Search results for "Interaction"

showing 10 items of 5710 documents

Multivariate optimization of the hollow fibre liquid phase microextraction of muscimol in human urine samples.

2016

Abstract A liquid phase microextraction based on hollow fibre followed by liquid chromatographic determination was developed for the extraction and quantitation of the hallucinogenic muscimol from urine samples. Method applicability on polar hallucinogens was also tested on two alkaloids, a psychedelic hallucinogen, tryptamine and a polar amino acid, tryptophan which exists in its charged state in the entire pH range. A multivariate design of experiments was used in which a half fractional factorial approach was applied to screen six factors (donor phase pH, acceptor phase HCl concentration, carrier composition, stirring rate, extraction time and salt content) for their extent of vitality i…

TryptamineMaleAnalyteCentral composite designCalibration curveLiquid Phase MicroextractionClinical BiochemistryAnalytical chemistry010402 general chemistry01 natural sciencesBiochemistryAnalytical ChemistryMatrix (chemical analysis)chemistry.chemical_compoundYoung AdultLimit of DetectionHumansDetection limitAnalysis of VarianceChromatographyChemistryMuscimolHydrophilic interaction chromatography010401 analytical chemistryExtraction (chemistry)TryptophanReproducibility of ResultsCell BiologyGeneral MedicineModels TheoreticalReference StandardsTryptamines0104 chemical sciencesCalibrationMultivariate AnalysisJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
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Comparative Study of Different Column Types for the Separation of Polar Basic Hallucinogenic Alkaloids

2016

The number of hallucinogenic compounds that have been separated simultaneously by liquid chromatography is limited. This research aimed to identify a column(s) that can allow for separation of several hallucinogens. The extent of separation of seven polar hallucinogenic tryptamine and phenethylamine derived alkaloids containing a basic N atom that becomes protonated at low pH values were investigated on five reverse-based columns and one hydrophilic interaction liquid chromatography (HILIC) column. An RP-phenyl and a negatively charged fused core HILIC were identified and recommended as effective columns in this regard. This research is the first to introduce a HILIC column in separation of…

TryptaminePhenethylaminePolarity (physics)01 natural sciencesDiluenttetrahydrofuranchemistry.chemical_compoundmedicinehallucinogenOrganic chemistrypolar compoundsHILICAcetonitrilepsilocinTetrahydrofuranChromatography010405 organic chemistryHydrophilic interaction chromatography010401 analytical chemistryGeneral Chemistrymuscimol0104 chemical scienceschemistryPsilocinHallucinogenmedicine.drugSouth African Journal of Chemistry = Suid-Afrikaanse Tydskrif Vir Chemie
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Theoretical study of the interaction between sodium ion and a cyclopeptidic tubular structure.

2007

DFT calculations have been carried out to describe the pathway of a sodium ion along the stacking direction of a tubular structure set up by five cyclopeptidic units, which can be considered a suitable model of a hollow tubular structure of indefinite length. A lattice of points inside the tubular structure is defined and the DFT interaction energy values with a sodium ion are obtained. The data allow predicting a zigzag path of the ion inside the hosting structure. © 2007 Wiley Periodicals, Inc. J Comput Chem, 2007

Tubular aggregates alkaline ions DFTModels MolecularNanotubes PeptideNanotubeChemistrySodiumSodiumStackingGlycineMolecular Conformationchemistry.chemical_elementGeneral ChemistryInteraction energyMolecular physicsPeptides CyclicIonComputational MathematicsZigzagComputational chemistryLattice (order)ThermodynamicsComputer SimulationOligopeptidesJournal of computational chemistry
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Magnetic nanoparticles between electrodes of tunnel junction: anomalous tunnel conductance

2002

Abstract Magnetic particles of microscopic size can be created in the process of Ni, Fe and Co mechanically controllable break junctions fabrication and trapped between the electrodes by magnetic dipole forces. Tunneling between the protruding nanoparticle and the sample electrode shows clear distinctions from the usual junctions: heavy deviation of the current–distance I(z) dependence from the expected exponential behavior at electrode separations z below 4.0– 4.5 A and on numerous occasions a sudden jump-like decrease of the tunnel current at z≈1.5– 2.0 A . Possible mechanisms behind observed anomalies including the short-range magnetic exchange coupling are discussed.

