Search results for "Intermolecular"

showing 10 items of 396 documents

Synthesis of Pyrrolidin-2-ones and of Staurosporine Aglycon (K-252c) by Intermolecular Michael Reaction

1999

Indolo[2,3-a]pyrrolo[3,4-c]carbazoles were isolated from nature, e.g., from low plants, especially fungi, as structurally rare natural substances. Responsible for naming and also the most important representative of this type is staurosporine (1), isolated from Streptomyces staurosporeus, and its aglycon (2), also known as staurosporinone or K-252c. 3,4-Disubstituted pyrrolidin-2-ones, a group of compounds with many interesting biological properties are related to staurosporinone. The most important property is the inhibition of protein kinase C (PKC), so that this antiproliferative agent can interfere with the cell cycle. The synthetic strategy, developed by us, allows the synthesis of pyr…

StaurosporinoneStereochemistryOrganic ChemistryIntermolecular forceEnantioselective synthesisCombinatorial chemistrychemistry.chemical_compoundchemistryNitroLactammedicineMichael reactionStaurosporineProtein kinase Cmedicine.drugThe Journal of Organic Chemistry
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Molecular materials with conducting and magnetic properties based on ET and [ M(tdas)2]x-dithiolenes

2004

Two hybrid molecular materials showing a combination of magnetic and conducting properties, the charge-transfer (ET) 2 [Fe(tdas) 2 ] (1) and (ET)Ni(tdas) 2 (2), (ET=bis(ethylenedithio) tetrathiafulvalene; M=Fe, Ni; tdas=l,2,5-thiadiazole-3,4-dithiolate) salts, are characterized by vibrational (IR and Raman) and UV-VIS-NIR spectroscopies. These studies have proved to be effective and diagnostic tools in identifying the oxidation state (partial or integer) and the packing pattern (dimers or segregated stacks) of the ET donor only, since no v(C=C) group vibration sensitive to the charge of M(tdas) 2 complexes has been observed. This is ascribed to the extensive electron-delocalization inside t…

StereochemistryChemistryIntermolecular forceGeneral Physics and AstronomyRing (chemistry)Extended Hückel methodCrystallographysymbols.namesakechemistry.chemical_compoundElectrical resistivity and conductivityOxidation stateMolecular vibrationsymbolsRaman spectroscopyTetrathiafulvaleneJournal de Physique IV (Proceedings)
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Über antimon-haltige heterocyclen

1980

Abstract p -Nitrophenyl- and p -tolyl-oxadithia- and trithiastibocanes have been synthesized from the respective aryldichlorostibane and dithiole. The compounds have been characterised by means of 13 C NMR and vibrational spectra (ν(SBS 2 ) 350–320 cm −1 ). The crystal structure of p -nitrophenyltrithiastibocane has been determined ( R = 0.042). The eight-membered ring exhibits a boat-chair conformation. Single-bond distances of SbC and SbS (219, 244 and 245 pm), a 1,5-transannular Sb⋯S interaction (319 pm), and Sb⋯S and Sb⋯O (339 and 353 pm) intermolecular contacts, result in a six-coordinated Sb III (ψ-monocapped octahedral) species. The two additional Sb⋯S distances are in accordance w…

StereochemistryChemistryOrganic ChemistryIntermolecular forceDithiolEthanedithiolCrystal structureNuclear magnetic resonance spectroscopyCarbon-13 NMRDihedral angleRing (chemistry)BiochemistryInorganic Chemistrychemistry.chemical_compoundCrystallographyOctahedronX-ray crystallographyMass spectrumMaterials ChemistryProton NMRSingle bondMoleculePhysical and Theoretical ChemistryJournal of Organometallic Chemistry
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Synthesis and crystal structure of {Rh2(O2CCH3)4·P(o-CH3OH6H4)Ph2}2. A novel dirhodium(II) monoadduct with intermolecular μ-oxo interactions

1997

Abstract We have investigated the reaction of dirhodium tetraacetate with the phosphine P( o -CH 3 OH 6 H 4 )Ph 2 (P) under different experimental conditions. From these reactions we have been able to isolate the dirhodium tetraacetate phosphine mono-adduct. The crystal structure shows that in the solid state this compound forms a centrosymmetric dimer of the dimer, {Rh 2 (O 2 CCH 3 ) 4 ·P(0-CH 3 OC 6 H 4 )Ph 2 } 2 , in which we oxygen atom from one acetate group in one Rh 2 (O 2 CCH 3 ) 4 ·P unit is axially coordinating one Rh atom on another Rh 2 (O 2 CCH 3 ) 4 · P unit (Rh⋯) 2.347(3) A intermolecular versus Rh⋯O 2.455(3) A intermolecular), and vice versa. The RhRh bond distance is 2.414…

