Search results for "Is-a"

showing 10 items of 60 documents

Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancer.

2021

doi: 10.1053/j.gastro.2021.04.042 Background & Aims Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder associated with an elevated risk of colorectal cancer (CRC). IBD-associated CRC (IBD-CRC) may represent a distinct pathway of tumorigenesis compared to sporadic CRC (sCRC). Our aim was to comprehensively characterize IBD-associated tumorigenesis integrating multiple high-throughput approaches, and to compare the results with in-house data sets from sCRCs. Methods Whole-genome sequencing, single nucleotide polymorphism arrays, RNA sequencing, genome-wide methylation analysis, and immunohistochemistry were performed using fresh-frozen and formalin-fixed tissue sam…

0301 basic medicineEpigenomicsMaleColorectal cancerDNA Mutational AnalysisPHENOTYPEmedicine.disease_causeEpigenesis GeneticPATHWAY0302 clinical medicineMUTATIONAL PROCESSESDRIVERSTumor MicroenvironmentFinlandOligonucleotide Array Sequence AnalysisAged 80 and overDNA methylationMETHYLATIONGastroenterologyWnt signaling pathwaytulehdukselliset suolistosairaudetHigh-Throughput Nucleotide SequencingMiddle AgedDNA-metylaatio3. Good healthCell Transformation NeoplasticepigenetiikkaDNA methylationCONSENSUS MOLECULAR SUBTYPES030211 gastroenterology & hepatologyFemaleconsensus molecular subtypeKRASgeneettiset tekijätAdultEpithelial-Mesenchymal TransitionINTESTINAL INFLAMMATIONConsensus Molecular Subtype3122 Cancersepithelial-mesenchymal transitioncolorectal cancersuolistosyövätBiology3121 Internal medicinePolymorphism Single Nucleotide03 medical and health sciencesinflammatory bowel diseaseCOLONAXIN2medicineBiomarkers TumorHumansEpithelial–mesenchymal transitionEpigeneticsneoplasmsSIGNATURESAgedNeoplasm StagingColorectal CancerHepatologyWhole Genome SequencingSequence Analysis RNAGene Expression ProfilingInflammatory Bowel DiseaseDNA Methylationmedicine.diseaseInflammatory Bowel DiseasesEVOLUTIONdigestive system diseases030104 developmental biologyMutationCancer research3111 BiomedicineColitis-Associated NeoplasmsNeoplasm GradingCarcinogenesisTranscriptomeGastroenterology
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FT-IR spectroscopy : A powerful tool for studying the inter- and intraspecific biodiversity of cultivable non-Saccharomyces yeasts isolated from grap…

2016

International audience; The efficiency of the FT-IR technique for studying the inter- and intra biodiversity of cultivable non-Saccharomyces yeasts (NS) present in different must samples was examined. In first, the capacity of the technique FF-IR to study the global diversity of a given sample was compared to the pyrosequencing method, used as a reference technique. Seven different genera (Aureobasidium, Candida, Cryptococcus, Hanseniaspora, Issatchenkia, Metschnikowia and Pichia) were identified by FT-IR and also by pyrosequencing. Thirty-eight other genera were identified by pyrosequencing, but together they represented less than 6% of the average total population of 6 musts. Among the sp…

0301 basic medicineIdentification[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionBiodiversityWineHanseniasporaSaccharomycesMicrobial ecology[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyYeastsSpectroscopy Fourier Transform InfraredVitisDNA FungalMycological Typing TechniquesPhylogenyCandidaIntragenomic variationbiologySp-nov.Pyrolysis mass-spectrometryPyrosequencingBiodiversityCandida zemplininaYeast in winemaking[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyFT-IR spectroscopyMetschnikowiaAlcoholic fermentationMicrobiology (medical)food.ingredientWine yeast030106 microbiologyMicrobiologyIntraspecific competitionCandida-zemplininaSaccharomyces03 medical and health sciencesfoodBotanyRNA Ribosomal 18SMolecular BiologyBase SequenceComputational BiologySequence Analysis DNAbiology.organism_classificationGreen lacewingsStrain typingPyrosequencingTransform-infrared-spectroscopy[SDV.AEN]Life Sciences [q-bio]/Food and NutritionBotrytis-affected wine
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Stinging nettle (Urtica dioica L.) as a functional food additive in egg pasta: Enrichment and bioaccessibility of Lutein and β-carotene

