Search results for "Ink"

showing 10 items of 4279 documents

Synchronizing the release rates of salicylate and indomethacin from degradable chitosan hydrogel and its optimization by definitive screening design.

2018

Abstract Three types of ionically crosslinked (with citric acid) chitosan discs were loaded with the highly water- soluble drug, sodium salicylate (SS) and the poorly water-soluble drug, indomethacin (Ind). In separate experiments the hydrated discs were immersed in a de-crosslinking solution comprising of different concentrations of calcium chloride, which induced a controlled erosion of the discs, a process which was optimized to synchronize the release rates of the two drugs over a predetermined period of time. The optimization was accomplished by manipulating six factors: chitosan MW, its amount in the formulation, the concentration of the crosslinker agent, the concentration of the de-…

3003DrugSynchronized release ratemedia_common.quotation_subjectIndomethacinPharmaceutical Sciencechemistry.chemical_elementmacromolecular substances02 engineering and technologyCalciumTriggered erosionCitric AcidChitosan03 medical and health scienceschemistry.chemical_compoundCrosslinked chitosan0302 clinical medicineDrug Delivery SystemsScreening designMultifactorial definitive screening designDissolutionSodium salicylatemedia_commonChitosanChromatographytechnology industry and agricultureHydrogelsCrosslinked chitosanDual drug platform021001 nanoscience & nanotechnologyDrug LiberationCross-Linking Reagentschemistry030220 oncology & carcinogenesisDrug Design0210 nano-technologyCitric acidSalicylic AcidEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
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Alkoholinkäytön aiheuttama liikennekuoleman riski Suomessa

2023

Tässä tutkimuksessa analysoidaan juopumuksen asteen vaikutusta kuolemaan johtavan liikenneonnettomuuden riskiin moderneilla tilastollisilla menetelmillä. Tutkimuksen pääaineistona ovat vuosina 2005–2014 Suomessa tapahtuneet kuolemaan johtaneet moottoriajoneuvo-onnettomuudet, joissa oli mukana henkilöauto aiheuttajana tai muuna osallisena. Pääaineistoa täydennetään ratsiatutkimuksista julkaistuilla tilastoilla. Keskeisiä käytettyjä mittareita ovat riskisuhde sekä vakioitu riskisuhde, josta on poistettu sekoittavien muuttujien vaikutusta. Tutkimuksen ensimmäisenä tavoitteena on selvittää, miten pieni veren alkoholipitoisuus alkaa lisätä liikenneonnettomuuden riskiä, ja toisena tavoitteena on …

3142 Kansanterveystiede ympäristö ja työterveys112 Tilastotiedeliikennejuopumusliikenneturvallisuusliikenneonnettomuudetalkoholinkäyttöalkoholi (päihteet)riskitliikennekuolemat
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3D numerical modeling of an anthropogenic sinkhole in the Marsala area of western Sicily

2013

3D modeling Sinkhole MarsalaSettore GEO/04 - Geografia Fisica E GeomorfologiaSettore GEO/05 - Geologia Applicata
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The emerging role of 3D printing in the fabrication of detection systems

2021

Abstract 3D printing is fast evolving as an additive manufacturing technique that has been adopted in (bio)analytical science because of the ample variety of materials and technologies currently available for highly affordable prototyping. This review focuses on the unique characteristics of 3D printing for manufacturing of optical and electrochemical detection systems, and sampling interfaces for analytical purposes using fused deposition modelling, vat polymerization (stereolithography and digital light processing) and photopolymer inkjet printing. The majority of works surveyed within the time span of mid-2018 to mid-2020 encompassed the fabrication of several components of the detection…

3d printedFabricationEmerging technologiesComputer sciencebusiness.industry010401 analytical chemistry3D printingElectrochemical detection01 natural sciences0104 chemical sciencesAnalytical Chemistrylaw.inventionlawSystems engineeringDigital Light ProcessingbusinessSpectroscopyStereolithographyInkjet printingTrAC Trends in Analytical Chemistry
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Existence de points fixes enlacés à une orbite périodique d'un homéomorphisme du plan

1992

Let f be an orientation-preserving homeomorphism of the plane such that f-Id is contracting. Under these hypotheses, we establish the existence, for every periodic orbit, of a fixed point which has nonzero linking number with this periodic orbit.