Tunnel effectMaterials scienceCondensed matter physicsTunnel junctionExchange interactionElectrodeMagnetic nanoparticlesConductanceElectrical and Electronic EngineeringCondensed Matter PhysicsMagnetic dipoleQuantum tunnellingElectronic Optical and Magnetic MaterialsPhysica B: Condensed Matter
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An Augmented Campus Design for Context-aware Service Provision

2005

This paper deals with the design of a multi-modal system for pervasive context-aware service provision and human-environment interaction in augmented environments by the use of Personal Digital Assistants (PDA) or SmartPhones. The system enables mobile devices and remote displays to perform as interaction devices with pervasive applications which run on a dynamically composed server network. Visual interaction for service setup and provision are driven by appropriate graphical interfaces and XML-based protocols, which are dynamically composed according to the type of service and to the user current position by means of a mobile agent-based framework. The paper discusses both protocols, hard…

Type of serviceService (systems architecture)MultimediaComputer scienceHuman–computer interactionService discoverySmart environmentMobile agentContext (language use)Software systemcomputer.software_genreMobile devicecomputer
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Utilizing digital tools to support face-to-face care : Examining uptake within the practices of Australian psychologist

2020

Societal adoption of mobile phones and other digital devices, and the resulting widespread digital literacy, allows for new possibilities in approaching and supporting faceto-face therapy. In this study, we examined the application of digital communication tools and media within therapeutic care by 33 psychologists across Australia. Uses of digital technologies were analyzed with a focus on both the approaches applied within face-to-face therapy sessions and those occurring as an adjunct to these sessions. In contrast to online counseling, established upon a foundation of digital technologies, the study results indicate that the use of technology in face-to-face therapy is still emerging bu…

TypologyKnowledge managementterveyspalvelutSocial PsychologyScope (project management)business.industryComputer scienceCommunicationdigital healthface-to-face carelangaton tekniikkasmartphoneDigital healthOnline counselingälyHuman-Computer InteractionFace-to-faceface-to-face therapymobile technologyInformation and Communications TechnologyhoitomenetelmätMobile technologydigital literacybusinessDigital literacy
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NMR structure of a non-conjugatable, ADP-ribosylation associated, ubiquitin-like domain from Tetrahymena thermophila polyubiquitin locus.

2019

Abstract Background Ubiquitin-like domains (UbLs), in addition to being post-translationally conjugated to the target through the E1-E2-E3 enzymatic cascade, can be translated as a part of the protein they ought to regulate. As integral UbLs coexist with the rest of the protein, their structural properties can differ from canonical ubiquitin, depending on the protein context and how they interact with it. In this work, we investigate T.th-ubl5, a UbL present in a polyubiquitin locus of Tetrahymena thermophila, which is integral to an ADP-ribosyl transferase protein. Only one other co-occurrence of these two domains within the same protein has been reported. Methods NMR, multiple sequence al…

UBL DOMAINspektroskopiaGTPasePARKINBiochemistryPROTEIN BACKBONEACTIVATIONprotein-protein interaction0302 clinical medicineProtein-protein interactionUbiquitinmolekyylidynamiikkaNMR-spektroskopiaPolyubiquitinADP Ribose Transferases0303 health sciencesMultiple sequence alignmentbiologyFERM domainChemistryTetrahymenastructure-function relationshipFAMILYCell biologyRECEPTORSPost-translational modificationSignal TransductionBiophysicsSequence alignmentMolecular Dynamics SimulationUbiquitin-like domainsMECHANISMSProtein–protein interactionTetrahymena thermophila03 medical and health sciencesNMR spectroscopyADP-RibosylationubikitiinitMolecular BiologyNuclear Magnetic Resonance Biomolecular030304 developmental biologyMolecular dynamics simulationsStructure-function relationshipmolecular dynamics simulationsbiology.organism_classificationProtein Structure Tertiarypost-translational modificationProteasomeMOLECULAR-DYNAMICSbiology.protein1182 Biochemistry cell and molecular biologyproteiinitGTPASEProtein Processing Post-Translational030217 neurology & neurosurgeryFERM DOMAINBiochimica et biophysica acta. General subjects
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Unraveling the complex trait of low temperature adaptation in the wine yeast Saccharomyces cerevisiae

