Search results for "KER"

Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia

2017

Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…

Predictive value of p53, Ki67 and TLR5 in neoplastic progression of Barrett’s esophagus: a matched case–control study

2022

Abstract Barrett’s esophagus progresses to high-grade dysplasia or cancer along the well-established metaplasia-dysplasia-adenocarcinoma sequence. The aim of this study was to evaluate the value of p53, Ki67, and toll-like receptor 5 (TLR5) in prediction of malignant progression of Barrett’s metaplasia and low-grade dysplasia. This was a retrospective matched case–control study based on Northern and Central Finland population. Patients diagnosed with esophageal high-grade dysplasia or adenocarcinoma were included. From these patients, all previous endoscopy samples were obtained along with original diagnostic HE-slides and clinical data. Age- and sex-matched patients with non-progressing Ba…

Association between socioeconomic factors and origin of hospital referrals among patients with oral cancer.

2022

The Brazilian Unified Health System (SUS) is responsible for offering free assistance to more than 100 million Brazilians, including treatment of oral cancer lesions. Considering that the Brazilian public system aids the most vulnerable population, this study analyzed whether the origin of hospital referrals of patients with oral cancer is associated with socioeconomic factors. A cross-sectional study was carried out from cancer hospital records of the National Cancer Institute (RHC-INCA), considering the primary locations (C00 to C06) diagnosed between 2016 and 2019. Data on gender, skin color (white and non-white), education (no schooling, incomplete or complete elementary education; high…

Cross‐sectional associations between physical fitness and biomarkers of inflammation in children : the PANIC study

2023

Background Systemic low-grade inflammation has been proposed as an underlying pathophysiological mechanism for cardiometabolic diseases. We investigated the associations of physical fitness with systemic low-grade inflammatory state in a population sample of children. Methods Altogether 391 children aged 6–9 years were examined. Cardiorespiratory fitness (maximal power output, Wmax) was assessed by a maximal cycle ergometer test and neuromuscular fitness by hand grip strength, sit-up, standing long jump, 50-metre shuttle run, static balance, sit-and-reach, and box and block tests. Body fat percentage (BF%) and lean mass (LM) were assessed by dual-energy X-ray absorptiometry. High sensitivit…

Rural shopkeepers in a time of crisis

2021

Inkerinsuomalaisten paluumuuttajien elämää Jyväskylässä

1997

The Effect of Smartphone-Based Cognitive Training on the Functional/Cognitive Markers of Schizophrenia: A One-Year Randomized Study

2020

Background: Cognitive impairment is associated with long-term disability that results in the deterioration of both the social and professional status of individuals with schizophrenia. The impact of antipsychotic therapy on cognitive function is insufficient. Cognitive training is therefore proposed as a tool for cognitive rehabilitation in schizophrenia. In this study we investigated the effect of self-administered cognitive training using a smartphone-based application on the cognitive function of paranoid schizophrenia patients focusing on response time, correct answer rate, incorrect answer rate, and fatigability to check, if these functions can be functional markers of successful cogni…

MILKER’S NODULE. A PERPLEXING FARMYARD INFECTION AND THREAT TO THE IMMUNOCOMPROMISED

2017

Milker’s nodules, also called paravaccinia, is a DNA virus transmitted from infected cows to humans. It results from contact with cattle, cattle byproducts, or fomites. Classified as an occupational disorder, those at risk of exposure include farmers, butchers, and agricultural tourists. The viral infection begins 5—15 days after inoculation as an erythematous-purple, round nodule with a clear depressed center, and a surrounding erythematous ring. While familiar to those in farming communities, the presence of the nodule may be concerning to others, particularly the immunosuppressed. Milker’s nodules are selflimited in immunocompetent individuals and heal without scarring within 8 weeks. An…

Gravity-derived Moho map for Latvia

2020

A precise understanding of crustal structure is essential to the fields of geodynamics, seismology and certain branches of geophysics. A boundary between the crust and the mantle is known as the MohoroviÄiÄ discontinuity, simply referred to as the âMohoâ. Moho geometry and depth have been extensively studied in Europe, but there are still regions with little information about it. One such area is the northern Baltics, Latvia in particular. So far, only one seismic refraction profile, spanning from Sovetsk (Kaliningrad) to Kohtla-Järve (Estonia), has been used to study the deep structure of the Earth in Latvia. We propose gravity inversion (ParkerâOldenburg algorithm) to gain more insight i…

Parlamentarismin kannattajasta vallankumouksen äänitorveksi : Suomen Sosialidemokraattisen Puolueen lehdistö 1917-1918

2018

The research topic of this dissertation is the press of the Social Democratic Party of Finland (SDP) from the March revolution of 1917 in Russia to the end of the Finnish Civil War in the spring of 1918. Under research are 16 party papers, which, however, were not owned by the party, and therefore neither under its guidance nor control. The papers' owners, local working class organizations, elected the editors-in-chief, who often held central posts in the party. In this way they could use their relatively independent positions to further their political views in their editorials. In the dissertation the press reports are bound with the ideology and policies of the SDP. The first theme is th…