Search results for "Intention"

showing 10 items of 453 documents

Double-blind, randomized, placebo-controlled trial of allergen-specific immunotherapy with the major allergen Alt a1

2019

Background: There have been few studies conducted on the efficacy and safety of specific immunotherapy with allergen extracts of fungi compared with other allergen extracts, and there are no data on the major allergen Alt a 1 of the fungus Alternaria alternata. Objectives: We sought to evaluate the efficacy and safety of subcutaneous immunotherapy with 2 different doses of Alt a 1 in patients with rhinoconjunctivitis caused by sensitization to A alternata. Method: We performed a multicenter, randomized, double-blind, placebo-controlled trial with Alt a 1 administered subcutaneously in patients with allergic rhinoconjunctivitis with or without controlled asthma aged 12 to 65 years. Three gro…

AdultMalesafetyAllergymedicine.medical_specialtyAllergen immunotherapyAl·lèrgiaAdolescentImmunologyefficacyPlacebo-controlled studyPlacebomedicine.disease_causeFungal ProteinsYoung AdultAllergenDouble-Blind Methodchildrensubcutaneous immunotherapyInternal medicinemedicineadultsImmunology and AllergyHumansmolecular immunotherapyAdverse effectChildAgedConjunctivitis AllergicAllergen immunotherapyIntention-to-treat analysisbusiness.industryrhinoconjunctivitisclinical trialAllergensImmunoglobulin EMiddle Agedmedicine.diseaseAsthmaClinical trialfungal allergyDesensitization ImmunologicImmunoglobulin GAlt a 1Femalebusinesspurified allergen
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The mediating role of constructs representing reasoned-action and automatic processes on the past behavior-future behavior relationship.

2020

Abstract Objective Past behavior has been consistently shown to predict and explain future behavior. It has been proposed that past behavior effects reflect both reasoned action and automatic processes. The current study sought to explore the mediation of past behavior-future behavior relationship via constructs reflecting these processes across three populations and behaviors: binge drinking in university students, flossing in adults, and parental sun safety behavior of children 2 – 5 years of age. Furthermore, this study used a measure of past behavior that combined long-term, recent, and routine patterns of behavioral engagement. Method A prospective design with two waves of data collect…

AdultMediation (statistics)Health (social science)media_common.quotation_subjectHealth BehaviorAutomaticityBinge drinkingIntentionStructural equation modelingDevelopmental psychology03 medical and health sciencesHabits0302 clinical medicineHistory and Philosophy of ScienceSocial cognitionHumans030212 general & internal medicineProspective StudiesChildmedia_commonData collection030503 health policy & servicesAction (philosophy)AttitudeHabit0305 other medical sciencePsychologySocial sciencemedicine (1982)
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Efficacy of short-term psychodynamic psychotherapy (STPP) with depressed breast cancer patients: results of a randomized controlled multicenter trial.

2014

BACKGROUND There is a lack of trials of psychodynamic treatments of depression in breast cancer patients. The purpose of this trial was to determine the efficacy of short-term psychodynamic psychotherapy (STPP) in non-metastatic breast cancer patients diagnosed with depression, one of the most frequent mental comorbidities of breast cancer. PATIENTS AND METHODS In a multicenter prospective trial, 157 breast cancer patients with comorbid depression were randomized to either individual STPP (intervention group, N=78) or 'treatment as usual' (control group, TAU, N=79). As our primary outcome measure, we hypothesized a higher rate of remission defined as no diagnosis of depression (Structured C…

Adultmedicine.medical_specialtyAdolescentBreast NeoplasmsHospital Anxiety and Depression ScaleYoung AdultBreast cancerQuality of lifeInternal medicineMulticenter trialmedicineHumansProspective StudiesPsychiatryDepression (differential diagnoses)AgedPsychodynamic psychotherapyIntention-to-treat analysisbusiness.industryDepressionHematologyMiddle Agedmedicine.diseaseComorbidityTreatment OutcomeOncologyQuality of LifeFemalebusinessPsychotherapy PsychodynamicAnnals of oncology : official journal of the European Society for Medical Oncology
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Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovaria…