2016

1. Introducción Se cree que las uvas fueron domesticadas entre el Mar Negro e Irán durante el periodo del 7000-4000 aC. Las primeras evidencias de elaboración de vino provienen de la presencia de ácido tartárico en un tarro antiguo que data de 5400 - 5000 aC en el yacimiento neolítico de Tepe en Mesopotamia y de los restos de la extracción del zumo de uva en el yacimiento neolítico de Dikili Tash en Grecia (5000 aC). La colonización de los romanos extendió la elaboración del vino por todo el Mediterráneo; en el 500 aC el vino ya se producía en Italia, Francia, España, Portugal y el norte de África. Posteriormente también fue extendido a los Balcanes, Alemania y otras partes del norte de Eur…

UNESCO::CIENCIAS DE LA VIDAmolecular biologyoxidative stress responseyeastlow temperaturewinequantitative trait analysis:CIENCIAS DE LA VIDA [UNESCO]phenotype-genotype interaction
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The role of social processes and decision making on the psychobiological response to social stress

2018

Los humanos, a diario, se enfrentan a diversas interacciones sociales, que pueden ser interpretadas como retos o como amenazas en función del contexto y del individuo que las enfrenta. Es por ello, que el cuerpo humano acaba activando sus mecanismos fisiológicos y conductuales en función de cómo interpreta está situación. Durante toda esta interpretación los humanos deciden un patrón de conducta que les lleva a tomar un tipo de decisiones u otras para adaptarse a estas interacciones sociales. Es por ello que la toma de decisiones puede ser una variable de estudio importante a lo largo de toda una interacción social, tanto como decidimos en función de la interacción y la respuesta fisiológic…

UNESCO::CIENCIAS DE LA VIDA::Neurocienciastestosteroneheart rate variabilitysocial interactions:CIENCIAS DE LA VIDA::Neurociencias [UNESCO]:PSICOLOGÍA::Psicología experimental::Psicología fisiológica [UNESCO]UNESCO::PSICOLOGÍA::Psicología experimental::Psicología fisiológicacortisoldecision making
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Du verbe instrumental dans la musique subsaharienne

2021

Sub-Saharan music results from the spoken language/instrumental language relation, directed by an oral culture. In this culture, these languages transmit ? beyond their singularities ? messages thanks to either a coded signal known by the linguistic community or previously defined among a group of individuals, or is used as a true meta-language copied on the articulated and usual language used every day. Here, an instrumental musical speech can then imitate and reproduce the tonal inflexions of the language to make its matter understandable. This fact is the natural result of a strong interaction and interrelation between the spoken language and the music as well as the conception that the …

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASan instrumental musical speech can then imitate and reproduce the tonal inflexions of the language to make its matter understandable. This fact is the natural result of a strong interaction and interrelation between the spoken language and the music as well as the conception that the Africans of South Sahara have of it. This concept underlying the very tight link between the musical fact and the Worddetermine and contribute to the distinctive goals of the speech? These are some of the major questions to which I the author try to bring elements of answers to clear up this subject. 145 1642386-8260 13268 ItamarApollinaire Sub-Saharan music results from the spoken language/instrumental language relation:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]territorios para el arte 590908 2021 7 8182063 Du verbe instrumental dans la musique subsaharienne Anakesa Kululuka [revista de investigación musical]these languages transmit ? beyond their singularities ? messages thanks to either a coded signal known by the linguistic community or previously defined among a group of individualsdirected by an oral culture. In this culturecontextual and expressive parameters that underliethe musical act then carries a communicative importance equal to the one in a spoken language. What concept rules such a language? What treatment is language subjected to in the affectation of its components in the musical discourse of to the instrumental Word and vice versa? What are the technicalor is used as a true meta-language copied on the articulated and usual language used every day. Hererevista de investigación musical: territorios para el arte 590908 2021 7 8182063 Du verbe instrumental dans la musique subsaharienne Anakesa Kululuka
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