Search results for "Isovitexin"

showing 3 items of 3 documents

Flavonoids from Acacia pennata and their Cyclooxygenase (COX-1 and COX-2) Inhibitory Activities

2007

Two new flavonoids quercetin 4'-O-alpha-L-rhamnopyranosyl-3-O-beta-D-allopyranoside (1) and apigenin 6-C-[2''-O-(E)-feruloyl- beta-D-glucopyranosyl]-8-C-beta-glucopyranoside (2), along with the known isorhamnetin 3-O-alpha-L-rhamnopyranoside (3), kaempferol 3-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranoside (4), and isovitexin (5) were isolated from the leaves of Acacia pennata Willd. (Mimosaceae) and tested for their anti-inflammatory activity. Their structures were determined by 1D and 2D NMR and mass spectrometry. They were tested for an inhibitory effect on COX-1 and COX-2, showing 60-90% inhibition at 10(-4) g/mL and 5-14% inhibition at 10(-4) g/mL, respectively.

FlavonoidIsovitexinPharmaceutical ScienceBiologyPharmacognosyAnalytical ChemistryInhibitory Concentration 50chemistry.chemical_compoundDrug DiscoveryHumansCyclooxygenase InhibitorsPhenolsIsorhamnetinPharmacologychemistry.chemical_classificationTraditional medicinePlant ExtractsOrganic ChemistryAcaciaFlavonesPlant LeavesComplementary and alternative medicinechemistryBiochemistryCyclooxygenase 2ApigeninCyclooxygenase 1Molecular MedicineKaempferolQuercetinPhytotherapyPlanta Medica
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On the Occurrence of Flavonoids in the acrocarpous Mosses

1978

Summary By means of paper chromatography two flavonoids were isolated from the methanolic extract of the moss Mnium undulatum. One substance was identified by chromatographic data, absorption spectra and acid hydrolysis as isovitexin-7-0-glucoside (saponarin). The second substance resists acid hydrolysis and is by chromatography and absorption spectrum identical with apigenin-6,8-di-C-glycoside (viccnin).

chemistry.chemical_compoundPaper chromatographyChromatographyAbsorption spectroscopychemistrySaponarinIsovitexinAcid hydrolysisGeneral MedicineZeitschrift für Pflanzenphysiologie
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Anti-inflammatory activity of flavonoids from Cayaponia tayuya roots.

2008

Taiuiá or tayuya (Cayaponia tayuya, Cucurbitaceae) is a climbing, lignified plant with a large swollen root that has traditionally been used as an anti-inflammatory and anti-rheumatic agent in the folk medicine of Brazil, Peru, and Colombia.We have assayed the pharmacological properties of a flavonoid fraction obtained from the butanol extract of Cayaponia tayuya roots using two models of topical mouse ear oedema, paying special attention to its influence on the induction on pro-inflammatory enzymes and peptidic mediators.The in vivo experiments involved both the acute oedema induced by a single application of TPA and the subchronic inflammation brought on by repeated applications of TPA. T…

medicine.drug_classFlavonoidIsovitexinAnti-Inflammatory AgentsNitric Oxide Synthase Type IIPharmacologyPharmacognosyColombiaPlant RootsAnti-inflammatoryCell Linechemistry.chemical_compoundMiceWestern blotIn vivoDrug DiscoveryPerumedicineAnimalsPharmacologychemistry.chemical_classificationFlavonoidsInflammationbiologymedicine.diagnostic_testbusiness.industryPlant ExtractsMacrophagesbiology.organism_classificationCayaponia tayuyaCucurbitaceaeDisease Models AnimalchemistryBiochemistryCyclooxygenase 2biology.proteinFemaleCyclooxygenaseMedicine TraditionalbusinessBrazilJournal of ethnopharmacology
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