55M20 54H20Surfaces homeomorphismsPlane (geometry)Applied MathematicsGeneral Mathematics010102 general mathematics[ MATH.MATH-DS ] Mathematics [math]/Dynamical Systems [math.DS][MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS]Linking numberFixed pointLinking numbers01 natural sciencesHomeomorphism010101 applied mathematicsCombinatoricssymbols.namesakesymbolsPeriodic orbitsPeriodic orbitsAstrophysics::Earth and Planetary AstrophysicsMathematics - Dynamical Systems0101 mathematicsMSC : 55M20 54H20Mathematics
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Kaltoinkohtelun muistot lapsuudesta : muistitietotutkimus vaikuttamassa yhteiskuntaan

2022

publishedVersion Peer reviewed

615 Historia ja arkeologiamuistotlastensuojelumenneisyyskokemuskerrontahistoriapolitiikkahyvityskokemuksetmuistitietosijoitetut lapsetvoimaantuminenkaltoinkohtelutraumat
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PINK1: a critical protein kinase in the molecular mechanisms involved in Cancer and Parkinson's disease

2012

El cáncer y la enfermedad de Parkinson (PD) son dos enfermedades en las que el mecanismo pato- fisiológico final no está completamente definido. Datos epidemiológicos indican que los pacientes con PD poseen bajo riesgo de cáncer, con la excepción de melanoma maligno y cánceres de piel, tiroides y mama, lo que sugiere una conexión funcional entre PD y cáncer. Apoyando esta conexión, la desregulación de la homeostasis mitocondrial es una característica importante en la patogénesis de ambas enfermedades. Recientemente, varios genes asociados a PD, tales como Parkin, LRRK2, DJ-1, y PINK1, han sido propuestos como moduladores de procesos cancerígenos. Mutaciones en el gen de PINK1 están asociada…

:CIENCIAS DE LA VIDA::Bioquímica [UNESCO]UNESCO::CIENCIAS DE LA VIDA::Biología molecularPINK1proliferationUNESCO::CIENCIAS DE LA VIDA::Bioquímicainvasion:CIENCIAS DE LA VIDA::Biología molecular [UNESCO]mitochondriacell deathmitophagySer/Thr kinaseparkinson's diseaseoxidative stresscancercell cyclemitochondrial homeostasis
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De la prohibición del terrorismo on-line : una reflexión constitucional

2021

The paper thinks out loud on the banning of the terrorist´s contents on the Internet, specifically within the international and national legal framework, with the interpretation given by the European Court´s of Human Right case-law and our Constitutional Court´s case-law.

:CIENCIAS JURÍDICAS [UNESCO]2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055236 De la prohibición del terrorismo on-line una reflexión constitucional Álvarez Rodríguezspecifically within the international and national legal frameworkInternetConstitutionUNESCO::CIENCIAS JURÍDICASwith the interpretation given by the European Court´s of Human Right case-law and our Constitutional Court´s case-law. ConstituciónterrorismoterrorismIgnacio The paper thinks out loud on the banning of the terrorist´s contents on the InternetInternet 732 757
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Reflections about the authentic document in "post mortem" fecundation

2018

[EN] The legislation on assisted reproduction contemplates the ¿post mortem¿ fecundation. Nevertheless, the document for the presentation of the assent raises some doubts in relation with the principle of party autonomy and the new technologies of the information and communication (ICTs). In the present work one thinks about these questions and one tries to contribute some solution of application in the Spanish legal system.

:CIENCIAS JURÍDICAS [UNESCO]Documento indubitadoFecundación post mortemfecundación ?post mortem?Authentic documentthe document for the presentation of the assent raises some doubts in relation with the principle of party autonomy and the new technologies of the information and communication (ICTs). In the present work one thinks about these questions and one tries to contribute some solution of application in the Spanish legal system. Documento indubitadoDERECHO CIVILLegislaciónUNESCO::CIENCIAS JURÍDICAS2386-4567 22661 Actualidad jurídica iberoamericana 502169 2018 9 6653336 Reflexiones acerca del documento indubitado en la fecundación ?post mortem? Ramón Fernándezlegislación.post mortem fecundationFrancisca The legislation on assisted reproduction contemplates the ?post mortem? fecundation. Nevertheless
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La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apo…

2021

It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this project, the extended parental authority and the rehabilitated parental authority are eliminated from the scope of disability, following a criterion that demands the treatment of people with disabilities with the attention that their specific situation requires, eliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabiliti…

:CIENCIAS JURÍDICAS [UNESCO]parental authorityrehabilitacióneliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabilities. This study is linked and addressedas they will be affected by the reform and by the effect of the structural deficiencies suffered by the Justice system of our country. the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Bill of Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of its legal capacity. In this projectelimination 236 251eliminaciónrehabilitationPablo It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this projectprojectproyectoUNESCO::CIENCIAS JURÍDICASthe extended parental authority and the rehabilitated parental authority are eliminated from the scope of disabilitypatria potestadExtensionwith the characteristics and needs of people with a severe intellectual disabilityas they will be affected by the reform and by the effect of the structural insufficiencies suffered by the Justice system of our country. Prórroga2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055222 La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apoyo a las personas con discapacidad (actual ley 8/2021) Tortajada Chardífollowing a criterion that demands the treatment of people with disabilities with the attention that their specific situation requireshealth care economics and organizations
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