Search results for "Induced"
showing 10 items of 1287 documents
Modelling Bacterial Dynamics in Food Products: Role of Environmental Noise and Interspecific Competition
2013
In this paper we review some results obtained within the context of the predictive microbiology, which is a specific field of the population dynamics. In particular we discuss three models, which exploit tools of statistical mechanics, for bacterial dynamics in food of animal origin. In the first model, the random fluctuating behaviour, experimentally measured, of the temperature is considered. In the second model stochastic differential equations are introduced to take into account the influence of physical and chemical variables, such as temperature, pH and activity water, subject to deterministic and random variations. The third model, which is an extended version of the second one, negl…
Noise Induced Phenomena in the Dynamics of Two Competing Species
2015
Noise through its interaction with the nonlinearity of the living systems can give rise to counter-intuitive phenomena. In this paper we shortly review noise induced effects in different ecosystems, in which two populations compete for the same resources. We also present new results on spatial patterns of two populations, while modeling real distributions of anchovies and sardines. The transient dynamics of these ecosystems are analyzed through generalized Lotka-Volterra equations in the presence of multiplicative noise, which models the interaction between the species and the environment. We find noise induced phenomena such as quasi-deterministic oscillations, stochastic resonance, noise …
Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality
2022
[Background and Purpose] Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year.
Study of the role of “gatekeeper” mutations V654A and T670I of c-kit kinase in the interaction with inhibitors by means mixed molecular dynamics/dock…
2011
The over-expression of c-kit proto-oncogene has been reported in hematopoietic cells, small cell lung cancer, and gastrointestinal stromal tumors. The clinical importance of c-kit expression in tumors focused the research towards inhibitors of this tyrosine kinase. Imatinib (Gleevec®) was the first compound used in therapy, but mutations on c-kit led to reduced effectiveness or ineffectiveness of this treatment. Other compounds are likely to be effective against mutants, such as Sunitinib (Sutent®), but the need for new and most effective inhibitors against mutants is still critical. We report mixed Molecular Dynamics/Docking study with the aim to unveil the molecular mechanism involved in …
New perspectives in time-resolved laser-induced electron diffraction
2023
Journal of physics / B 56(5), 054002 (2023). doi:10.1088/1361-6455/acb872
Physically based modeling of rainfall-triggered landslides: a case study in the Luquillo forest, Puerto Rico
2013
This paper presents the development of a rainfall-triggered landslide module within an existing physically based spatially distributed ecohydrologic model. The model, tRIBS-VEGGIE (Triangulated Irregular Networks-based Real-time Integrated Basin Simulator and Vegetation Generator for Interactive Evolution), is capable of a sophisticated description of many hydrological processes; in particular, the soil moisture dynamics are resolved at a temporal and spatial resolution required to examine the triggering mechanisms of rainfall-induced landslides. The validity of the tRIBS-VEGGIE model to a tropical environment is shown with an evaluation of its performance against direct observations made w…
New design and simulation of the ion guide for neutron-induced fission products at the IGISOL facility
2023
Measurements of independent fission yield distributions in neutron-induced fission at high neutron energies are important for our fundamental understanding of the fission process, and are also relevant for reactor physics applications. So far, measurements of independent fission yields in proton-induced fission have been performed at the IGISOL facility at the University of Jyväskylä, using the Penning trap as a high resolving-power mass-filter. In order to also facilitate measurements of neutron-induced fission, a dedicated ion guide and a proton-to-neutron converter was developed. However, the first measurement indicates that fewer fission products than expected reach the Penning trap. To…
Light-induced superconductivity
2016
Intense light pulses irradiating a sample of K3C60 result in dramatic changes of its high-frequency (terahertz) conductivity. Could these be signatures of fleeting superconductivity at 100 K and beyond?
Cerebral expression of neuroglobin and cytoglobin after deep hypothermic circulatory arrest in neonatal piglets
2010
Deep hypothermic circulatory arrest (DHCA) is used in corrective cardiac surgery for complex congenital heart disease. Endogenous protective mechanisms may be responsible for the prevention of brain damage after hypothermic ischemia. Neuroglobin and cytoglobin are expressed in brain cells and appear to modulate hypoxic-ischemic brain injury. However, their neuroprotective potency is still not understood. Thus the aim of this study was to detect the influence exerted by DHCA on their expression.The effects of DHCA were analyzed in a neonatal piglet model with cardiopulmonary bypass, DHCA of 60 and 120 min and subsequent reperfusion of 6h. Complete histological analysis and changes in the mRN…
Cutting Edge: A Key Pathogenic Role of IL-27 in T Cell- Mediated Hepatitis
2007
Abstract The signals driving T cell activation in T cell-mediated fulminant hepatitis are not fully understood. In this study, we identify the cytokine IL-27p28/EBI3 as a major pathogenic factor in the ConA model of T cell-mediated hepatitis. We found an up-regulation of hepatic EBI3 and p28 expression and augmented levels of IL-27 in wild-type mice after ConA administration, suggesting a potential pathogenic role of this cytokine in ConA hepatitis. Consistently, IL-27 EBI3-deficient mice were almost completely protected from ConA-induced liver damage. Such protection was associated with reduced levels of IFN-γ and its signaling proteins pSTAT-1 and T-bet. Finally, in vivo blockade of IL-27…