StereochemistryDimerIntermolecular forceSolid-stateCrystal structureMedicinal chemistryDirhodium tetraacetateInorganic ChemistryBond lengthchemistry.chemical_compoundchemistryAtomMaterials ChemistryPhysical and Theoretical ChemistryPhosphineInorganica Chimica Acta
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Intramolecular versus intermolecular exchange pathways in the binuclear complex [Cu2(H2tea)2(4,4′-bipy)](ClO4)2·3H2O (H3tea=triethanolamine and 4,4′-…

2001

Abstract The binuclear copper(II) complex of formula [Cu2(H2tea)2(4,4′-bipy)](ClO4)2·3H2O (1) (H3tea=triethanolamine and 4,4′-bipy=4,4′-bipyridine) has been isolated and characterized by X-ray diffraction. Its structure consists of dinuclear [Cu2(H2tea)2(4,4′-bipy)]2+ cations, uncoordinated perchlorate anions and crystallization water molecules. Each copper atom exhibits a trigonal-bipyramidal environment with the three triethanolamine-oxygen atoms building the equatorial plane, and the triethanolamine-nitrogen and one of the 4,4′-bipy nitrogen atoms defining the three-fold axis. The 4,4′-bipy molecule acts as a bismonodentate bridging ligand, the copper–copper separation across it being 11…

StereochemistryIntermolecular forceBridging ligandCrystal structure44'-BipyridineInorganic ChemistryPerchloratechemistry.chemical_compoundCrystallographychemistryTriethanolamineIntramolecular forceMaterials ChemistrymedicineMoleculePhysical and Theoretical Chemistrymedicine.drugPolyhedron
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Synthesis and structure of charge transfer salts of tetrathiafulvalene (TTF) and tetramethyl-TTF with 2,4,7-trinitro and 2,4,5,7-tetranitro-9-fluoren…

2009

Charge transfer salts of tetrathiafulvalene (TTF) and tetramethyltetrathiafulvalene (TMTTF) with the organic acceptors 2,4,7-trinitro-9-fluorenone and 2,4,5,7-tetranitro-9-fluorenone have been prepared and characterized. The compounds (TTF)(TENF) (1), (TTF)3(TRNF)2 (2) and (TMTTF)(TRNF) (3) contain mixed stacks of alternating TTF and nitrofluorenone units. Surprisingly, the degree of charge transfer that occurs in these salts is not controlled solely by the redox potentials of the building blocks, but apparently also by the most effective intermolecular interactions in the solid, as determined from the crystal struc- tures obtained. These three compounds exhibit poor electron delocalization…

StereochemistryMechanical EngineeringIntermolecular forceMetals and AlloysElectron delocalizationCharge (physics)Crystal structureCondensed Matter PhysicsRedoxElectronic Optical and Magnetic MaterialsCrystalchemistry.chemical_compoundCrystallographychemistryMechanics of MaterialsMaterials ChemistryDiamagnetismTetrathiafulvaleneSynthetic Metals
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Four-, five- and six-coordinated Zn-II complexes of OH-containing ligands: Syntheses, structure and reactivity

2002

Four-, five- and six-coordinated complexes of Zn-II with OH-rich molecules possessing an ONO binding core were synthesized, characterized and their structures were established by single-crystal X-ray diffraction, The corresponding metal ion geometries were found to be distorted tetrahedral, square pyramidal and octahedral, respectively. The complexes exhibit interesting lattice structures such as layered and corrugated sheets owing to the presence of a number of weak intermolecular interactions. The five-coordinated, water-bound Zn-II complex was studied because of its putative hydrolysis property towards p-nitrophenyl acetate. (C) Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.

