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showing 10 items of 1962 documents

Advancement flap in the management of chronic anal fissure: A prospective study

2012

Lateral internal sphincterotomy is the surgical treatment of choice of chronic anal fissure after failure of conservative measures. Several randomized trials identified an overall risk of incontinence of 10 % mostly for flatus. Fissurectomy is the most commonly used procedure to preserve the integrity of the anal sphincters. However, a possible complication is keyhole defect that may lead to faecal soiling. In this study, chronic anal fissure (CAF) was treated by fissurectomy and anal advancement flap to preserve the anatomo-functional integrity of sphincters and to reduce healing time and the risk of anal stenosis. In patients with hypertonia, surgical treatment was combined with chemical …

AdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentInjections IntramuscularSurgical FlapsFissurectomyFollow-Up StudieInternal anal sphincterAnal stenosismedicineDeformityHumansReconstructive Surgical ProcedureProspective StudiesKeyhole defectBotulinum Toxins Type ADigestive System Surgical ProceduresAdvancement flapAgedNeuromuscular Agentbusiness.industryUrinary retentionDigestive System Surgical ProcedureRecovery of FunctionPlastic Surgery ProceduresMiddle AgedSurgerySurgical FlapProspective StudieSettore MED/18 - Chirurgia GeneraleTreatment OutcomeNeuromuscular AgentsAnesthesiaChronic DiseaseDefecationHypertoniaFemaleSurgeryFissure in AnoAdvancement flap; Chronic anal fissure; Fissurectomy; Adolescent; Adult; Aged; Botulinum Toxins Type A; Chronic Disease; Digestive System Surgical Procedures; Female; Fissure in Ano; Follow-Up Studies; Humans; Injections Intramuscular; Male; Middle Aged; Neuromuscular Agents; Prospective Studies; Reconstructive Surgical Procedures; Recovery of Function; Treatment Outcome; Surgical Flaps; Surgerymedicine.symptombusinessLateral internal sphincterotomyChronic anal fissureFollow-Up StudiesHuman
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Effect of manual therapy versus proprioceptive neuromuscular facilitation in dynamic balance, mobility and flexibility in field hockey players. A ran…

2018

To compare the effectiveness of a specific Manual Therapy (MT) protocol applied to field hockey players (FHP), versus a Proprioceptive Neuromuscular Facilitation (PNF) protocol, in the improvement of dynamic balance, active range of movement and lumbar flexibility one-week and four-weeks after the treatment.Randomized controlled trial. Participants were assigned to 2 groups: MT and PNF. 30 min' sessions were performed once a week for three weeks. Three evaluations were performed: basal, one-week and four-weeks post-treatment.University of Valencia (Spain).22 in MT group and 20 in PNF group.Dynamic Balance, measured with Star Excursion Balance Test; Active Range of Motion (ROM), using a manu…

AdultMalemedicine.medical_specialtyFlexibility (anatomy)Field hockeyAdolescentPhysical Therapy Sports Therapy and Rehabilitationlaw.invention03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationRandomized controlled triallawMuscle Stretching ExercisesmedicineHumansOrthopedics and Sports MedicineKneeRange of Motion ArticularDynamic balancePostural Balance030222 orthopedicsHipProprioceptionArthrometry Articularbusiness.industryLumbosacral Region030229 sport sciencesGeneral MedicineProprioceptionMusculoskeletal ManipulationsBiomechanical Phenomenamedicine.anatomical_structureHockeyAthletesAthletic InjuriesFemaleManual therapyAnkleAnklebusinessRange of motionPhysical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
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Minimally invasive cerebral cavernoma surgery using keyhole approaches - solutions for technique-related limitations.

2009

Cavernomas are often small in size and located in difficultly accessible regions. Preoperative identification of the ideal surgical approach as well as the precise intraoperative implementation of the surgical plan are of critical importance for successful surgery. While aiming for minimally invasive surgical techniques and maximally effective cavernoma resection, we envisaged that employing a combination of precise and technically sophisticated virtual reality surgery planning, modern navigation systems with augmented reality features and endoscope-assisted surgical techniques should contribute to achieve this goal. Between December 2002 and November 2005, 66 patients were operated on for …

AdultMalemedicine.medical_specialtyHemangioma Cavernous Central Nervous SystemNeuronavigation610 Medicine & healthComplete resectionNeurosurgical Proceduressurgery planningResection10180 Clinic for NeurosurgeryMedicineHumansMinimally Invasive Surgical ProcedurescavernomaNeuronavigationRetrospective StudiesSurgical approachbusiness.industryBrain NeoplasmsSurgery planningEndoscopyGeneral Medicine2746 SurgerySurgery2728 Neurology (clinical)Treatment OutcomeFeature (computer vision)virtual realitySurgeryAugmented realityNeurology (clinical)businessKeyholeMinimally invasive neurosurgery : MIN
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Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the…

