Search results for "KAc"
showing 10 items of 281 documents
Wykorzystanie środków unijnych a realizacja założeń nowego modelu wspomagania szkół i nauczycieli na przykładzie Ośrodka Doskonalenia Nauczycieli w K…
2017
Doskonalenie nauczycieli to jeden z kluczowych czynników poprawy jakości edukacji często poddawany ewaluacji. W artykule dokonano charakterystyki wybranych projektów realizowanych z funduszy Unii Europejskiej przez Ośrodek Doskonalenia Nauczycieli w Kaliszu oraz wskazano procesy związane z ich wdrażaniem. Celem badania była ocena zmodernizowanego systemu doskonalenia nauczycieli i próba określenia, jak model ten sprawdza się w rzeczywistości. Przeprowadzona analiza pozwoliła wskazać efekty szkoleń oraz mankamenty dotyczące struktury i funkcjonowania opisywanego systemu. W artykule zamieszczone zostały wyniki badań, wnioski i rekomendacje.
Kształcenie podyplomowe pielęgniarek i położnych na podstawie zadań Okręgowej Izby Pielęgniarek i Położnych w Katowicach w latach 2000-2017
2019
Obowiązek stałej aktualizacji wiedzy pielęgniarek i położnych reguluje ustawa o zawodzie pielęgniarki i położnej oraz kodeks etyki. Okręgowa Izba Pielęgniarek i Położnych w Katowicach, jako organizator kształcenia podyplomowego, prowadząc wszystkie rodzaje kształcenia, przeszkoliła dotąd ponad 50 tysięcy uprawnionych osób. Celem pracy było dokonanie ewaluacji podjętych działań, w oparciu o materiały korporacyjne z lat 2000-2017. Przedstawione wyniki, w ujęciu ilościowym, obrazują poziom realnego zainteresowania kursami specjalistycznymi oraz kwalifikacyjnymi, a także źródła ich finansowania.
Prevalence of Hearing Impairment Among High-Risk Newborns in Ibadan, Nigeria
2018
The burden of severe hearing impairment is increasing with two-thirds of these hearing impaired people residing in developing countries. Newborn hearing screening helps to identify early, babies who need intervention in order to prevent future disability. Neither universal nor targeted hearing screening programme is available in Nigeria. Objectives: This study was carried out to assess the prevalence of hearing impairment among high-risk newborns in UCH and the associated risk factors. Materials and Methods: Two hundred one newborns in the neonatal unit of UCH with risk factors for hearing impairment had hearing screening done using automated auditory brainstem response (AABR) at 30, 45, an…
A comparative study of the population pharmacokinetics of gentamicin and amikacin in newborn patients
1993
SUMMARY The population kinetics of gentamicin and amikacin were studied comparatively in newborn patients with a similar range of gestation age (37.9 ± 2.9 and 36.7 ± 3.6 weeks), postnatal age (13.8 ± 7.4 and 16.7 ± 7 days) and weight (2.85 ± 0.57 and 2.72 ± 0.75 kg), undergoing routine therapeutic monitoring of their serum levels. Individual kinetic analysis of serum drug levels was done using a single-compartment model. The population model employed assumes the existence of residual variability in the serum concentrations and interindividual variability in the pharmacokinetic parameters. The clearance and the apparent distribution volume were calculated for each patient using a two-stage …
Efecto de la administración concomitante de indometacina o ibuprofeno en la farmacocinética de amikacina en neonatos prematuros
2006
Objective: To evaluate whether the concomitant administration of ibuprofen or indomethacin plus amikacin may alter the latter drug's pharmacokinetic parameters, and hence amikacin plasma levels. Method: Retrospective cohort study performed by reviewing the medical records of premature children with persistent ductus arteriosus receiving amikacin and ibuprofen, or amikacin and indomethacin. They were divided up into three groups: group 1: treatment with amikacin went before indomethacin or ibuprofen; group 2: simultaneously treated with amikacin and indomethacin; group 3: simultaneously treated with amikacin and ibuprofen. Pharmacokinetic parameters, distribution volume, and amikacin clearan…
Effects of the prolonged thoracic epidural analgesia on ventilation function and complication rate after the lung cancer surgery.
2006
Thoracic epidural analgesia has been considered to have a good anesthetic efficacy and to decrease the postoperative complication rate, while its effect upon the ventilation function is still the topic of many clinical studies. The aim of this study was to evaluate the course of early postoperative period using thoracic epidural analgesia. Material and methods. A total of 453 patients undergoing the operation due to the non–small cell carcinoma were selected and examined. Their postoperative complications and mortality rate were evaluated. In 79 patients, arterial oxygen saturation (SaO2), forced vital capacity, forced expiratory volume in the first second, and the efficacy of analgesia wer…
Fit-for-purpose chromatographic method for the determination of amikacin in human plasma for the dosage control of patients
2015
In this paper, a simple, rapid and sensitive method based on liquid chromatography with fluorimetric detection (HPLC-FLD) for the determination of amikacin (AMK) in human plasma is developed. Determination is performed by pre-column derivatization of AMK with ortho-phtalaldehyde (OPA) in presence of N-acetyl-L-cysteine (NAC) at pH 9.5 for 5 min at 80 °C. In our knowledge, this is the first time that NAC has been used in AMK derivatization. Derivatization conditions (pH, AMK/OPA/NAC molar ratios, temperature and reaction time) are optimized to obtain a single and stable, at room temperature, derivative. Separation of the derivative is achieved on a reversed phase LC column (Kromasil C18, 5 μ…
Estetica e resistenza. Lukács interprete di Goethe
2013
Lukacs, Goethe
Antibiotic Susceptibility Patterns and Molecular Epidemiology of Metallo-β-Lactamase Producing Pseudomonas Aeruginosa Strains Isolated From Burn Pati…
2014
BACKGROUND: Failure in the treatment of burn patients infected with Pseudomonas aeruginosa could happen as a result of the acquisition of antibiotic resistance, including carbapenems. OBJECTIVES: The aim of the present study was to investigate the phenotypic and genotypic characteristics of the Pseudomonas aeruginosa strains, isolated from burn patients. PATIENTS AND METHODS: During a 12 month period, in this cross-sectional study, two hundred seventy strains of Pseudomonas aeruginosa were isolated from the burn patients in Ghotbeddin Burn Hospital, Shiraz, Iran. Screening for the carbapenem resistance in the isolates was carried out by the E test method. Sensitivity patterns of metallo-β-l…
Brownian motion in trapping enclosures: Steep potential wells, bistable wells and false bistability of induced Feynman-Kac (well) potentials
2019
We investigate signatures of convergence for a sequence of diffusion processes on a line, in conservative force fields stemming from superharmonic potentials $U(x)\sim x^m$, $m=2n \geq 2$. This is paralleled by a transformation of each $m$-th diffusion generator $L = D\Delta + b(x)\nabla $, and likewise the related Fokker-Planck operator $L^*= D\Delta - \nabla [b(x)\, \cdot]$, into the affiliated Schr\"{o}dinger one $\hat{H}= - D\Delta + {\cal{V}}(x)$. Upon a proper adjustment of operator domains, the dynamics is set by semigroups $\exp(tL)$, $\exp(tL_*)$ and $\exp(-t\hat{H})$, with $t \geq 0$. The Feynman-Kac integral kernel of $\exp(-t\hat{H})$ is the major building block of the relaxatio…