Search results for "KHO"

3D numerical modeling of an anthropogenic sinkhole in the Marsala area of western Sicily

2013

“Почувствовать характер народа...” : (Эпизод из переписки Т. Л. Сухотиной-Толстой и Карлиса Эгле)

2016

Burkholderia cepacia septicemia in a patient with acute myeloid leukemia in postchemotherapy bone marrow aplasia

2013

The patients with hematologic malignancies are predisposed to develop infections with unusual bacteria, like Burkholderia cepacia, which is frequently resistant to many antibiotics and antiseptics. We present the case of a female patient with acute myeloid leukemia type 2 on the background of myelodysplastic syndrome, from whom Burkholderia cepacia was isolated in blood culture, after the 2(nd) cycle of induction. She was sensitive to ceftazidime, but its eradication was not easy. Five other patients were contaminated with this bacteria, but all of them had favourable evolution. The case is discussed in the context of those similar in literature.

Applications of the Connection between Approximation Theory and Algebra

2009

The aim of this paper is to illustrate a possibility of obtaining various theoretical results using the connection between multivariate interpolation and reduction process with respect to a H-basis of an ideal. Using this connection we can switch between interpolation theory and the theory of ideals. As a application of this connection, we found and proved an interesting identity, which is satisfied for all polynomials in d variables from an interpolation polynomial subspace.

Properties of Generalized Polynomial Spaces in Three Variables

2009

Multivariate interpolation is a topic which often appears in practical modeling problems. Different type of spaces of functions are used for solving interpolation problems. When the interpolation conditions are of different kind, by example, spacial and temporal, one possibility for modeling the problem is to use a generalize degree, in which the monomials exponents are weighted with a weight vector with integer components. In order to use such a generalize polynomial space as interpolation space, it is necessary to know the dimension and a basis of it. The aim of this article is to study and prove many properties of the generalize polynomial spaces in three variables.

Geometry of Quadrangles in Almqvist’s The Queen’s Tiara

2018

Quadrangles are repeatedly used in construction of scenes in Swedish author C. J. L. Almqvist’s novel The Queen’s Tiara. They limit and frame views. Repeating these structures creates connections between scenes. They form in relations between characters. Several quadrangular structures form around one main character called Tintomara, when she involuntarily attracts characters that fall in love in her. Also, quadrangles inside and beside each other are visible in scenes. Almqvist presented these forms in the elementary geometry textbook he published a year before this novel. peerReviewed

Diversity and Evolution of the Phenazine Biosynthesis Pathway

2010

ABSTRACT Phenazines are versatile secondary metabolites of bacterial origin that function in biological control of plant pathogens and contribute to the ecological fitness and pathogenicity of the producing strains. In this study, we employed a collection of 94 strains having various geographic, environmental, and clinical origins to study the distribution and evolution of phenazine genes in members of the genera Pseudomonas , Burkholderia , Pectobacterium , Brevibacterium , and Streptomyces . Our results confirmed the diversity of phenazine producers and revealed that most of them appear to be soil-dwelling and/or plant-associated species. Genome analyses and comparisons of phylogenies inf…

Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts

2021

Abstract Sinapigladioside is a rare isothiocyanate‐bearing natural product from beetle‐associated bacteria (Burkholderia gladioli) that might protect beetle offspring against entomopathogenic fungi. The biosynthetic origin of sinapigladioside has been elusive, and little is known about bacterial isothiocyanate biosynthesis in general. On the basis of stable‐isotope labeling, bioinformatics, and mutagenesis, we identified the sinapigladioside biosynthesis gene cluster in the symbiont and found that an isonitrile synthase plays a key role in the biosynthetic pathway. Genome mining and network analyses indicate that related gene clusters are distributed across various bacterial phyla including…

Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination

2020

Abstract Genome mining of one of the protective symbionts (Burkholderia gladioli) of the invasive beetle Lagria villosa revealed a cryptic gene cluster that codes for the biosynthesis of a novel antifungal polyketide with a glutarimide pharmacophore. Targeted gene inactivation, metabolic profiling, and bioassays led to the discovery of the gladiofungins as previously‐overlooked components of the antimicrobial armory of the beetle symbiont, which are highly active against the entomopathogenic fungus Purpureocillium lilacinum. By mutational analyses, isotope labeling, and computational analyses of the modular polyketide synthase, we found that the rare butenolide moiety of gladiofungins deriv…

Sinkholes risk analysis: case history of Marsala (Sicily, Italy)

2006

Given the increasing phenomenon of Sinkholes all over Italy, the Gruppo Nazionale per la Difesa dalle Catastrofi Idrogeologiche (G.N.D.C.I) and the Dipartimento della Protezione Civile (D.P.C.), during 2004, started a plan called Sinkholes dedicated to the phenomena in Italy. The plan provides the publication of the database realized by the D.P.C. by means of the census of beyond 1000 cases scattered across the nation. The city of Marsala is strongly characterized by the presence of a great number of Calcarenite cavities. The material object of extraction is the Calcarenite di Marsala of the Pleistocene, frequently used in the construction of buildings. The presence of the underground cavit…