2004

Aims Patients with diabetes are at excessive risk of mortality and cardiovascular morbidity. Previous studies suggest that aspirin may be less effective in diabetic patients. In this multi-centre, randomized, double blind trial picotamide, a dual inhibitor of thromboxane A2 synthase and receptor, was compared with aspirin for the prevention of mortality and major cardiovascular events in diabetics with peripheral arterial disease (PAD). Methods and results A total of 1209 adults aged 40–75 years with type 2 diabetes and PAD were randomized to receive picotamide (600 mg bid) or aspirin (320 mg od) for 24 months. The cumulative incidence of the 2 years overall mortality was significantly lowe…

AdultMalemedicine.medical_specialtyPhthalic AcidsType 2 diabetesDiabeteGastroenterologyThromboxane A2Double-Blind MethodRisk FactorsInternal medicineDiabetes mellitusPeripheral arterial diseasemedicineRisk of mortalityHumansPicotamideCumulative incidenceGeneral NursingAgedPeripheral Vascular DiseasesAspirinAspirinbiologybusiness.industryAntiplatelet therapyantiplatelet therapy; aspirin; diabetes; peripheral arterial disease; picotamide; thromboxane synthase inhibitorsMiddle Agedmedicine.diseaseSurvival AnalysisSurgeryThromboxane synthase inhibitors Indexed keywordsRelative riskbiology.proteinFemaleThromboxane-A synthasePicotamideCardiology and Cardiovascular MedicinebusinessDiabetic AngiopathiesPlatelet Aggregation InhibitorsFollow-Up Studiesmedicine.drugEuropean Heart Journal
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Odontogenic tumors: a collaborative study of 218 cases diagnosed over 12 years and comprehensive review of the literature.

2015

Objectives: The objective of this study was to analyze the frequency and distribution of odontogenic tumors (OTs) in the Cappadocia region of Turkey, and to compare the findings with those reported in the literature. Study Design: The records of the Oral and Maxillofacial Surgery and Pathology Departments at Erciyes University, with histologic diagnosis of odontogenic tumors (based on the World Health Organization classification, 2005), over a 12-year period, were analyzed. The relative frequency of different types of tumors was also analyzed and compared with the literature. Results: OTs in the present study constituted 2.74% of all the 7,942 registered biopsies. A total of 218 cases of OT…

AdultMalemedicine.medical_specialtyTime Factorsgenetic structuresAdolescentTurkeyDentistryOdontologíaOdontogenic TumorsJaw neoplasmOdontogenic myxomaYoung AdultOdontomaMedicineHumansAmeloblastomaChildGeneral DentistryAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologybusiness.industryResearchOdontogenic tumorRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludDermatologyJaw NeoplasmsOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgerySurgeryKeratocystic Odontogenic TumorFemalebusinessMedicina oral, patologia oral y cirugia bucal
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A retrospective study of 370 patients with oral lichen planus in Turkey.

2012

Objectives: Although several detailed studies concerning the patient profile and clinical features of oral lichen planus have been undertaken all over the world in different populations, a similar study has not yet been conducted in a Turkish population. The purpose of this retrospective study was to describe the demographic and clinical characteristics of a group of patients with oral lichen planus in Turkey. Study Design: Charts of 370 patients, from the archive of Oral Diagnosis and Radiology Department of Marmara University Faculty of Dentistry (Istanbul, Turkey), with histologically confirmed clinical diagnosis of oral lichen planus in the period 1990-2010 were retrospectively reviewed…

AdultMalemedicine.medical_specialtyTurkish populationAdolescentTurkeyDentistryOdontologíaAsymptomaticYoung Adultstomatognathic systemmedicineHumansOral DiagnosisYoung adultskin and connective tissue diseasesGeneral DentistryAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologyintegumentary systembusiness.industryRetrospective cohort studyMean ageMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatologyCiencias de la saludstomatognathic diseasesOtorhinolaryngologyClinical diagnosisUNESCO::CIENCIAS MÉDICASSurgeryOral lichen planusFemaleResearch-Articlemedicine.symptombusinessLichen Planus OralMedicina oral, patologia oral y cirugia bucal
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Prevalence of dyslipidemia and associated risk factors in Turkish adults.

2013

Background and Objectives Dyslipidemia is a modifiable major risk factor for coronary heart disease. The objective of this study was to determine the prevalence of dyslipidemia among Turkish adults and its associations with other cardiovascular risk factors. Methods This study included 4309 people ages 20 to 83 years old from 7 provinces of Turkey. People from the city centers, districts, and villages were selected by a stratified sampling method. Weight, height, and waist and hip circumferences were measured. Blood samples were obtained to determine glucose, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides …

AdultMalemedicine.medical_specialtyWaistTurkeygenetic structuresEndocrinology Diabetes and MetabolismCoronary DiseaseBody Mass Indexchemistry.chemical_compoundHigh-density lipoproteinCholesterol Dyslipidemia High-density lipoprotein Low-density lipoprotein Prevalence Triglycerides TurkeyRisk FactorsInternal medicinePrevalenceInternal MedicinemedicineHumansRisk factorNational Cholesterol Education ProgramTriglyceridesAgedDyslipidemiasAged 80 and overNutrition and Dieteticsbusiness.industryCholesterolBody WeightCholesterol HDLnutritional and metabolic diseasesCholesterol LDLMiddle Agedmedicine.diseaseCholesterolBlood pressurechemistryPhysical therapyFemalelipids (amino acids peptides and proteins)Cardiology and Cardiovascular MedicinebusinessBody mass indexDyslipidemia
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Surgical Treatment of Extravasation Injuries

