Search results for "L-aspartate"

showing 3 items of 3 documents

PRELIMINARY-OBSERVATIONS OF METABOLIC CHARACTERIZATION OF BILATERAL TEMPORAL EPILEPTIC FOCUS, USING PROTON MAGNETIC-RESONANCE SPECTROSCOPY - 3 CASES

1994

International audience; Abstract: The authors report the case of 3 patients with bilateral temporal lobe epilepsy demonstrated by EEG and sphenoidal electrodes. Two out of the 3 patients presented with childhood febrile convulsions. Their neurological and mental examination was normal. EEG showed spikes within the anterior part of the 2 temporal lobes. CT scan and MRI showed no atrophic lesion within the 2 temporal lobes. Proton magnetic resonance spectroscopy, performed within a cube of 8 cube-centimetres localized in the anterior part of the 2 temporal lobes showed a significant decrease of N-acetyl-aspartate in the 2 temporal lobes of the 3 cases, compared with controls matched with age,…

PROTON SPECTROSCOPY[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingN-ACETYL-ASPARTATE[INFO.INFO-IM]Computer Science [cs]/Medical Imaging[INFO.INFO-IM] Computer Science [cs]/Medical ImagingTEMPORAL SEIZURES
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Binuclear Cu2+ complex mediated discrimination between L-glutamate and L-aspartate in water.

2005

L-Glutamate and L-aspartate selectivity is achieved by the action of two Cu2+ metal ions rightly disposed in a cyclophanetype macrocyclic framework; electrochemical sensing of glutamate has been achieved by adsorption of the copper complexes on graphite electrodes. Verdejo Viu, Begoña, Begona.Verdejo@uv.es ; Domenech Carbo, Antonio, Antonio.Domenech@uv.es ; Jimenez Garcia, Hermas Rafael, Hermas.Jimenez@uv.es ; Soriano Soto, Concepción, Concepcion.Soriano@uv.es ; Garcia-España Monsonis, Enrique, Enrique.Garcia-Es@uv.es

StereochemistryUNESCO::QUÍMICAMetal ions in aqueous solutionL-Aspartatechemistry.chemical_elementGlutamic AcidElectrochemistry:QUÍMICA [UNESCO]Medicinal chemistryCatalysisAdsorptionMaterials ChemistryElectrochemistryOrganometallic CompoundsAspartic AcidUNESCO::QUÍMICA::Química inorgánicaElectrochemicalMetals and AlloysGlutamate receptorWaterBinuclear Cu2General ChemistryCyclophanetype macrocyclic framework:QUÍMICA::Química inorgánica [UNESCO]CopperSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryL glutamateL-aspartateBinuclear Cu2 ; L-glutamate ; L-aspartate ; Water ; Cyclophanetype macrocyclic framework ; ElectrochemicalCeramics and CompositesL-glutamateSelectivityCopperChemical communications (Cambridge, England)
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Reduced brain N-acetyl-aspartate in frontal lobes suggests neuronal loss in patients with amyotrophic lateral sclerosis

1996

International audience; Abstract: We performed proton magnetic resonance spectroscopy (IH-MRS) in three patients with amyotrophic lateral sclerosis (ALS) to evaluate the distribution and extent of cortical neuronal damage as demonstrated by decreased N-acetyl-aspartate (NAA) levels. We examined primary motor (precentral gyrus) and parietal neocortical (superior parietal gyrus) regions. ALS was defined with lower and upper motor neuron signs. Compared with matched healthy controls, ALS patients had a significant decrease in NAA levels in the primary motor cortex (p<0.001) compared with parietal regions and homologous regions in healthy controls. Two clinical applications can be extracted: fi…

amyotrophic lateral sclerosis[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingnervous system[INFO.INFO-IM]Computer Science [cs]/Medical Imaging[INFO.INFO-IM] Computer Science [cs]/Medical ImagingN-acetyl-aspartateneuron
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