Search results for "Insula"

showing 10 items of 735 documents

Localization of emotional and volitional facial paresis.

1992

Emotional facial paresis is characterized by impaired activation of face muscles with emotion but normal voluntary activation. We report seven patients with this sign. Their lesions involved the frontal lobe white matter, the striatocapsular territory, the anterolateral thalamus and insula, the posterior thalamus and operculum, and the mesial temporal lobe and insula each in one patient, and the posterior thalamus in two patients. Volitional facial paresis affects facial movements with voluntary effort, sparing activation on emotion. We report four such patients, with lesions involving the motor cortex in one and the pyramidal tract in the cerebral hemisphere in three.

AdultMaleVolitionEmotionsFacial ParalysisTemporal lobemedicineHumansOperculum (brain)ParesisAgedPyramidal tractsBrainAnatomyMiddle AgedMagnetic Resonance ImagingFacial musclesmedicine.anatomical_structurenervous systemFrontal lobeCerebral hemisphereFemaleNeurology (clinical)medicine.symptomPsychologyInsulaNeurology
researchProduct

Evidence for modulation of opioidergic activity in central vestibular processing: A [(18)F] diprenorphine PET study.

2009

Animal and functional imaging studies had identified cortical structures such as the parieto‐insular vestibular cortex, the retro‐insular cortex, or the anterior cingulate cortex belonging to a vestibular cortical network. Basic animal studies revealed that endorphins might be important transmitters involved in cerebral vestibular processing. The aim of the present study was therefore to analyse whether the opioid system is involved in vestibular neurotransmission of humans or not. Changes in opioid receptor availability during caloric air stimulation of the right ear were studied with [(18)F] Fluoroethyl‐diprenorphine ([(18)F]FEDPN) PET scans in 10 right‐handed healthy volunteers and compa…

AdultMalemedicine.drug_classDiprenorphineBlood PressureInsular cortexDizzinessSynaptic TransmissionOpioid receptorCortex (anatomy)Physical Stimulationmedicineotorhinolaryngologic diseasesHumansRadiology Nuclear Medicine and imagingAnterior cingulate cortexResearch ArticlesVestibular systemOpioidergicRadiological and Ultrasound TechnologyBrainVestibular cortexmedicine.anatomical_structureNeurologyPositron-Emission TomographyReceptors OpioidVertigoNeurology (clinical)sense organsVestibule LabyrinthAnatomyPsychologyDiprenorphineNeurosciencemedicine.drugHuman brain mapping
researchProduct

Auditory temporal processing deficits in patients with insular stroke

2006

OBJECTIVE: To assess central auditory function in a series of patients with stroke of the insula and adjacent areas. METHODS: The authors recruited eight patients with stroke affecting the insula and adjacent areas and eight neurologically normal controls (matched to the patients for age, sex, handedness, and hearing thresholds). The lesion spared the adjacent auditory areas in three patients and included other auditory structures in five cases. The authors conducted pure-tone audiometry and tympanometry and a central auditory test battery, which included the dichotic digits, and three temporal tests, the duration pattern, frequency pattern, and gaps in noise tests. They collected informati…

AdultMalemedicine.medical_specialtyAuditory areaAudiologyLesionAudiometrymedicineHumansNeuropsychological assessmentHearing DisordersStrokeAgedCerebral CortexSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicamedicine.diagnostic_testDichotic listeningMiddle AgedTympanometrymedicine.diseaseSurgeryStrokeAdult Aged Audiometry Cerebral Cortex/pathology* Female Hearing Disorders/diagnosis Hearing Disorders/etiology Humans Male Middle Aged Stroke/complications Stroke/diagnosisFemaleNeurology (clinical)medicine.symptomAudiometryPsychologyInsulaNeurology
researchProduct

Obesity status and obesity-associated gut dysbiosis effects on hypothalamic structural covariance

2021

[Background]: Functional connectivity alterations in the lateral and medial hypothalamic networks have been associated with the development and maintenance of obesity, but the possible impact on the structural properties of these networks remains largely unexplored. Also, obesity-related gut dysbiosis may delineate specific hypothalamic alterations within obese conditions. We aim to assess the effects of obesity, and obesity and gut-dysbiosis on the structural covariance differences in hypothalamic networks, executive functioning, and depressive symptoms.

