Search results for "Injury"

Lesión medular y ejercicio físico: revisión desde una perspectiva deportiva

2016

Una de cada 2000 personas en Europa tiene lesión medular (LM), es normalmente más sedentaria que el resto de la población y encuentra diferentes problemas para practicar ejercicio físico (EF), destacando la escasa formación específica de los profesionales del deporte. Con el objetivo de aportar información sobre la LM y su interacción con la práctica deportiva, se realizó una revisión de literatura científica que analiza sus alteraciones músculoesqueléticas, cardiovasculares, respiratorias, de termorregulación, genitourinarias e intestinales, las úlceras por presión, la disreflexia autonómica y los aspectos nutricionales, generando recomendaciones prácticas. Como conclusión, la práctica hab…

IPSIM-Cirsium, a Qualitative Expert-Based Model to Predict Infestations of Cirsium arvense

2021

Throughout Europe, Cirsium arvense is the most problematic perennial weed in arable crops, whether managed under organic or conventional agriculture. Non-chemical control methods are limited with partial efficacy. Knowledge is missing on their effect across a wide gradient of cropping systems and pedoclimates. To achieve effective Cirsium arvense management ensuring crop productivity while limiting the reliance of cropping systems on herbicide, expert-based models are needed to gather knowledge on the effect of individual levers and their interactions in order to (i) design and assess finely tuned combinations of farming practices in different pedoclimates and (ii) support decisions for Cir…

Challenges influencing the safety of migrant workers in the construction industry: A qualitative study in Italy, Spain, and the UK

2021

Abstract The construction industry is notoriously high risk for accidents, injuries, and deaths, particularly for non-national or migrant workers, who comprise a significant proportion of the workforce. This paper presents an international, qualitative study focused on exploring the challenges which influence the safety of migrant construction workers in Italy, Spain, and the UK. Based on a comprehensive review of the literature, we formulated two research questions about the challenges relating to safety that migrant workers face and the challenges to safety training effectively improving migrant workers’ safety behaviours. We present our template analysis of semi-structured interviews and…

A systematic review of human behaviour in and around floodwater

2020

Abstract Flooding can have a major impact on people's safety and livelihood. Understanding people's flood-related behaviours may assist in the development of more effective strategies aimed at lessening the impact of floods including mortality and morbidity. This systematic review examined peer-reviewed literature published from January-1989 to April-2019 on human behaviour in and around floodwater to identify behaviour patterns as well as protective and risk factors. We extracted three main themes from a thematic analysis of included studies (N = 54): activities and risk-taking behaviours (n = 24); loss reduction, knowledge, and warnings (n = 37); and diet and hygiene (n = 4). This review …

La rétropulsion du sujet âgé: mise au point sur un symptôme grave et proposition d'une échelle pour une évaluation quantifiée

2007

Resume Propos Bien qu'il n'existe a l'heure actuelle aucune donnee epidemiologique sur la retropulsion, ce trouble postural semble relativement frequent chez le sujet âge fragile. Actualites et points forts La retropulsion se caracterise par un dejettement posterieur du tronc en position assise, une insuffisance d'avancee du tronc dont la projection du tronc au sol est situee en arriere de la base de sustentation lors du passage assis–debout et une tendance a la chute en arriere en position debout. Plusieurs situations pathologiques aussi bien somatiques (lesions cerebrales degeneratives, ischemiques, traumatiques), que psychosomatiques (syndrome de desadaptation psychomotrice, alitement pr…

Cardiac troponin elevation in patients with influenza virus infections

2021

The association between acute infections and cardiac injury, including myocarditis and acute myocardial infarction, is now well established. We have performed a systematic literature review for analyzing the results of epidemiological studies that measured cardiac troponins (cTn) in patients with Influenza virus infections. Overall, 14 articles were finally identified and analyzed. Taken together, the results of the scientific literature suggest that cTn elevation is a relatively rare phenomenon in patients with Influenza virus infection, with frequency generally comprised between 0 and 33%, more likely in elderly patients with significant comorbidities. In patients with modest cTn elevatio…

Adult rat myelin enhances axonal outgrowth from neural stem cells.

2018

Axon regeneration after spinal cord injury (SCI) is attenuated by growth inhibitory molecules associated with myelin. We report that rat myelin stimulated the growth of axons emerging from rat neural progenitor cells (NPCs) transplanted into sites of SCI in adult rat recipients. When plated on a myelin substrate, neurite outgrowth from rat NPCs and from human induced pluripotent stem cell (iPSC)-derived neural stem cells (NSCs) was enhanced threefold. In vivo, rat NPCs and human iPSC-derived NSCs extended greater numbers of axons through adult central nervous system white matter than through gray matter and preferentially associated with rat host myelin. Mechanistic investigations excluded …

2019

Traumatic brain injury (TBI) is a frequent pathology and associated with poor outcome in the aged population. We recently observed accelerated cerebral inflammation in aged mice in response to TBI. Candesartan is a potent specific inhibitor of angiotensin II receptor type 1 (AT1) which limits cerebral inflammation and brain damage in juvenile animals after experimental TBI. In the present study, we show significantly lower posttraumatic AT1 mRNA levels in aged (21 months) compared to young (2 months) mice. Despite low cerebral At1 expression, pharmacologic blockade by treatment with candesartan (daily, beginning 30 minutes after experimental TBI by controlled cortical impact [CCI]) was high…

Role of Regular Physical Activity in Neuroprotection against Acute Ischemia

2020

One of the major obstacles that prevents an effective therapeutic intervention against ischemic stroke is the lack of neuroprotective agents able to reduce neuronal damage; this results in frequent evolution towards a long-term disability with limited alternatives available to aid in recovery. Nevertheless, various treatment options have shown clinical efficacy. Neurotrophins such as brain-derived neurotrophic factor (BDNF), widely produced throughout the brain, but also in distant tissues such as the muscle, have demonstrated regenerative properties with the potential to restore damaged neural tissue. Neurotrophins play a significant role in both protection and recovery of function followi…

Hepatoprotective effects of extracts, fractions and compounds from the stem bark of Pentaclethra macrophylla Benth: Evidence from in vitro and in viv…

2021

Abstract Aim To identify the bioactive hepatoprotective components of the ethanol extract of Pentaclethra macrophylla stem bark using in vitro and in vivo approaches. Methods The bioguided-fractionation of the ethanol extract was based on the substances’ capacity to prevent in vitro, the lipid peroxidation of hepatocytes’ membranes induced by hydrogen peroxide. For the in vivo hepatoprotective test, mice were treated orally with the ethyl acetate (EtOAc) fraction of the ethanol extract at doses of 50 and 75 mg/kg/day for one week and subjected to d -galactosamine/lipopolysaccharide (GaIN/LPS)-induced hepatotoxicity. Blood samples were collected for alanine aminotransferase (ALAT), aspartate…