovascular events in women with a history of gestational diabetes mellitus
2016
International audience; Background: The effect of gestational diabetes mellitus (GDM) on cardiovascular diseases (CVD) is not assessed within the first 10 years postpartum, regardless of subsequent diabetes. The aim of this study was to determine the risk of CVD events related to GDM within 7 years of postpartum.Methods: This nationwide population-based study of deliveries in 2007 and 2008 with a follow-up of 7 years was based on data from the French medico-administrative database. Two groups were formed: women with a history of GDM and women without GDM or previous diabetes. CVD included angina pectoris, myocardial infarction, stroke, heart bypass surgery, coronary angioplasty, carotid end…
A central nervous system-focused treatment approach for people with frozen shoulder: protocol for a randomized clinical trial
2019
Background: Frozen shoulder (FS) is a musculoskeletal condition of poorly understood etiology that results in shoulder pain and large mobility deficits. Despite some physical therapy interventions, such as joint mobilization and exercise, having shown therapeutic benefit, a definitive treatment does not currently exist. The aim of this study will be to compare the effectiveness of a central nervous system (CNS)-directed treatment program versus a standard medical and physical therapy care program on outcomes in participants with FS. Methods/design: The study is a two-group, randomized clinical trial with blinding of participants and assessors. Participants will be recruited via referrals fr…
The total social costs of constructing and operating a high-speed rail line using a case study of the Riyadh-Dammam Corridor, Saudi Arabia
2019
Introducing a High-Speed Rail technology between the Saudi Arabian cities starts raising many challenging issues of different nature ranging from technical to operational, which require huge investments in infrastructure, operations and maintenance. Background information about the development of HSR worldwide to date is included. However, the main aim of this paper is to determine a methodology to estimate the full cost of travel and provide insights into the working model developed to include the calculations of the total social costs of building a new HSR line for the Riyadh-Dammam corridor in Saudi Arabia and understand in what circumstances it is a suitable technology to use. The Sprea…
Análisis del comportamiento espacio-temporal intradestino mediante GPS : Una aproximación de los visitantes independientes de crucero en la ciudad de…
2020
El presente trabajo tiene como objetivo profundizar en el análisis de los patrones de comportamiento espacio-temporal de los visitantes en destino, una escala de trabajo insuficientemente desarrollada. La investigación aplica un enfoque multimétodo, que combina el uso de GPS con una encuesta, al conocimiento de los patrones espaciales de los cruceristas que visitan la ciudad de Valencia de manera independiente. Los resultados obtenidos evidencian la polarización de los flujos en el centro histórico de la ciudad, dentro de un patrón mayoritario de único nodo, una dinámica que conviene gestionar adecuadamente para prevenir la congestión y poner en valor otros atractivos urbanos. La redistribu…
The role of ICT, eWOM and guest characteristics in loyalty
2019
Purpose This study aims to examine how technologies contribute to consumer loyalty in the tourist industry. To achieve this objective, information and communication technology (ICT) development and electronic word-of-mouth (eWOM) are analysed to explore their direct and indirect effects on satisfaction and loyalty dimensions. The moderating role of customer characteristics (personal and experience-related variables) is also considered to study the complex relationship between satisfaction and loyalty. Design/methodology/approach A quantitative study based on a questionnaire structured was developed. The survey was conducted with 386 guests from Spanish hotels. SEM methodology is applied to…
Retrospection in interpreting and translation: explaining the process?
2014
Retrospection is one of the few research methods equally suitable for studying the processes involved in both translation and interpreting. At the first workshop on research methods in process-oriented research (Graz 2009), we presented the results of a pilot study of retrospection as a research method, published as Englund Dimitrova & Tiselius (2009). The study involved data from two groups (15 years of professional experience vs. no professional experience), each with 3+3 subjects (interpreter subjects vs. translator subjects, all with Swedish as their L1). The source text was a 10-minute plenary speech in English from the European Parliament, interpreted simultaneously into Swedish. …