AdultMalemedicine.medical_specialtyDisbiosisEndocrinology Diabetes and MetabolismHypothalamusMedicine (miscellaneous)StriatumIntestines -- MicrobiologyArticleBody Mass IndexGlàndules endocrinesInternal medicineNeural PathwaysmedicineHumansObesityEndocrine glandsNutrition and DieteticsHipotàlembusiness.industryFunctional connectivityMiddle Agedmedicine.diseaseObesityIntestins -- MicrobiologiaCross-Sectional StudiesEndocrinologyHypothalamusStructural covarianceObesitatDysbiosisFemaleGut dysbiosisbusinessInsulaHypothalamic DiseasesExecutive dysfunction
researchProduct

Preserved visual-vestibular interaction in patients with bilateral vestibular failure

2004

Background: During caloric vestibular stimulation, subjects showed bilateral activation of the vestibular cortex in the posterior insula and retroinsular region as well as concurrent deactivation of visual cortex areas bilaterally. This finding was the basis for the concept of a reciprocal inhibitory interaction between the vestibular and the visual systems. Objective: To analyze the modulations of this activation and deactivation pattern in patients with loss of vestibular input, that is, in patients with bilateral vestibular failure (BVF). Methods: Modulations of regional cerebral blood flow (rCBF) in PET were measured in nine patients with BVF and compared with those in healthy volunteer…

AdultMalemedicine.medical_specialtyFeedback PsychologicalModels NeurologicalAudiologyStatistical parametric mappingNystagmus PathologicTemporal lobeParietal LobeCaloric Testsotorhinolaryngologic diseasesmedicineHumansAgedVisual CortexVestibular systemReflex AbnormalParietal lobeReflex Vestibulo-OcularMiddle AgedVestibular cortexTemporal LobeVisual cortexmedicine.anatomical_structureVestibular DiseasesCerebrovascular CirculationPositron-Emission TomographySubtraction TechniqueVestibular nystagmusFemaleVestibule Labyrinthsense organsNeurology (clinical)PsychologyInsula
researchProduct

Differential effects on the laser evoked potential of selectively attending to pain localisation versus pain unpleasantness

2004

Abstract Objective : To determine the effects on the laser evoked potential (LEP) of selectively attending to affective (unpleasantness) versus sensory-discriminative (localisation) components of pain. Methods : LEPs, elicited by painful CO 2 laser stimulation of two areas of the right forearm, were recorded from 62 electrodes in 21 healthy volunteers, during three tasks that were matched for generalised attention: Localisation (report stimulus location), Unpleasantness (report stimulus unpleasantness), Control (report pain detection). LEP components are named by polarity, latency, and electrode. Results : N300-T7 peak amplitude was significantly greater during Localisation than Unpleasantn…

AdultMalemedicine.medical_specialtyLaser-Evoked PotentialsPainAudiologyStimulus (physiology)Somatosensory systemEvoked Potentials SomatosensoryPhysiology (medical)Reaction TimeNoxious stimulusmedicineHumansAttentionEvoked potentialPain MeasurementAnalysis of VarianceSecondary somatosensory cortexLasersSensory SystemsNeurologySomatosensory evoked potentialFemaleNeurology (clinical)PsychologyInsulaNeuroscienceClinical Neurophysiology
researchProduct

Neural correlates of disturbed perception of verticality.

