Search results for "KDE"
showing 10 items of 10 documents
A Model for ERD2 Function in Higher Plants
2020
ER lumenal proteins have a K(H)DEL motif at their C-terminus. This is recognized by the ERD2 receptor (KDEL receptor in animals), which localizes to the Golgi apparatus and serves to capture escaped ER lumenal proteins. ERD2-ligand complexes are then transported back to the ER via COPI coated vesicles. The neutral pH of the ER causes the ligands to dissociate with the receptor being returned to the Golgi. According to this generally accepted scenario, ERD2 cycles between the ER and the Golgi, although it has been found to have a predominant Golgi localization. In this short article, we present a model for the functioning of ERD2 receptors in higher plants that explains why it is difficult t…
Breakup and default risks in the great lockdown
2023
Abstract In this paper, we exploit CDS quotes for contracts denominated in different currencies and with different default clauses to estimate the risk of a breakup of the Eurozone and the propagation of breakup and default risks after the COVID-19 shock. Our main result is that the risk of a Eurozone breakup is significant although, quantitatively, it is not larger than in the period before the COVID-19 shock. In addition, we find that an increase in the redenomination risk in one country is associated with an increase in default premia and bond spreads in other Eurozone countries. Finally, we find that a sizeable fraction of the changes in the cost of insuring against redenomination and d…
Latvijas Vēstures Institūta Žurnāls. 2016, Nr. 1 (98)
2016
Valsts kultūrkapitāla fonds
Activation of the Proapoptotic Unfolded Protein Response in Plaques of the Human Carotid Artery
2014
Objective To analyze expression of keystone markers of apoptosis and the proapoptotic signaling pathway “unfolded protein response” (UPR) in rupture-prone plaques of the human carotid artery. Methods Plaque specimens were obtained during endarterectomy for high-grade carotid stenosis, and were formalin-fixed. Ten specimens were identified that exhibited criteria of advanced rupture-prone atherosclerotic plaques, and histological and immunohistological analysis of markers of apoptosis (cleaved Caspase-3, TUNEL) and UPR (KDEL, ATF3, CHOP, CHAC-1) was performed. In addition, co-localization of apoptosis and UPR-activation was assessed by double-immunohistochemistry. Results The mean size of th…
IT palīdzības dienestos pielietoto tehnoloģiju izpēte
2020
Bakalaura darbs sniedz ieskatu, kas ir palīdzības dienests un kāda ir tā loma. Tika apskatītas 6 dažādas (Jira Service Desk, Freshdesk, Zendesk, JitBit, Talkdesk, CloudTalk) pieteikumu reģistrācijas un zvanu platformas, ko izmanto palīdzības dienestos. Bakalaura sākuma daļā tika veikts īss ieskats, kas ir palīdzības dienests. Tika veikts platformu funkciju apraksts salīdzinātas to sniegtās iespējas. Pētījuma daļā tika aprakstītas platformas, ko izmanto kādā reālā palīdzības dienestā, veikts izpildījuma novērtējums un izdarīti secinājumi, vai nomainot izmantotās platformas uz jaunākajām uzlabotos palīdzības dienesta darbība. Bakalaura darba mērķis ir izpētīt kādas tehnoloģijas tiek izmantota…
Compte rendu de "Charles Brockden Brown. La part du doute" de Marc Amfreville. Transatlantica [online], (1 | 2003), URL : http://transatlantica.revue…
2003
Computational Techniques for the Analysis of Small Signals in High-Statistics Neutrino Oscillation Experiments
2020
The current and upcoming generation of Very Large Volume Neutrino Telescopes – collecting unprecedented quantities of neutrino events – can be used to explore subtle effects in oscillation physics, such as (but not restricted to) the neutrino mass ordering. The sensitivity of an experiment to these effects can be estimated from Monte Carlo simulations. With the high number of events that will be collected, there is a trade-off between the computational expense of running such simulations and the inherent statistical uncertainty in the determined values. In such a scenario, it becomes impractical to produce and use adequately-sized sets of simulated events with traditional methods, such as M…
Attityder till finska språket och språklig identitet på Åland : en analys av åländska tidningar
2015
Tämän kvalitatiivisen tutkimuksen tarkoituksena on selvittää ahvenanmaalaisten kieliasenteita suomen kieltä kohtaan sekä millainen on yleinen käsitys ahvenmaalaisten kielellisestä identiteetistä kahdessa suurimmassa ahvenanmaalaisessa paikallislehdessä. Materiaali koostuu 64 erilaisesta mielipide- ja pääkirjoitusartikkelista, jotka on julkaistu 1.1.2007 – 31.12.2012 Nya Åland ja Ålandstidningen -lehdissä. Tutkimusmetodina käytettiin sisällönanalyysia ja diskurssianalyysiä. Kieliasenteita analysoitiin pääosin sisällönanalyysin avulla ja löydetyt argumentit luokiteltiin kommuni-katiivisiin, omakohtaisiin, kansallisiin ja oikeudellisiin argumentteihin. Tulosten mukaan asenteet ovat erilaisia e…
A2Ba: Adaptive Background Modelling for Visual Aerial Surveillance Conditions
2015
International audience; Background modelling algorithms are widely used to define a part of an image that most time remains stationary in a video. In surveillance tasks, this model helps to recognize those outlier objects in an area under monitoring. Set up a background model on mobile platforms (UAVs, intelligent cars, etc.) is a challenging task due camera motion when images are acquired. In this paper, we propose A2Ba, a robust method to support instabilities caused by aerial images fusing different information about image motion. We used frame difference as first approximation, then age of pixels is estimated. This latter gives us an invariability level of a pixel over time. Gradient di…
Riskien havainnollistamisohjelmisto RiskDemo
2018
RiskDemo on vapaasti käytettävä ohjelmistotyökalu, joka on tarkoitettu havainnollistamaan riskejä todennäköisyyslaskennan ja tilastotieteen näkökulmasta. Ohjelmalla voidaan havainnollistaa riskejä monenlaisten graafisten esitysten, taulukoiden ja riskilukujen avulla. Tällä hetkellä sillä voidaan havainnollistaa demografiaa, korko- ja osakesijoittamista sekä klassista vararikkoteoriaa. Tässä artikkelissa esitellään RiskDemo-ohjelmiston ominaisuudet ja opastetaan sen käyttämiseen riskien havainnollistamisessa. Lukija voi RiskDemon avulla tutustua moniin riskienhallinnan avainkäsitteisiin havainnollisessa ja konkreettisessa muodossa. peerReviewed