StereochemistryMetalloenzymesCrystal structureInorganic ChemistryX-Ray DiffractionCrystal-StructuresElectrochemistryMoleculeReactivity (chemistry)IonMonooxovanadium(V)ChemistryHydrogen bondIntermolecular forceCarbonic-AnhydraseNO LigandsHydrogen BondsSquare pyramidal molecular geometryCrystallographyVanadium(V) ComplexesRecognitionZincZinc EnzymesOctahedronX-ray crystallographyDerivativesModelIndraStra Global
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Inclusion complexes of Cethyl-2-methylresorcinarene and pyridine N-oxides: breaking the C–I⋯−O–N+ halogen bond by host–guest complexation

2016

C ethyl-2-Methylresorcinarene forms host–guest complexes with aromatic N-oxides through multiple intra- and intermolecular hydrogen bonds and C–H⋯π interactions. The host shows conformational flexibility to accommodate 3-methylpyridine N-oxide, while retaining a crown conformation for 2-methyl- and 4-methoxypyridine N-oxides highlighting the substituent effect of the guest. N-Methylmorpholine N-oxide, a 6-membered ring aliphatic N-oxide with a methyl at the N-oxide nitrogen, is bound by the equatorial −N–CH3 group located deep in the cavity. 2-Iodopyridine N-oxide is the only guest that manifests intermolecular N–O⋯I–C halogen bond interactions, which are broken down by the host resulting i…

StereochemistrySubstituentmacromolecular substancesCrystal structure010402 general chemistryRing (chemistry)01 natural sciencespyridine N-oxideschemistry.chemical_compoundPyridineWATERGeneral Materials ScienceCRYSTAL-STRUCTURESta116Cethyl-2-methylresorcinareneCOORDINATIONHalogen bondPACKINGta114010405 organic chemistryHydrogen bondIntermolecular forceRECOGNITIONGeneral ChemistryETHYL RESORCINARENECondensed Matter PhysicsMETHYLRESORCINARENE0104 chemical sciencesCrystallographySOLID-STATEchemistryhost–guest complexationMETALMOLECULAR CAPSULEShalogen bondSingle crystalCrystEngComm
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Self-assembly of 1D- and 3D-networks through non-coordination intermolecular forces: synthesis and crystal structures of copper(I) complexes based on…

2007

Reaction of [Cu2(H3CCN)2(μ-pydz)3][PF6]2 (1) with an excess of pyridazine or phthalazine yielded the novel dinuclear complexes [Cu2(μ-pydz)3(pydz)2][PF6]2 (2) and [Cu2 (μ- pydz)(μ-phtz)2(phtz)2][PF6]2 (5), respectively. Depolymerisation of the coordination polymer 1 ∞ {[Cu(μ-pydz)2][PF6]} (3) in dichloromethane by addition of an excess of benzo[c]cinnoline afforded the dinuclear copper(I) salt [Cu2(μ-pydz)2(pydz)2(benzo[c]cinnoline)2][PF6]2 (4). Furthermore, a new route for the preparation of bis(benzonitrile)tris(μ-phthalazine)dicopper(I) bis(trifluoromethanesulfonate), [Cu2(C6H5CN)2(μ-phtz)3][CF3SO3]2 (7), was established from {[Cu(CF3SO3)]2 ・C6H5Me}, phthalazine and benzonitrile via the …

Stereochemistrychemistry.chemical_elementphthalazineCrystal structure010402 general chemistry01 natural sciencesPyridazinechemistry.chemical_compound[CHIM.COOR]Chemical Sciences/Coordination chemistryCinnolineComputingMilieux_MISCELLANEOUS010405 organic chemistryIntermolecular force[ CHIM.COOR ] Chemical Sciences/Coordination chemistryGeneral Chemistrybenzo[c]cinnolineself-assemblyCopper0104 chemical sciencescopper(I)CrystallographyBenzonitrilepyridazinechemistryPhthalazineTrifluoromethanesulfonate
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Overcoming Steric Hindrance in Aryl‐Aryl Homocoupling via On‐Surface Copolymerization

2019

On-surface synthesis is a unique tool for growing low-dimensional carbon nanomaterials with precise structural control down to the atomic level. This novel approach relies on carefully designed precursor molecules, which are deposited on suitable substrates and activated to ultimately form the desired nanostructures. One of the most applied reactions to covalently interlink molecular precursors is dehalogenative aryl-aryl coupling. Despite the versatility of this approach, many unsuccessful attempts are also known, most of them associated to the poor capability of the activated precursors to couple to each other. Such failure is often related to the steric hindrance between reactants, which…

Steric effectsArylIntermolecular force02 engineering and technologyConjugated system010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesCombinatorial chemistryAtomic and Molecular Physics and Optics0104 chemical sciencesNanomaterialschemistry.chemical_compoundAdsorptionchemistryCovalent bond540 ChemistryCopolymer570 Life sciences; biologyPhysical and Theoretical Chemistry0210 nano-technologyChemPhysChem
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