Search results for "Isola"

Pulmonary embolism location is associated with the co-existence of the deep venous thrombosis.

2019

Multiple studies have shown that in approximately half of individuals with pulmonary embolism (PE), the deep venous thrombosis (DVT) is not evident at the moment of PE diagnosis. The underlying factors and the origin of PE in these patients are not completely understood: missed DVT, embolization of DVT in its entirety, or de-novo PE being possible explanations. The aim of this study was to evaluate the differences in PE patient with or without co-existing DVT. Sixty-three consecutive PE patients were included. Whole leg bilateral Doppler compression ultrasound was performed to all patients. The PE location and extension, C-reactive protein, platelet count, hemostatic markers FV, FVIII, FXII…

Disease-modifying drugs can reduce disability progression in relapsing multiple sclerosis

2020

Abstract An ever-expanding number of disease-modifying drugs for multiple sclerosis have become available in recent years, after demonstrating efficacy in clinical trials. In the real-world setting, however, disease-modifying drugs are prescribed in patient populations that differ from those included in pivotal studies, where extreme age patients are usually excluded or under-represented. In this multicentre, observational, retrospective Italian cohort study, we evaluated treatment exposure in three cohorts of patients with relapsing-remitting multiple sclerosis defined by age at onset: paediatric-onset (≤18 years), adult-onset (18–49 years) and late-onset multiple sclerosis (≥50 years). We…

Social, Occupational, and Cultural Adaptation During a 12-Month Wintering in Antarctica.

2016

Background and methods Life in isolated and confined environments (ICEs) is subject to important constraints which can generate psychosociologically impaired outcomes. This study investigated psychological, social, occupational, and cultural variables which are among the most important determinants in adaptation to a one-year wintering in Antarctica for 13 international subjects. Results Our findings confirm and give further insight into the role of social (Cohesiveness, Social Support) and occupational (Implementation/Preparedness, Counterproductive Activity, Decision Latitude, and Psychological Job Demands) dimensions of adaptation to ICEs. Relationships between various social and occupat…

For patients with breast cancer, geographic and social disparities are independent determinants of access to specialized surgeons. A eleven-year popu…

2012

Abstract Background It has been shown in several studies that survival in cancer patients who were operated on by a high-volume surgeon was better. Why then do all patients not benefit from treatment by these experienced surgeons? The aim of our work was to study the hypothesis that in breast cancer, geographical isolation and the socio-economic level have an impact on the likelihood of being treated by a specialized breast-cancer surgeon. Methods All cases of primary invasive breast cancer diagnosed in the Côte d’Or from 1998 to 2008 were included. Individual clinical data and distance to the nearest reference care centre were collected. The Townsend Index of each residence area was calcul…

OVERCOMING SOCIAL ISOLATION WITH DIGITAL TECHNOLOGIES AMONG AGEING POPULATIONS DURING COVID-19

2021

During Covid-19 social isolation has become more common worldwide, however, some groups, especially elderly people, might have experienced dramatically limited communication due to the lack of skills and access to digital technologies. In this paper, we examined if education was associated with the use of digital technologies to maintain contacts with a family, friends, other social networks and services. The survey was conducted in June-August 2020 by doing 1089 computer-assisted telephone interviews. The questions examined how people aged 50 years and older coped with socioeconomic and health-related impact of COVID-19.We used logistic regression analysis to study the association between …

Aggressiveness, social isolation and adjustment: The role of social reputation.

2010

The complexity of loneliness.

2018

Loneliness is a prevalent and global problem for adult populations, and a number of different studies have linked it to multiple chronic conditions, including: heart disease, lung disease, cardiovascular disease, hypertension, atherosclerosis, stroke, and metabolic disorders, such as obesity and metabolic disease. Is a major predictor of psychological problems, such as depression, psychological stress, and anxiety. Loneliness is linked to overall morbidity and mortality in adult populations. But limited interventions have demonstrated long-term effectiveness in reducing loneliness in adults with these same chronic conditions. Our research of the extant literature addresses the following que…

Cohomologie relative des applications polynomiales

2001

Let F be a polynomial dominating mapping from Cn to Cq with n>q. We study the de Rham cohomology of the fibres of F, and its relative cohomology groups. Let us fix a strictly positive weighted homogeneous degree on C[x1,…,xn]. With the leading terms of the coordinate functions of F, we construct a fibre of F that is said to be “at infinity”. We introduce the cohomology groups of F at infinity. These groups, denoted by Hk(F−1(∞)), enable us to study all the other cohomology groups of F. For instance, if the fibre at infinity has an isolated singularity at the origin, we prove that any quasi-homogeneous basis of Hn−q(F−1(∞)) provides a basis of all groups Hn−q(F−1(y)), as well as a basis of t…

N-Terminal amino acid sequence analysis indicates that isolated atrial amyloid is derived from atrial natriuretic peptide

1988

Isolated atrial amyloid, the most frequent senile cardiac amyloid type, was chemically analysed. Amyloid fibrils obtained from a patient (NIP) were extracted and the predominant low-molecular-weight polypeptide (approximately 3.5 kDa, designated ASc2 NIP) was isolated by size exclusion high performance liquid chromatography in 60% formic acid. N-Terminal amino acid sequence analysis of this polypeptide was identical to that of the atrial natriuretic peptide alpha-hANP for the first 12 residues determined.

H2-Antihistaminika, 36. Mitt. Isolamtidin und Analoge

1987

Isolamtidin (9a), ein Stellungsisomer des Lamtidins (8a), sowie die analogen N3-substituierten 1-Methyl-1H-1,2,4-triazol-3,5-diamine 9e-i, k wurden durch spezifische Synthese dargestellt und am isolierten Meerschweinchenvorhof und an der histaminstimulierten Sauresekretion der narkotisierten Ratte auf H2-antagonistische Wirkung untersucht. H2-Antihistaminics, XXXVI: Isolamitidine and Analogues Isolamitidine (9a), a position isomer of lamtidine (8a), as well as the analogous N3-substituted 1-methyl-1H-1,2,4-triazole-3,5-diamines 9e-i, k were prepared and tested for H2-antagonistic activity on the isolated guinea-pig atrium and towards the histamine-stimulated acid secretion of the anaestheti…