Search results for "Kindle"

showing 4 items of 4 documents

Estudio del perfil oxidativo en el síndrome de Kindler

2014

El Síndrome de Kindler (SK) es una rara genodermatosis cuyas manifestaciones principales son atrofia y envejecimiento prematuro de la piel, fotosensibilidad y carcinoma de piel, síntomas que comparte con otros síndromes (p. ej. Síndrome de Werner) en los que se ha demostrado la implicación del estrés oxidativo; sin embargo, en el SK no ha sido estudiado previamente. En el SK se ha identificado una alteración del brazo corto del cromosoma 20, donde se encuentra el gen KIND-1 que codifica la proteína kindlina-1. La pérdida de función de este gen conduce a una disminución de la síntesis de la proteína kindlina-1, produciendo, a su vez, una reducción de la adhesión de la interfase dermis-epider…

:CIENCIAS MÉDICAS ::Ciencias clínicas::Dermatología [UNESCO]estrés oxidativoUNESCO::CIENCIAS MÉDICAS ::Ciencias clínicas::Dermatologíakindlinaskindler
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Clinical practice guidelines: Oral health care for children and adults living with epidermolysis bullosa.

2020

Background Inherited epidermolysis bullosa (EB) is a genetic disorder characterized by skin fragility and unique oral features. Aims To provide (a) a complete review of the oral manifestations in those living with each type of inherited EB, (b) the current best practices for managing oral health care of people living with EB, (c) the current best practices on dental implant-based oral rehabilitation for patients with recessive dystrophic EB (RDEB), and (d) the current best practice for managing local anesthesia, principles of sedation, and general anesthesia for children and adults with EB undergoing dental treatment. Methods Systematic literature search, panel discussion including clinical…

AdultSpecial Issue Articlesmedicine.medical_specialtymedicine.medical_treatmentBest practiceAnesthesia DentalOral Healthepidermolysis bullosa simplexrecessive dystrophic epidermolysis bullosadystrophic epidermolysis bullosa03 medical and health sciencesWound care0302 clinical medicineQuality of life (healthcare)junctional epidermolysis bullosadental treatmentdental implantsmedicineHumansLocal anesthesia030212 general & internal medicineepidermolysis bullosaChildGeneral DentistryRehabilitationbusiness.industryoral care030206 dentistryGuidelinekindler epidermolysis bullosamedicine.diseasegeneral anesthesiaEpidermolysis Bullosa Dystrophicastomatognathic diseasesSystematic reviewsedationoral rehabilitationFamily medicinePractice Guidelines as TopicQuality of LifeEpidermolysis bullosabusinessclinical practice guidelineSpecial care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
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Skaidrojošās vārdnīcas Tezaurs.lv mobilie lietojumi

2019

Šodien, vairāk kā jebkad, mēs informāciju iegūstam mobilajās ierīcēs, tādēļ ir vērts padarīt maksimāli lielu daļu digitālās informācijas tām pieejamu. Tezaurs.lv ir lielākā atvērto datu latviešu valodas vārdnīca un tā korekti attēlojas tikai ierīcēs ar lieliem ekrāniem. Šī darba mērķis ir padarīt Tēzauru pieejamu un ērti lietojamu mobilajās ierīcēs. Darbā tiek analizēta vietnes lietotāju statistika, lai noteiktu prasības; rīkā Sketch izveidots interaktīvs saskarnes prototips; pašreizējā vietne pārveidota par reaģējošu; satvarā Adobe PhoneGap izveidota Android lietotne, kā arī Tēzaura bezsaistes dati pārveidoti par MOBI vārdnīcu lietojumam Kindle e-lasītājos, kas ir pirmā šāda veida vārdnīca…

Datorzinātnee-lasītājsKindlevārdnīcareaģējošs dizainsPhoneGap
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Oxidative stress and mitochondrial dysfunction in Kindler syndrome

2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.

Premature agingMaleKeratinocytesAdolescentComputingMilieux_LEGALASPECTSOFCOMPUTINGMitochondrionmedicine.disease_causePathogenesisKindler syndrome03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBlistermedicineHumansGenetics(clinical)Pharmacology (medical)Photosensitivity DisordersGenodermatosisChildGenetics (clinical)Cells CulturedPeriodontal Diseases030304 developmental biologyAged 80 and overMedicine(all)0303 health sciencesintegumentary systemResearchGeneral MedicineGlutathioneMiddle Agedmedicine.diseaseMalondialdehydeMolecular biology3. Good healthMitochondriaOxidative StresschemistryOxidative stress030220 oncology & carcinogenesisChild PreschoolFemaleSkin cancerEpidermolysis BullosaKindlin1Oxidative stressOrphanet Journal of Rare Diseases
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