2012

Objective: Perception of verticality can be perturbed after cortical stroke. However, a relationship between lesion location and pathologic perception of verticality is still a matter of debate since previous studies revealed contradictory results. Thus, the aim of the current study was to test whether specific cortical lesions were associated with tilts of subjective visual vertical (SVV) and to determine the critical brain areas that cause such tilts in the case of a lesion. Methods: SVV was systematically studied in 54 patients (22 patients with left-sided and 32 patients with right-sided lesions) with acute unilateral strokes, analyzed by modern voxel-wise lesion-behavior mapping techni…

AdultMalemedicine.medical_specialtygenetic structuresInferior frontal gyrusAudiologyInsular cortexLateralization of brain functionLesionPerceptual DisordersSuperior temporal gyrusMedicineHumansAgedVestibular systemAged 80 and overNeural correlates of consciousnessBrain Mappingbusiness.industryBrainFascicleMiddle AgedStrokeSpace PerceptionFemaleNeurology (clinical)medicine.symptombusinessNeurology
researchProduct

Fixation suppression of optokinetic nystagmus modulates cortical visual-vestibular interaction.

2005

Water activation positron emission tomography and statistical group analysis were used to evaluate differences in activation-deactivation patterns during small-field visual motion stimulation, eliciting rightward optokinetic nystagmus and its fixation suppression in 12 healthy volunteers. Bilateral patterns of activation in the visual cortex, including the motion-sensitive area MT/V5, and deactivations in an assembly of vestibular areas (posterior insula, thalamus, anterior cingulate gyrus) during optokinetic nystagmus was markedly diminished or totally absent during its fixation suppression. This finding agrees with the concept of a reciprocal inhibitory interaction between the visual-opto…

AdultMalemedicine.medical_specialtygenetic structuresThalamusSensory systemStimulationFixation OcularAudiologymedicineHumansNystagmus OptokineticAgedVisual CortexVestibular systemBrain MappingGeneral NeuroscienceOptokinetic reflexReflex Vestibulo-OcularMiddle Agedeye diseasesVisual cortexmedicine.anatomical_structureCerebrovascular CirculationPositron-Emission TomographyFixation (visual)Visual PerceptionPsychologyNeuroscienceInsulaPhotic StimulationNeuroreport
researchProduct

New Neandertal remains from Cova Negra (Valencia, Spain).

2005

New Neandertal fossils from the Mousterian site of Cova Negra in the Valencia region of Spain are described, and a comprehensive study of the entire human fossil sample is provided. The new specimens significantly augment the sample of human remains from this site and make Cova Negra one of the richest human paleontological sites on the Iberian Peninsula. The new specimens include cranial and postcranial elements from immature individuals and provide an opportunity to study the ontogenetic appearance of adult Neandertal characteristics in this Pleistocene population. Children younger than 10 years of age constitute four of the seven minimum number of individuals in the sample, and this rela…

AdultNeanderthalPleistoceneMinimum number of individualsAdolescentPopulationPostcraniaContext (language use)Bone and BonesAnthropology PhysicalPaleontologyPeninsulabiology.animalAnimalsHumansFemureducationChildEcology Evolution Behavior and Systematicseducation.field_of_studygeography.geographical_feature_categorybiologyFossilsSkullMousterianHominidaeArchaeologyRadiusGeographySpainAnthropologyChild PreschoolToothJournal of human evolution
researchProduct

Performance Analysis of Innovative Vacuum Insulation Panel

2013

Thermal insulation has become one of the central themes in energy behavior improvement. The use of insulating materials, from the thermal and hydrothermal aspect, allows the reduction of the heat transfer in each of the technical elements increasing their thermal inertia. Even if the research has led to the use of innovative materials with high values of thermal insulation, one of the main problems, which is difficult to resolve, is the thickness of the building envelope to reach levels of transmittance that can allow considerable savings of energy and CO2 emissions. With this objective the VIP (Vacuum Insulation Panel) technology in building applications is an innovative solution to obtain…

Advanced Materials Building Technologies Insulating Performance Retrofit Thermal ConductivitySettore ICAR/10 - Architettura Tecnica
researchProduct