2018

Abstract The use of stinging nettles as an ingredient in egg pasta has been evaluated with respect to food enrichment with carotenoids. Bioaccessibility of lutein and β-carotene has been estimated by dynamic simulation of the digestion process, with particular attention to duodenum and colon stages. Higher bioaccessibility for the two carotenoids occurs between 2 and 24 h of colonic fermentation and it is around 35% for lutein and 10% for β-carotene. However, the results reveal that the food matrix has a significant role in carotenoid release during the digestion process. In general, nettle enriched pasta has a lower carotenoid bioaccessibility than dietary supplement at duodenum and after …

0301 basic medicineLuteinCarotenoid-enriched foodmedicine.medical_treatmentDietary supplementLutein β-Carotene Stinging nettle Carotenoid-enriched food Bioaccessibility HPLC-UV/Vis-APCI-MS/MSMedicine (miscellaneous)Bioaccessibilityβ-CaroteneStinging nettle01 natural sciencesNOHPLC-UV/Vis-APCI-MS/MS03 medical and health sciencesIngredientchemistry.chemical_compoundFunctional foodmedicineTX341-641Food scienceUrtica dioicaCarotenoidchemistry.chemical_classification030109 nutrition & dieteticsNutrition and DieteticsNutrition. Foods and food supplyLutein010401 analytical chemistryCarotenefood and beverages0104 chemical scienceschemistryDigestionFood ScienceJournal of Functional Foods
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Arvovallan ja vakauden puolesta : Jugoslavian hajoaminen Ranskan parlametin keskusteluissa vuosina 1991-1995

2013

Tässä tutkimuksessa perehdytään niihin tulkintoihin, joita Ranskan parlamentissa esitettiin vuosina 1991–1995 Jugoslavian hajoamista seuranneeseen konfliktiin liittyen sekä siihen, miten tulkinnoista muodostui Ranskan sisäpoliittinen kysymys. Hallitukselle esitetyistä kysymyksistä on muodostunut tärkeä parlamentaarinen instrumentti, jonka avulla parlamentaarikoiden on mahdollista pakottaa haluamansa aiheet osaksi valtiopäivätyöskentelyä. Ensisijaisen tutkimusaineiston muodostavatkin Ranskan parlamentin istuntopöytäkirjoista löytyvät hallitukselle esitetyt kysymykset, joita täydentävät (entistä) Jugoslaviaa koskevat hallituksen tiedonannot. Aineistoa lähestytään noudattamalla Quentin Skinner…

1990-lukuJugoslaviaPohjois-Atlantin liittoparlamentitkonfliktitRanskaYhdistyneet kansakunnatEuroopan unioni
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Clinical evaluation of pancreatitis-associated protein as a serum marker of hepatocellular carcinoma: Comparison with α-fetoprotein

1998

This study evaluated the significance of serum pancreatitis-associated protein (PAP) assay, as a marker of hepatocellular carcinoma (HCC), in comparison and combined with α-fetoprotein (AFP) assay. Sixty-five patients with HCC, 59 with liver cirrhosis (LC) and 68 asymptomatic controls (C) were studied. PAP and AFP values significantly increased from C to LC and HCC group (p < 0.0001). The area under receiver-operating characteristic (ROC) curve for the two markers was not statistically different. At 100% specificity, ROC analysis gave a cut-off level for AFP of 166 IU/l with 40% sensitivity, and a cut-off level of 240 µg/l for PAP with 23% sensitivity. Diagnostic accuracy of combined AFP…

AdultMaleCancer ResearchPathologymedicine.medical_specialtyCirrhosisCarcinoma HepatocellularPancreatitis-Associated ProteinsAsymptomaticSensitivity and SpecificityAntigens NeoplasmBiomarkers TumorMedicineHumansLectins C-TypeneoplasmsTumor markerAgedbusiness.industryLiver NeoplasmsGeneral MedicineMiddle Agedmedicine.diseasedigestive system diseasesLogistic ModelsOncologyHepatocellular carcinomaPancreatitisFemalealpha-Fetoproteinsmedicine.symptombusinessClinical evaluationSerum markersAcute-Phase Proteins
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Pancreatitis-associated protein in patients with celiac disease: Serum levels and immunocytochemical localization in small intestine

1997

Since PAP is a stress protein expressed in human pancreas during pancreatitis but also constitutively synthesized in the small intestine, we looked whether its expression would be altered in patients with celiac disease. Serum PAP concentrations were determined consecutively in 54 patients with celiac disease on a free diet (group A), in 47 patients with celiac disease on a gluten-free diet (group B), in 22 patients with other intestinal pathologies but with normal intestinal mucosa (group C), in 14 patients with retarded growth, no gastrointestinal disease and normal intestinal mucosa (group D), and in 17 controls (group E). Serum PAP levels (ng/ml) were significantly higher in group A (12…

