Search results for "Kind"
showing 10 items of 173 documents
Regulation of vascular function and inflammation via cross talk of reactive oxygen and nitrogen species from mitochondria or nadph oxidase—implicatio…
2020
Oxidative stress plays a key role for the development of cardiovascular, metabolic, and neurodegenerative disease. This concept has been proven by using the approach of genetic deletion of reactive oxygen and nitrogen species (RONS) producing, pro-oxidant enzymes as well as by the overexpression of RONS detoxifying, antioxidant enzymes leading to an amelioration of the severity of diseases. Vice versa, the development and progression of cardiovascular diseases is aggravated by overexpression of RONS producing enzymes as well as deletion of RONS detoxifying enzymes. We have previously identified cross talk mechanisms between different sources of RONS, which can amplify the oxidative stress-m…
A cluster randomized web-based intervention trial to reduce food neophobia and promote healthy diets among one-year-old children in kindergarten: stu…
2018
A child’s first years of life are crucial for cognitive development and future health. Studies show that a varied diet with a high intake of vegetables is positive for both weight and cognitive development. The present low intake of vegetables in children’s diets is therefore a concern. Food neophobia can be a barrier for vegetable intake in children. Our hypothesis is that interventions that can increase children’s intake of vegetables should be introduced early in life to overcome children’s neophobia. This study aims to develop, measure and compare the effect of two different interventions among one-year-old children in kindergartens to reduce food neophobia and promote healthy diets. Th…
Long-term effects of a cluster randomized controlled kindergarten-based intervention trial on vegetable intake among Norwegian 3-5-year-olds: the BRA…
2020
AbstractObjectiveTo report on long-term effects of a cluster randomized controlled kindergarten-based intervention trial, which aimed to increase vegetable intake among Norwegian preschool children (3–5 years at baseline). The effects of the intervention at follow-up 1 (immediately post-intervention) have previously been published. This paper presents the effects of the intervention from baseline to follow-up 2 (12 months post-intervention).ResultsParental consents were obtained for 633 out of 1631 eligible children (response rate 38.8%). The effects of the intervention from baseline to follow-up 2 were assessed by mixed-model analyses taking the clustering effect of kindergartens into acco…
Toward evidence-based severity assessment in rat models with repeated seizures: I. Electrical kindling
2018
Objective: Rodent epilepsy models can significantly contribute to our understanding of pathophysiological mechanisms and to validation of biomarker and target candidates. Evidence-based severity assessment is a presupposition for the ethical evaluation of animal experimentation allowances as well as for the development of efficacious refinement concepts. Methods: Aiming to improve our understanding of the impact of experimental procedures and repeated seizures, we have completed a comprehensive behavioral and biochemical analysis assessing various parameters that can inform about the influence of an electrical kindling paradigm on well-being in rats. Thereby, we have focused on the immediat…
Fostering Self-Compassion and Loving-Kindness in Patients With Borderline Personality Disorder: A Randomized Pilot Study
2016
The aim of this randomized pilot study is to investigate the effects of a short training programme in loving-kindness and compassion meditation (LKM/CM) in patients with borderline personality disorder. Patients were allocated to LKM/CM or mindfulness continuation training (control group). Patients in the LKM/CM group showed greater changes in Acceptance compared with the control group. Remarkable changes in borderline symptomatology, self-criticism and self-kindness were also observed in the LKM/CM group. Mechanistic explanations and therapeutic implications of the findings are discussed. Highlights: Three weeks of loving-kindness and compassion meditations increased acceptance of the pres…
The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperacti…
2008
Contains fulltext : 70708.pdf (Publisher’s version ) (Open Access) ABSTRACT: BACKGROUND: Low serotonergic (5-HT) activity correlates with increased impulsive-aggressive behavior, while the opposite association may apply to cognitive impulsiveness. Both types of impulsivity are associated with attention-deficit/hyperactivity disorder (ADHD), and genes of functional significance for the 5-HT system are implicated in this disorder. Here we demonstrate the separation of aggressive and cognitive components of impulsivity from symptom ratings and test their association with 5-HT and functionally related genes using a family-based association test (FBAT-PC). METHODS: Our sample consisted of 1180 o…
Executive functions in kindergarten children at risk for developmental coordination disorder
2018
Executive functioning (EF) is a key cognitive process for development. Little is known about EF in Kindergarten children at risk for developmental coordination disorder (DCD), despite this age being one of the most critical and intensive period of motor and cognitive development. In our investigation we compared EF in kindergarten children at risk for DCD with Typically Developing (TD) children. Participants were 36 Italian children, 18 at risk for DCD (9 boys and 9 girls) who had a mean age of 4.6 years and 18 TD (9 boys and 9 girls) who had a mean age of 4.6. Executive functions were measured by tasks targeting cold executive functioning (working memory, fluency, inhibitory control) and t…
Estudio del perfil oxidativo en el síndrome de Kindler
2014
El Síndrome de Kindler (SK) es una rara genodermatosis cuyas manifestaciones principales son atrofia y envejecimiento prematuro de la piel, fotosensibilidad y carcinoma de piel, síntomas que comparte con otros síndromes (p. ej. Síndrome de Werner) en los que se ha demostrado la implicación del estrés oxidativo; sin embargo, en el SK no ha sido estudiado previamente. En el SK se ha identificado una alteración del brazo corto del cromosoma 20, donde se encuentra el gen KIND-1 que codifica la proteína kindlina-1. La pérdida de función de este gen conduce a una disminución de la síntesis de la proteína kindlina-1, produciendo, a su vez, una reducción de la adhesión de la interfase dermis-epider…
Leptodora kindti (Focke) (Crustacea; Cladocera) bioloģija un loma saldūdens ekosistēmās
1993
Ievads 1. Leptodora kindti populācijas sezonālā dinamika un vertikālās migrācijas 1.1. Materiāli un metodika 1.2. Rezultāti un to apspriešana 1.2.1. L. kindti dzīves cikls, izmēri un auglība 1.2.2. L. kindti populācijas sezonālā dinamika 1.2.3. L. kindti diennakts vertikālās migrācijas 2. Leptodora kindti lineārā augšana un populācijas produktivitāte 2.1. Materiāli un metodika 2.2. Rezultāti un to apspriešana 2.2.1. L. kindti lineārās augšanas ātrums 2.2.2. L. kindti augšanas procesu īpatnības un populācijas produktivitātes rādītāju analīze 3. Leptodora kindti barošanās 3.1. Materiāli un metodika 3.2. Rezultāti un to apspriešana 3.2.1. Pieaugušo L. kindti barošanās 3.2.2. Juvenīlo L. kindti…
Fostering Self-Compassion and Loving-Kindness in Patients With Borderline Personality Disorder: A Randomized Pilot Study.
2017
The aim of this randomized pilot study is to investigate the effects of a short training programme in loving-kindness and compassion meditation (LKM/CM) in patients with borderline personality disorder. Patients were allocated to LKM/CM or mindfulness continuation training (control group). Patients in the LKM/CM group showed greater changes in Acceptance compared with the control group. Remarkable changes in borderline symptomatology, self-criticism and self-kindness were also observed in the LKM/CM group. Mechanistic explanations and therapeutic implications of the findings are discussed. Highlights: Three weeks of loving-kindness and compassion meditations increased acceptance of the pres…