Search results for "JAK"
showing 10 items of 708 documents
Wykorzystanie ram jakości M.J. Epplera do ewaluacji jakości informacji serwisów internetowych PWSZ
2019
The article presents the evaluation of information quality on the websites of the State Higher Vocational Schools (PWSZ) in Poland. The information quality framework proposed by M.J. Eppler was adopted as a diagnostic tool to identify gaps in information quality. The assessment was conducted from the user's perspective. Firstly, the ranking of the PWSZ sites in Poland was created. Secondly, the criteria for the quality of information in the website infrastructure were analysed. The conclusions result in a statement that most websites demonstrate a low level of information quality. The scope of synthetic measures ranges from 60.0% to 90.8% which indicates a wide variation in the information …
Thrombin generation - a potentially useful biomarker of thrombotic risk in Philadelphia-negative myeloproliferative neoplasms.
2017
The diagnosis of essential thrombocythemia and polycythemia vera is often made during a thrombotic event which can be serious. Philadelphia-negative chronic myeloproliferative neoplasia patients have an increased thrombotic risk. This is assessed using various scoring systems but these are far from ideal and individual risk. The currend trend to personalised medicine requires finding the most useful thrombotic risk biomarker in these patients. Routine tests for coagulation do not take account of both pro- and anti-coagulant factors which is why these tests are not useful in patients with Philadelphia-negative myeloproliferative neoplasms. Thrombin generation reflects more accurately the bal…
Pertuzumab monotherapy after trastuzumab-based treatment and subsequent reintroduction of trastuzumab: activity and tolerability in patients with adv…
2012
Purpose The combination of pertuzumab and trastuzumab resulted in a clinical benefit rate (CBR) of 50% in patients with human epidermal growth factor receptor 2 (HER2) –positive breast cancer whose disease progressed during prior trastuzumab-based therapy. To define whether this previously observed encouraging activity was a result of the combination of pertuzumab and trastuzumab or of pertuzumab alone, we recruited a third cohort of patients who received pertuzumab without trastuzumab. We then investigated the impact of reintroducing trastuzumab to patients whose disease progressed on pertuzumab monotherapy. Patients and Methods Twenty-nine patients with HER2-positive breast cancer whose d…
Targeted next generation sequencing of breast implant-associated anaplastic large cell lymphoma reveals mutations in JAK/STAT signalling pathway gene…
2016
Kreatywność jako czynnik rozwoju obszarów wiejskich na przykładzie województwa opolskiego
2018
W opracowaniu przedstawiono znaczenie i wpływ kreatywności oraz innowacyjności na rozwój obszarów wiejskich. Zdefiniowano pojęcie kreatywności i sektorów kreatywnych, wskazano działania w zakresie rozwoju kreatywności i aktywizacji mieszkańców obszarów wiejskich. Określono wpływ działalności pozarolniczej na jakość życia ludności wiejskiej oraz przedstawiono przykłady aktywizacji i różnych działań kreatywnych będących formą przedsięwzięć innowacyjnych na obszarach wiejskich województwa opolskiego.
Brief an Garlieb H. Merkel
1799
Ms. 930a, Nr. 8, Bl. 22r-23v Böttiger, Karl August. Brief an Garlieb H. Merkel, Weimar, d[en] 13. November 1797 Autora rokraksts / Autograph, vācu, angļu un latīņu val. / Deutsch, Englisch und Latein [4] lpp. / S. Attēlu numuri / Bildnummern: 930a-008-1 – 930a-008-4 Der Verfasser nennt in diesem inhaltsreichen Brief zahlreiche Namen und hält nicht nur die Verbindung mit Merkel, die aus dessen erstem Aufenthalt in Weimar resultierte, aufrecht, sondern gibt ihm weitere Hinweise und Empfehlung für seinen weiteren Aufenthalt in Dänemark. So rät er zur Übersetzung dreier Romane aus dem Englischen, darunter Jane Wests „A gossip's story“ (London 1796). Ferner bittet der Verfasser Merkel um Gefälli…
Kemin seutu
1595
Erinomaiset matematiikan osaajat
2018
Predicting consumer purchase intention toward hybrid vehicles : testing the moderating role of price sensitivity
2020
PurposeToday, global warming is one of the most acute challenges in the world, prominently caused by greenhouse gases. The introduction of hybrid-vehicles (HVs) is thus, one of the industrial initiatives to tackle this challenge by allowing at least some proportionate reduction in global-gas-emissions. Such initiatives like HVs have also affected the consumers’ green-purchase-intention (GPI). Hence, underpinned into the theory of planned behaviour (TPB), this study aims to analyze consumers’ response in terms of GPI for HVs, in addition to exploring the moderating-effect of price-sensitivity between independent-variables (attitude, subjective norms and perceived behavioural control) and con…
Der pikareske Roman als Katalysator in geschichtlichen Abläufen : erzählerische Kommunikationsmodelle in Das Leben des Lazarillo von Tormes, bei Thom…
2005
Anna-Riitta Tunturi tutki väitöskirjassaan pikareski- eli veijariromaanin eri ilmenemismuotoja historiallisena läpileikkauksena, sosiologisena ilmiönä ja romaanitaiteen osa-alueena. Sana ”pícaro” tulee kastiliankielen verbistä ”picar”, joka tarkoittaa alempiarvoisten ammattien harjoittamista, kuten picador de toros, pikadori härkätaistelussa, toreadorin avustaja. Saksaksi sana on Schelm, joten oma sanamme kelmi on saksalaista lainaa. Lisäksi suomen kielessä on veijari, huijari, heittiö tai hulttio, ja lisääkin varmasti löytyy. This dissertation in comparative literature examines several Finnish picaresque novels of 20th century in relation to some classical continental European novels such …