Search results for "Intestin"
showing 10 items of 2215 documents
Exactitud diagnóstica de la resonancia magnética preoperatoria en la determinación de la extensión y grado de actividad inflamatoria de la enfermedad…
2014
Introducción: La correcta identificación de la localización y cuantificación de la actividad inflamatoria de las lesiones de la enfermedad de Crohn es necesaria para establecer cuál es el manejo más adecuado para cada paciente Métodos: Se trata de un estudio prospectivo observacional consecutivo que abarca un periodo de estudio de 30 meses. El diagnóstico se realiza según los criterios de Lennard-Jones y la clasificación de Montreal. Se realizó una resonancia magnética mediante enterografía, con el mismo protocolo y secuencias, en los tres meses previos a la cirugía. Se determinaron las características radiológicas de las lesiones, se obtuvo el índice de actividad de la resonancia magnética…
cytokines in the inflammatory response of the ascidian ciona intestinalis
2015
The Ciona intestinalis inflammatory response to several irritants have been demonstrated to be composed of a complex set reaction. The cellular reactions involve hemocyte infiltration, hemocyte and epidermis activities, vacuolization, cell disruption, while cell products can contribute to form capsule components and/or cause a wound. In this response the involvement of the pharynx, as the main immune-competent organ, has been disclosed by lipopolysaccharide (LPS) challenge that upregulates innate immunity genes. In vertebrate cytokines modulate the balance between humoral and cell-based immune responses, and they regulate the maturation, growth, and responsiveness of cell populations that h…
Stercorary aseptic peritonitis due to diastatic caecal perforation: Computed tomography findings
2006
Caecal perforation is a complication secondary to colon obstruction. It may present with insidious clinical features and may be associated with chronic constipation. The event may become severe due to the peritonitic development. We present a case of caecal perforation associated with sub-occlusive carcinoma of the left colon and hypotonic colitis caused by chronic lavative abuse, demonstrated with Computed Tomography.
Parasitación intestinal por unicelulares eucariotas en una población con obesidad mórbida: implicaciones clínico-metabólicas
2022
La obesidad es una enfermedad grave y multidimensional que, en la actualidad, ha alcanzado dimensiones pandémicas. Muchos son los mecanismos fisiopatológicos propuestos para intentar explicar el marcado aumento de su incidencia, y que se han orientado a hallar nuevas dianas terapéuticas con las que combatirla. Clásicamente se han señalado los factores ambientales propios del estilo de vida occidental (como la alimentación hipercalórica y el sedentarismo) como relevantes en el desarrollo de esta enfermedad; sin embargo, nuevas evidencias apuntan hacia que también podrían jugar un papel importante elementos infecciosos del medio, con repercusiones tanto perjudiciales como protectoras sobre el…
The intestinal ecosystem and probiotics
2016
The term "probiotic" comes from the greek "pro bios" and means "pro life": Nowadays, an increasing number of pharmaceutical preparations and functional foods are enriched with probiotics and for the patients it is increasingly important to receive information needed to know how to orient in the choice. The benefits from probiotics are many and include the modulation of the intestinal microflora (stimulation of beneficial bacteria and inhibition of pathogens), the support of bowel function and the stimulation of the immune system. This broad spectrum of beneficial effects to maintain efficient the intestinal ecosystem. Therefore, probiotics are an useful tool to prevent the formation of diso…
Laika ietekme ārkārtas gastroendoskopijas veikšanā uz ārstēšanas iznākumu nevarikozas augšējas GI asiņošanas gadījumā
2018
Darba nosaukums: Laika ietekme ārkārtas gastroendoskopijas veikšanā uz ārstēšanas iznākumu nevarikozas augšējās GI asiņošanas gadījumā. Ievads: Akūta nevarikoza augšējā gastrointestinālā trakta asiņošana ir nopietna medicīniska patoloģija, kas var veicināt tālāku veselības pasliktināšanos un pat nāvi. Šī iemesla dēļ ir svarīgi analizēt agrīnas un vēlīnas ārkārtas endoskopijas ietekmi uz ārstēšanas iznākumu nevarikozas augšējās GI asiņošanas gadījumos. Darba mērķis: Mērķis ir izpētīt, vai agrīna endoskopisko izmeklējumu veikšana pacientam samazina negatīvu iznākumu riskus. Materiāli un metodes: Darbs ir veikts kā retrospektīvs kohortas pētījums. Dati tika ievākti no 2010. līdz 2017. gadam. P…
Systematic review: the presenting international normalised ratio (INR) as a predictor of outcome in patients with upper nonvariceal gastrointestinal …
2011
Aliment Pharmacol Ther 2011; 33: 1010–1018 Summary Background The prognostic value of an elevated international normalised ratio (INR) as part of initial risk stratification in nonvariceal upper gastrointestinal bleeding (NVUGIB) remains poorly characterised. Aim To assess the usefulness of the initial INR in patients with NVUGIB. Method After a systematic review, we included the presenting INR and other validated prognosticators in multivariable models predicting rebleeding and mortality. Data are reported as odd ratios and 95% confidence intervals. Results Only two of 769 candidate studies were useful, but reported disparate, highly selected NVUGIB patients with varying threshold init…
Chromogranin A in the Mammalian Merkel Cell: Cellular and Subcellular Distribution
1989
Chromogranin-A (CGA), which accounts for more than half the soluble matrix protein in secretory granules of various neuroendocrine cells, has a wide spectrum of potential biological roles and is considered an important marker of the diffuse neuroendocrine system (DNES). Light and electron microscopic immunohistochemistry of mammalian skin revealed that Merkel cells are exclusively CGA-immunoreactive (ir) and that the immunoreaction is localized in the secretory granules. This finding supports the classification of the Merkel cell as a member of the DNES. The CGA immunoreactivity was restricted to Merkel cells of pigs and humans. In human embryonic skin, CGA was expressed in Merkel cells as …
The glucagon-like Peptide-2
2011
Multiple peptide hormones produced within the gastrointestinal system act also in the central nervous system and aid in the regulation of energy homeostasis and metabolism. The list of these peptides is progressively increasing and includes glucagon-like peptide 2 (GLP-2) as an anorexigenic factor. GLP-2 is released from enteroendocrine L-cells following food intake and its principal target is represented by the gastrointestinal tract. GLP-2 has been shown to be an important intestinotrophic factor that stimulates epithelial cell proliferation and inhibits apoptosis. GLP-2 increases intestinal blood flow and the activity and expression of epithelial brush-border digestive enzymes and nutrie…
Review article: a comparison of glucagon-like peptides 1 and 2.
2013
Summary Background Recent advancements in understanding the roles and functions of glucagon-like peptide 1 (GLP-1) and 2 (GLP-2) have provided a basis for targeting these peptides in therapeutic strategies. Aim To summarise the preclinical and clinical research supporting the discovery of new therapeutic molecules targeting GLP-1 and GLP-2. Methods This review is based on a comprehensive PubMed search, representing literature published during the past 30 years related to GLP-1 and GLP-2. Results Although produced and secreted together primarily from L cells of the intestine in response to ingestion of nutrients, GLP-1 and GLP-2 exhibit distinctive biological functions that are governed by t…