Adultmedicine.medical_specialtyPathologyGlutensBiopsyImmunocytochemistryPancreatitis-Associated ProteinsBiologyGastroenterologyCoeliac diseaseJejunumIntestinal mucosaAntigens NeoplasmLectinsInternal medicineIntestine SmallBiomarkers TumormedicineAnimalsHumansLectins C-TypeIntestinal MucosaPancreatitis-Associated ProteinsChildGastroenterologyAcute-phase proteinInfantmedicine.diseaseImmunohistochemistrySmall intestineImmunoglobulin ACeliac DiseaseJejunummedicine.anatomical_structureChild PreschoolImmunoglobulin GPancreatitisFemaleRabbitsAcute-Phase Proteins
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La antropología como ciencia libidinosa. Diderot y el viaje de Bougainville

2005

Son innumerables los estudios que han abordado, desde temprano, la historia de la constitución de la antropología como disciplina empírica con vocación 'científica', como una de las ciencias humanas. Se muestra así una cierta obsesión por los orígenes, quizá síntoma de una frágil identidad. Uno de esos textos, de los más tempranos, The History of Anthropology} 1 fue escrito por Boas justo al principio del siglo pasado (1904) y tiene por objeto -fue una conferencia dada ante un publico académico variopintoreflexionar históricamente sobre una disciplina que todavía se debate para delimitar cuál es su objeto y método epistemológicos. Boas advierte desde el principio que no va a proceder dicien…

Antropología culturalEurocentrismoUniversalismoDiderot DenisCientificidadSexualidadBougainville Louis-AntoineAntropologiaMétodoMoralRelativismoOrigen
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Bouthors Jean-Louis-Alexandre

2007

Entrée de dictionnaire; Dictionnaire historique des juristes français XIIe-XXe siècles

Bouthors Jean-Louis-Alexandre[SHS.DROIT]Humanities and Social Sciences/Law[ SHS.HIST ] Humanities and Social Sciences/History[SHS.DROIT] Humanities and Social Sciences/Law[SHS.HIST] Humanities and Social Sciences/History[ SHS ] Humanities and Social Sciences[SHS] Humanities and Social Sciences[SHS.HIST]Humanities and Social Sciences/History[ SHS.DROIT ] Humanities and Social Sciences/Law[SHS]Humanities and Social Sciences
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Analysis of the Relationship Between Context and Solution Plan in Modelling Tasks Involving Estimations

2021

In this chapter we analyse students’ written solution plan of a sequence of modelling tasks involving estimations. Our research objective is to statistically analyse whether there is a relation between the solution plan and the characteristics of the context of the real estimation task. From previous work, we have identified some task variables that are directly related to the context. In this study we have designed a sequence of modelling tasks and we have analysed the productions of N = 224 Spanish pre-service primary school teachers. The results show that there is a relationship between the variables of the task and the solution plan used by the students in each case. From the results of…

EstimationSequenceRelation (database)Operations researchComputer scienceIs-aFlexibility (personality)Context (language use)Solution planTask (project management)
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HPLC-UV/Vis-APCI-MS/MS Determination of Major Carotenoids and Their Bioaccessibility from "Delica" (Cucurbita maxina) and "Violina" (Cucurbita moscha…

2018

Carotenoids are a widespread group of fat-soluble pigments, and their major nutritional importance comes from their pro-vitamin A activity and their antioxidant capacity. In this study, two different pumpkin cultivars (Cucurbita maxima, also named `Delica&rsquo

Luteincarotenoids pumpkins HPLC-UV/Vis-APCI-MS/MS C30 column bioaccessibilitymedicine.medical_treatmentPharmaceutical ScienceC30 columnArticleAnalytical ChemistryNOHPLC-UV/Vis-APCI-MS/MSMatrix (chemical analysis)lcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologyCucurbitalcsh:Organic chemistryTandem Mass SpectrometryDrug DiscoverymedicineFood scienceCookingPhysical and Theoretical ChemistryCarotenoidChromatography High Pressure Liquidpumpkinschemistry.chemical_classificationbiologyChemistryOrganic ChemistryCarotenecarotenoidsfood and beveragesC30-column04 agricultural and veterinary sciencesPigments Biologicalbiology.organism_classification040401 food sciencebioaccessibilityBioavailabilitySpectrometry FluorescenceChemistry (miscellaneous)Cucurbita moschataMolecular MedicineDigestionCucurbita maxima
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