Search results for "Kind"
showing 10 items of 173 documents
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
2013
AM Vicente - Cross-Disorder Group of the Psychiatric Genomics Consortium Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype data from the Psychiatric Genomics Consortium (PGC) for cases and controls in schizophrenia, bipolar disorder, major depressive disorder, autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). We apply univariate and bivariate methods for the estimation of genetic variation within and covariation between disorders. SNPs explained 17-29% of the variance in …
Impact of new teacher recruitment policies on development of educational systems in sub-Saharan Africa
2014
The development of Education systems in Sub-Saharan Africa as a whole and specially in Burkina Faso, Congo, Senegal shows ups and downs due to their low development, despite commitments made by the international community in 1990 at Jomtien in Thailand. The Dakar Forum in 2000, while recognizing progress recorded since independence for African countries,highlighted the need for States to undertake deep reforms with regard to education systems. Actually, since independence, the will shown by States to grant priority to education - as they are convinced that education has a positive impact on development of nations - was undermined by a number of uncertainties, including Structural Adjustment…
Reliability and validity evidence of the early numeracy test for identifying children at risk for mathematical learning difficulties
2020
Abstract This study investigated reliability and validity evidence regarding the Early Numeracy test (EN-test) in a sample of 1139 Swedish-speaking children (587 girls) in kindergarten (n = 361), first grade (n = 321), and second grade (n = 457). Structural validity evidence was established through confirmatory factor analysis (CFA), which showed that a four-factor model fit the data significantly better than a one-factor or two-factor model. The known-group and cross-cultural validity were established through multigroup CFAs, finding that the four-factor model fit the gender, age and language groups equally well. Internal consistency for the test and sub-skills varied from good to excellen…
Parent of origin effects in attention/deficit hyperactivity disorder (ADHD): analysis of data from the international multicenter ADHD genetics (IMAGE…
2008
Contains fulltext : 71540.pdf (Publisher’s version ) (Closed access) There are conflicting reports suggesting that the parental origin of transmitted risk alleles may play a role in the etiology of attention deficit/hyperactivity disorder (ADHD). A recent report by Hawi and colleagues observed a generalized paternal over-transmission of alleles associated with ADHD. This was not replicated in more recent studies. Using data from a large multicenter study we examined the overall and gene-specific parent of origin effect in 554 independent SNPs across 47 genes. Transmission disequilibrium and explicit parent of origin test were performed using PLINK. Overall parent of origin effect was tested…
Physical Activity Among Children With Congenital Heart Defects in Germany: A Nationwide Survey
2020
Objective: In children with congenital heart defects (CHD), a sedentary lifestyle should be avoided and usually WHO recommendations on physical activity (PA) are supposed to be followed. In order to obtain representative data of the actual amount of PA (and potential influencing factors) in children with CHD we performed a nationwide online survey.Methods: All patients aged 6–17 years registered in the German National Register for CHD were contacted by email and asked to participate in the survey using the comprehensive questionnaire of the “Motorik-Modul” from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS), thus allowing the comparison with a repres…
Epoch Parameterization by Gabor Atom Density in Experimental Epilepsy
2007
An Electrocorticogram (ECoG), during an epilepsy episode can change dramatically from the normal state into a high amplitude low frequency signal and suddenly return to the normal sate. It is possible to identify some stages in the epilepsy seizure, the most representative of them: basal, preictal, ictal and posictal. ECoG are highly non periodical signals, so they are analyze with T-F algorithms, in order to follow up its frequency evolution through the seizure stages. Each seizure stage has different frequency components and they show up at different time. Experimental epilepsy produce by kindling model in rats is used; signals are recorded at cortex level. The ECoG is decompose by means …
Impact of a temporal sinusoidal phase modulation on the optical spectrum
2018
International audience; We discuss the effects of imparting a temporal sinusoidal phase modulation to a continuous wave on the frequency spectrum. While a practical analytical solution to this problem already exists, we present here a physical interpretation based on interference processes. This simple model will help the students better understand the origin of the oscillatory structure that can be observed in the resulting spectrum and that is characteristic of Bessel functions of the first kind. We illustrate our approach with an example from the field of optics.
"In den Tiefen wird alles Gesetz"… Przyczynek do dziejów literackiego motywu jaskini
2020
In the course of history, the cave, a natural geological void, has acquired its semantic richness in anthropology, religion, philosophy and culture, its major connotation relating to the journey to the inside of the Earth. In the literature from the ancient times up to the present we can distinguish various realizations of the motifs of the nether regions, caves, grottos or caverns, but out of this variety emerge three basic symbolic orientations: “the caves of subconscious”, “the grottos of birth” and “the metaphysical caverns”. The overview of the most interesting examples of the classic and contemporary European epic works (A. Pope’s The Rape of the Lock; J. W. Goethe’s Faust; A. Stifter…
Oxidative stress and mitochondrial dysfunction in Kindler syndrome
2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.
Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other…
2008
Contains fulltext : 69677.pdf (Publisher’s version ) (Closed access) A major goal of genetic studies of attention deficit hyperactivity disorder (ADHD) is to identify individual characteristics that might help segregate the disorder's inherent heterogeneity. [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] recently reported a potentially important association between two dopamine-related risk polymorphisms (DRD4 variable number tandem repeat (VNTR) in exon 3 and DAT1 VNTR in the 3' UTR) and lowered IQ in ADHD. The objective of the current study was to replicate the [Mill et al. (2006); Arch Ger Psychiatry 63:462-469] findings in a clinical sample and to extend the analysis to a large ra…