Search results for "LAB"
showing 10 items of 7932 documents
Demonstration of endogenous lectins in synovial tissue.
1991
We have recently shown that synoviocytes and extracellular matrices exhibit distinct patterns of carbohydrate expression. Their biological relevance is however not known. The purpose of the present study was to find out whether human synovial tissue would also show a specific receptor pattern for complex sugar molecules. Endogenous lectins were displayed by means of biotinylated neoglycoproteins and sulfated polysaccharides in paraffin-embedded material or cryosections. In addition to certain carbohydrate components that are known to be constituents of the carbohydrate part of cellular glycoconjugates, our panel included heparin and fucoidan, a sulfated fucose. Binding sites were shown usin…
A constitutively active pituitary adenylate cyclase activating polypeptide (PACAP) type I receptor shows enhanced photoaffinity labeling of its highl…
2001
Abstract In the present study, we have analyzed a previously identified constitutively active pituitary adenylate cyclase activating polypeptide (PACAP) type I (PAC1) receptor with a deletion of the single amino acid residue Glu 261 (Y.-J. Cao, G. Gimpl, F. Fahrenholz, A mutation of second intracellular loop of pituitary adenylate cyclase activating polypeptide type I receptor confers constitutive receptor activation, FEBS Lett. 469 (2000)). This glutamic acid residue is highly conserved within the second intracellular loop of class II G protein-coupled receptors and may thus be of importance for many members of this receptor class. To explore the molecular characteristics of this mutant re…
Global distributions of diazotrophs abundance and biomass - Depth integrated values computed from a collection of source datasets - Contribution to t…
2013
The MAREDAT atlas covers 11 types of plankton, ranging in size from bacteria to jellyfish. Together, these plankton groups determine the health and productivity of the global ocean and play a vital role in the global carbon cycle. Working within a uniform and consistent spatial and depth grid (map) of the global ocean, the researchers compiled thousands and tens of thousands of data points to identify regions of plankton abundance and scarcity as well as areas of data abundance and scarcity. At many of the grid points, the MAREDAT team accomplished the difficult conversion from abundance (numbers of organisms) to biomass (carbon mass of organisms). The MAREDAT atlas provides an unprecedente…
Global distributions of diazotrophs nitrogen fixation rates - Depth integrated values computed from a collection of source datasets - Contribution to…
2013
The MAREDAT atlas covers 11 types of plankton, ranging in size from bacteria to jellyfish. Together, these plankton groups determine the health and productivity of the global ocean and play a vital role in the global carbon cycle. Working within a uniform and consistent spatial and depth grid (map) of the global ocean, the researchers compiled thousands and tens of thousands of data points to identify regions of plankton abundance and scarcity as well as areas of data abundance and scarcity. At many of the grid points, the MAREDAT team accomplished the difficult conversion from abundance (numbers of organisms) to biomass (carbon mass of organisms). The MAREDAT atlas provides an unprecedente…
Pastāvošā stāvokļa analīze Eirāzijas cietuma kapelānu profesionālo vajadzību noteikšanai
2020
Pētījums veikts ar mērķi veikt Eirāzijas cietumu kapelānu situācijas analīzi, lai sekmīgi apzinātu cietuma kapelānu vajadzības gan pašreizējā, gan turpmākajā attīstības posmā. Darbības pētījumā tika izmantoti mērķu-orientētas projekta plānošanas un loģiskās struktūras pieejas koncepti un iesaistīti dalībnieki no sešiem Eirāzijas reģioniem. Darba pētījumā tika pielietotas šādas datu vākšanas metodes - intervija, dienasgrāmatu piezīmes, anketēšana, dokumentu analīze, kā arī veikta ieinteresēto personu (cietuma kapelānu) un problēmu tabulas analīze. Literatūras izpētē un darbības pētījuma rezultātos redzama savstarpēja atbilstība, kas norāda uz precīzu cietuma kapelāna personisko un profesionā…
Improving marine protected area governance through collaboration and co-production.
2020
Marine protected areas (MPAs) socio-ecological effectiveness depends on a number of management and governance elements, among which stakeholder engagement and community support play key roles. Collaborative conservation initiatives that engage stakeholders in action research and knowledge co-production processes can enhance management and governance of MPAs. To design effective strategies aimed at reconciling biodiversity conservation and management of sustainable human uses, it is key to assess how local communities respond to such initiatives and identify the set of contextual factors, institutional, local and individual, potentially affecting these responses. This paper presents the appr…
Gospelmūzikas tradīcija Latvijā
2017
Mūzika ir viens no pirmatnējiem komunikācijas veidiem cilvēku starpā. Mūsdienās par nozīmīgu kristīgās dziedāšanas un muzicēšanas formu izveidojies gospels. Lai arī gospelmūzikas saknes meklējamas Amerikas Savienotu Valstu konkrēta laikaposma politiskajā un kultūrvidē, tai piemīt saturs un izteiksmes līdzekļi, kas spēj uzrunāt mūsdienu cilvēku visā pasaulē, arī Latvijā. Savā bakalaura darbā “Gospelmūzikas tradīcija Latvijā” sniedzu ieskatu par mūzikas saistību ar teoloģiju, mūzikas praktizēšanu Bībelē, gospelmūzikas izcelšanos un attīstību līdz mūsdienām, kā arī gospelmūzikas ienākšanu un tās izpausmes gospelkoros Latvijā. Darba mērķis ir izpētīt gospelmūzikas ienākšanu un praksi Latvijā lī…
EUROPE 2020 SI-LAB: A New Center for Economic and Social Development in Sicily
2014
The debate on the determinants of regional and local development has been stimulated recently by the European strategy for smart, sustainable and inclusive growth defined as Europe 2020. We present the objectives and structure of a new laboratory (SI-LAB) for the development of Sicilian economy promoted by the University of Palermo. In particular, we highlight the fundamental issues related to the incoming functioning of the Lab as a new oganization devoted to analyzing public policy issues, and fostering new ways of entrepreurship at the local level.
Enhancing policy design and sustainable community outcomes through collaborative platforms based on a dynamic performance management and governance a…
2022
This chapter aims at illustrating how a Dynamic Performance Management and Governance approach may support the implementation of “collaborative platforms” (Ansell and Gash, 2018) to enhance network policy design and the pursuit of sustainable community outcomes. This is an emerging field of research, embracing performance management, collaborative governance, and systems theory, aimed at fostering a learning-oriented perspective in performance data use. Such a view has been also referred as “collaborative performance management”, i.e., the “sharing of resources and information among different actors for the purposes of achieving a formal performance goal” (Choi and Moynihan, 2019, p. 1539).…
Household Debt and Fiscal Multipliers
2015
We study the size of government spending multipliers in a general equilibrium model with search and matching frictions in which we allow for different levels of household indebtedness. The main results of the paper are: (a) the presence of impatient households and private debt helps generate government spending multipliers greater than 1; (b) as financial conditions worsen and impatient consumers find it more difficult to borrow (i.e. in a credit crunch), the size of the government spending multiplier falls; (c) conversely, employment, vacancies and unemployment multipliers are larger when access to credit becomes more difficult; and (d) the model explains the observed pattern of responses …