2005

The authors present their experience of treating anti-cancer drug extravasation by means of a composite surgical technique that consists of infiltration with physiological solution and hyaluronidase and subsequent manual aspiration of solutes alternated with profuse irrigation of the infiltrated area. In the immediate post-op we carry out a medical therapy that consists of calciparine and topic antibiotic and/or steroid creams. Since the year 2000 this technique has been used on 25 patients. We have had neither complications nor scars. Copyright 2005 Wiley-Liss, Inc Surgical treatment of extravasation injuries. Napoli P, Corradino B, Badalamenti G, Tripoli M, Vieni S, Furfaro MF, Cordova A,…

AdultMalemedicine.medical_specialtyantiblastictreatment KeyWords Plus:ANTITUMOR AGENTSextravasation injury; antiblastic; prevention; treatmentANTITUMOR AGENTS; APPROPRIATE MANAGEMENT; TISSUE EXTRAVASATION; HYALURONIDASE [Author Keywords]Drug ExtravasationTherapeutic irrigationScarsAntineoplastic AgentsTISSUE EXTRAVASATIONAPPROPRIATE MANAGEMENTCicatrixpreventionBiopsymedicineHumansCalciparineAuthor Keywords:extravasation injurySurgical treatmentTherapeutic IrrigationAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryBiopsy NeedleGeneral MedicineHYALURONIDASEMiddle Agedmedicine.diseaseHandExtravasationSurgeryAnti-Bacterial Agentsanticancer drugsTreatment OutcomeOncologyAnesthesiaSurgeryFemalemedicine.symptombusinessInfiltration (medical)Extravasation of Diagnostic and Therapeutic Materials
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Depression and physical health multimorbidity: primary data and country-wide meta-analysis of population data from 190 593 people across 43 low- and …

2017

BackgroundDespite the known heightened risk and burden of various somatic diseases in people with depression, very little is known about physical health multimorbidity (i.e. two or more physical health co-morbidities) in individuals with depression. This study explored physical health multimorbidity in people with clinical depression, subsyndromal depression and brief depressive episode across 43 low- and middle-income countries (LMICs).MethodCross-sectional, community-based data on 190 593 individuals from 43 LMICs recruited via the World Health Survey were analysed. Multivariable logistic regression analysis was done to assess the association between depression and physical multimorbidity…

AdultMalemedicine.medical_specialtymultimorbidityKey words DepressionAdolescentHealth StatusLogistic regressionGlobal HealthOdds03 medical and health sciencesYoung Adult0302 clinical medicinemedicineGlobal healthHumanslow- and middle-income countries030212 general & internal medicineSomatization disorderPsychiatryDeveloping CountriesApplied PsychologyDepression (differential diagnoses)AgedDepression low- and middle-income countries multimorbidity physical health psychiatryDepressive Disorderbusiness.industryDepressionMultimorbidityOdds ratioMiddle Agedmedicine.diseaseComorbiditypsychiatryPsychiatry and Mental healthCross-Sectional StudiesMeta-analysisFemalebusinessKey words Depression; low- and middle-income countries; multimorbidity; physical health; psychiatry; Applied Psychology; Psychiatry and Mental Healthphysical health030217 neurology & neurosurgeryDemographyPsychological medicine
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A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

2012

Serum lipid levels have been associated with cardiovascular diseases, metabolic syndrome and type II diabetes (Kannel et al., 1961; Miller & Miller, 1975; Pilia et al., 2006). Variation in lipids levels is highly influenced by heritable factors (Friedlander et al., 1997) and 95 loci have already been associated with levels of high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, triglycerides (TG) and total cholesterol (TC) in numerous study samples and replicated in various populations using genome-wide approaches (Aulchenko et al., 2008; Kathiresan et al., 2008; Kooner et al., 2008; Teslovich et al., 2010; Willer et al., 2008). However, the genetic associa…

AdultNetherlands Twin Register (NTR)Candidate genegenetiikkaPopulationkolesteroliMonozygotic twinLocus (genetics)Genome-wide association studyBiologyPolymorphism Single NucleotideArticle03 medical and health sciences0302 clinical medicineGenetic variation/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansAlleleGene–environment interactioneducationAllelesGenetics (clinical)Aged030304 developmental biologyAged 80 and overGenetics0303 health scienceseducation.field_of_studyperinnöllisyystiedeCholesterol HDLGTPase-Activating ProteinsObstetrics and Gynecologyta3141Twins MonozygoticMiddle AgedIntrons3. Good healthGenetic LociPediatrics Perinatology and Child HealthFemaleGene-Environment InteractionApolipoprotein A-II030217 neurology & neurosurgeryGenome-Wide Association Study
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