Search results for "JUNCTION"
showing 10 items of 862 documents
Carbon nanotube derivatives for electro-optical active bulk heterojunctions
2012
Co-culture of rat brain cells as a tool for studying cell-cell interactions
2012
Brain capillary endothelial cells (BCECs) form the blood-brain barrier (BBB) in response to interaction with other brain cells (astrocytes, pericytes and neurons). BCECs are characterized by tight junctions (TJ), maturation and stabilization of which require different proteins, such as occludin. When co-cultured with astrocytes and neurons, BCECs were found to form a monolayer resembling the natural BBB: paracellular flux of dopamine and sucrose (i.e. compounds which are unable to cross the BBB in vivo) significantly decreased (1), while the transendothelial electrical resistance (TEER) increased. In these conditions, BCECs produced a larger amount of occludin and tended to localize it at t…
Variants of human CLDN9 cause mild to profound hearing loss
2021
Hereditary deafness is clinically and genetically heterogeneous. We investigated deafness segregating as a recessive trait in two families. Audiological examinations revealed an asymmetric mild to profound hearing loss with childhood or adolescent onset. Exome sequencing of probands identified a homozygous c.475G>A;p.(Glu159Lys) variant of CLDN9 (NM_020982.4) in one family and a homozygous c.370_372dupATC;p.(Ile124dup) CLDN9 variant in an affected individual of a second family. Claudin 9 (CLDN9) is an integral membrane protein and constituent of epithelial bicellular tight junctions that form semi-permeable, paracellular barriers between inner ear perilymphatic and endolymphatic compartment…
Le renouvellement du contrôle juridictionnel de l’administration au moyen du recours pour excès de pouvoir
2017
The role of the administrative judge (the excess of power) has evolved due to the implementation of the various texts adopted recently as well as the developments in the case-law in recent years. In many areas, its role now goes beyond the mere confrontation of an administrative act with the rule of law. At the heart of the annulment decision is a statement and an assessment of the facts, apart from the interpretation of the law, which were usually separated by the principle of separation between the administration and its judge.Some jurisprudence which has become very classical, as well as others more recent, can be considered as characteristic manifestations of this new tendency of the ju…
Conjunctions and syntactic complexity: Development of the use of conjunctions in written learner Finnish
2022
Kielitaidon kehittymistä voidaan tutkia mittaamalla oppijankielen sujuvuutta, tarkkuutta ja kompleksisuutta. Kompleksisuus voidaan määritellä oppijankielen monipuolisuudeksi ja kehittyneisyydeksi, mutta syntaktista kompleksisuutta on kansainvälisessä toisen kielen oppimisen tutkimuksessa tyypillisesti mitattu alisteisiin lauserakenteisiin perustuvilla kvantitatiivisilla mittareilla. Tässä artikkelissa syntaktisen kompleksisuuden kehitystä tutkitaan tarkastelemalla rinnastus- ja alistuskonjunktioiden käyttöä suomi toisena kielenä -teksteissä Eurooppalaisen viitekehyksen eri taitotasoilla. Aineistona käytetään Jyväskylän yliopiston Cefling-hankkeen oppijansuomen korpuksen tekstejä. Rinnasteis…
Development of an inductive NIS thermometer
2012
Normal metal-Insulator-Superconductor (NIS) tunnel junction thermometers have been under heavy research since 1976 after Rowell and Tsui first presented thanks to their excellent sensitivity to the temperature change in millikelvin regime. In this work, we have designed and studied an inductive readout for NIS tunnel junctions by using on-chip planar inductors and a DC SQUID (Superconducting Quantum Interference Device) to develop a sensitive and fast thermometer for studies of nanoscale heat conduction and bolometry. In this thesis, the processing of the samples fabricated in Nanoscience Center in Jyväskylä are presented, and several processing challenges have been dealt with and the fabri…