2013

Summary Background In the Gynecologic Cancer Intergroup International Collaboration on Ovarian Neoplasms 7 (ICON7) trial, bevacizumab improved progression-free survival in patients with ovarian cancer when used in combination with first-line chemotherapy and as a single-drug continuation treatment for 18 cycles. In a preliminary analysis of a high-risk subset of patients, there was also an improvement in overall survival. This study aims to describe the health-related quality-of-life (QoL) outcomes from ICON7. Methods ICON7 is a randomised, multicentre, open-label phase 3 trial. Between Dec 18, 2006, and Feb 16, 2009, after a surgical procedure aiming to debulk the disease, women with Inter…

Adultmedicine.medical_specialtyBevacizumabDrug-Related Side Effects and Adverse ReactionsAntibodies Monoclonal HumanizedDisease-Free Survivallaw.inventionchemistry.chemical_compoundRandomized controlled trialQuality of lifelawInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAgedNeoplasm StagingOvarian NeoplasmsIntention-to-treat analysisbusiness.industryStandard treatmentArticlesMiddle Agedmedicine.diseaseCarboplatinSurgeryBevacizumabClinical trialTreatment OutcomeOncologychemistryQuality of LifeFemaleOvarian cancerbusinessmedicine.drugThe Lancet Oncology
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Radical vaginal trachelectomy (RVT) combined with laparoscopic lymphadenectomy: Prospective study of 225 patients with early-stage cervical cancer

2011

Objective: The aim of the study was to prove the surgical and oncological safety of radical vaginal trachelectomy (RVT) and laparoscopic lymphadenectomy for patients with early-stage cervical cancer who are seeking parenthood. Methods: A database of 225 patients with early-stage cervical cancer and intention to treat by RVT after laparoscopic lymphadenectomy was prospectively maintained. A total of 212 patients were treated according to the protocol. The procedure was preformed in a standardized manner, and life table analysis was applied. Results: In the cohort of patients treated according to protocol, 8 recurrences occurred and 4 patients died from recurrence. The median follow-up time w…

Adultmedicine.medical_specialtyUterine Cervical NeoplasmUrologyUterine Cervical NeoplasmsRadical vaginal trachelectomyAdenocarcinomaYoung AdultGynecologic Surgical ProceduresGynecologic Surgical ProcedureVaginal TrachelectomyEarly-stage cervical cancer; Fertility-preserving surgery; Radical vaginal trachelectomyMedicineHumansProspective StudiesStage (cooking)Prospective cohort studyLaparoscopic lymphadenectomyCervical cancerLaparoscopic lymphadenectomyIntention-to-treat analysisbusiness.industryMedicine (all)Fertility-preserving surgeryObstetrics and GynecologyPerioperativeMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSurgeryProspective StudieOncologyEarly-stage cervical cancerCohortVaginaCarcinoma Squamous CellLymph Node ExcisionFemaleLaparoscopybusinessHuman
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Ulipristal acetate versus leuprolide acetate for uterine fibroids

2012

A b s t r ac t Background The efficacy and side-effect profile of ulipristal acetate as compared with those of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are unclear. Methods In this double-blind noninferiority trial, we randomly assigned 307 patients with symptomatic fibroids and excessive uterine bleeding to receive 3 months of daily therapy with oral ulipristal acetate (at a dose of either 5 mg or 10 mg) or once-monthly intramuscular injections of leuprolide acetate (at a dose of 3.75 mg). The primary outcome was the proportion of patients with controlled bleeding at week 13, with a prespecified noninferiority margin of −20%. Results Uterine bleed…

Adultmedicine.medical_specialtyUterine fibroidsIntention to Treat AnalysiUrologyAdministration OralEndometriumInjections Intramuscularlaw.inventionchemistry.chemical_compoundYoung AdultEndometriumPrimary outcomeRandomized controlled trialDouble-Blind MethodlawUlipristal acetateSelective progesterone receptor modulatormedicineUterine NeoplasmUlipristalMenorrhagiaGynecologyIntention-to-treat analysisLeiomyomabusiness.industryObstetrics and GynecologyUterine bleedingUterine fibroids uterine leiomyomas uterine bleeding ulipristal acetate leuprolide acetate medical therapyGeneral MedicineNorpregnadieneMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E Ostetriciamedicine.anatomical_structurechemistryAmenorrheaFemalemedicine.symptomLeuprolidebusinessHuman
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El conocimiento y la intencionalidad didáctica en el uso de TIC del profesorado de educación física (Physical education teachers’ knowledge and educa…

2020

La formación digital tecnocéntrica del profesorado y el uso tradicional de las tecnologías de la información y de la comunicación (TIC), muestran la debilidad del discurso pedagógico frente al tecnológico, confirmando la limitada intencionalidad didáctica de los docentes al usar dichas tecnologías. En educación física se carece de instrumentos específicos para estudiar esa realidad. El objetivo del trabajo fue validar, por el método Delphi, un cuestionario para medir el nivel de conocimiento y la intencionalidad didáctica del profesorado de educación física al usar las TIC, atendiendo a la edad y al género. Posteriormente se aplicó el cuestionario a una muestra representativa de 155 docente…

Age and genderSchool teachersIntentionalityOrthopedics and Sports MedicinePhysical Therapy Sports Therapy and RehabilitationMetodo delphiPsychologyHumanitiesEducationPhysical educationRetos
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Study of the attitudes and future intentions of nursing students towards working with older people: an observational study

2021

Background: Older people are increasing in the world leading to the fact that many nursing students will work in geriatric care setting. It was also reported the lack of knowledge and interest in working with older people by many nursing students. Therefore, the aim of the study is to explore the attitudes, wills, and intentions for the care of older people from nursing students. Methods: A sample of 383 students (mean age between 17 and 24; females: 76.2%) was divided according to the year. A questionnaire and three scales investigating the attitude for working with older persons (Kogan, Aday-Campbell, Nolan scales) were administered. Simple correlations across the three scales and the com…

AgingGeriatric careAttitude of Health PersonneleducationIntention03 medical and health sciences0302 clinical medicineNursingSurveys and QuestionnairesHumansLack of knowledge030212 general & internal medicineOlder people.Knowledge of ageingAgedAged 80 and overHealth professionalsCross-Sectional StudiesAttitudeScale (social sciences)Observational studyFemaleStudents NursingNursing studentGeriatrics and GerontologyPositive attitudeOlder peoplePsychology030217 neurology & neurosurgeryGraduation
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Sympathetic blocks for visceral cancer pain management: A systematic review and EAPC recommendations.

2015

The neurolytic blocks of sympathetic pathways, including celiac plexus block (CPB) and superior hypogastric plexus block (SHPB) , have been used for years. The aim of this review was to assess the evidence to support the performance of sympathetic blocks in cancer patients with abdominal visceral pain. Only comparison studies were included. All data from the eligible trials were analyzed using the GRADE system. Twenty-seven controlled studies were considered. CPB, regardless of the technique used, improved analgesia and/or decrease opioid consumption, and decreased opioid-induced adverse effects in comparison with a conventional analgesic treatment. In one study patients treated with superi…

AnalgesicPainOpioidmedicine.nerveSympathetic blockSuperior hypogastric plexusMedicineHumansPain ManagementCancer painAdverse effectAutonomic Nerve BlockIntention-to-treat analysisbusiness.industryCeliac plexus blockVisceral painHematologyAnalgesics OpioidEuropeOncologySample size determinationAnesthesiaAbdominal NeoplasmsPractice Guidelines as Topicmedicine.symptomGeriatrics and GerontologybusinessCancer painSuperior hypogastric plexus blockAutonomic Nerve BlockCritical reviews in oncology/hematology
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Perceived benefits and constraints in vehicle automation: Data to assess the relationship between driver's features and their attitudes towards auton…

2019

This data article examines the association driver's features, perceptions and attitudes towards autonomous vehicles (AVs). The data was collected using a structured self-administrable and online-based questionnaire, applied to a full sample of 1205 Spanish drivers. The data contains 4 parts: the full set of bivariate correlations between study variables; descriptive statistics and graphical trends for each main study variable according to gender, age group and city/town size; and, finally, the dataset for further explorations in this regard. For more information, it is convenient to read the full article entitled “Perceived safety and attributed value as predictors of the intention to use a…

Applied psychologyAutonomous vehiclesPoison controlIntentionRoad SafetyBivariate analysislcsh:Computer applications to medicine. Medical informaticsOccupational safety and health03 medical and health sciences0302 clinical medicineInjury preventionPsychologySpanish driverslcsh:Science (General)Set (psychology)030304 developmental biology0303 health sciencesMultidisciplinaryDescriptive statisticsSeguretat viàriaHuman factors and ergonomicsVariable (computer science)PsicologiaAttitudeslcsh:R858-859.7PerceptionPsychology030217 neurology & neurosurgerylcsh:Q1-390Data in Brief
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