Search results for "LAB"
showing 10 items of 7932 documents
Relationships between burnout and role ambiguity, role conflict and employee absenteeism among health workers
2014
The aim of this research was to analyze the influence of some psychosocial risk factors in the development of burnout and to analyze the influence of this phenomenon on employee absenteeism. The study sample included 142 health care workers. The data analysis included descriptive statistics and multiple linear regression models. The results confirmed the influence of role ambiguity and role conflict on burnout [F (2.139) = 26.720; p < .001], but the influence of burnout on employee absenteeism was not confirmed. However, a significant and positive relationship has been shown between burnout and employee absenteeism (ß = 0.197; p < .05). In conclusion, the findings of this study support the …
Les empreses familiars de comercialització de cítrics: el retrat d'una època i d'una societat agrària
2009
Domingo Perez, Concepcion - Concepcion.Domingo@uv.es L'àmbit tradicional dels cítrics valencians estava configurat per tres elements bàsics: unes explotacions agràries de reduïdes dimensions, les empreses de comercialització, la major part de les quals de tipus familiar, i les peculiars relacions laborals amb els assalariats, homes i dones, en gran part també xicotets propietàris locals. Esta organització, vinculava estretament els productors agraris, les empreses comercials i els assalariats. La seua decadència suposa molt més que la desaparició de moltes empreses familiars: pot ser la fi d'un gran sistema socio-econòmic desenvolupat amb èxit durant les dècades centrals del segle vint.
Mapping a-priori defined plant associations using remotely sensed vegetation characteristics
2014
Abstract Incorporation of a priori defined plant associations into remote sensing products is a major challenge that has only recently been confronted by the remote sensing community. We present an approach to map the spatial distribution of such associations by using plant indicator values (IVs) for salinity, moisture and nutrients as an intermediate between spectral reflectance and association occurrences. For a 12 km 2 study site in the Netherlands, the relations between observed IVs at local vegetation plots and visible and near-infrared (VNIR) and short-wave infrared (SWIR) airborne reflectance data were modelled using Gaussian Process Regression (GPR) (R 2 0.73, 0.64 and 0.76 for sali…
In vitro evaluation of glycol chitosan based formulations as oral delivery systems for efflux pump inhibition.
2017
Recently, we have reported that glycol chitosan (GCS) was able to reverse the P- glycoprotein (P-gp) efflux pump. The objective of the present study was to evaluate the potential of two GCS-based dosage forms (aqueous solution or nanoparticle suspension) for oral administration of the P-gp substrate Rho-123. A further aim of the present study was to assess the effect of the glycol chitosan-4-thiobutylamidine thiomer (GCS-TBA) on P-gp activity considering that the corresponding thiomer of chitosan series is a well-known P-gp inhibitor. Pre-treatment of Caco-2 cell monolayer with a GCS solution or GCS-based nanoparticles increased the absorptive transport of Rho-123 across the monolayer of 1.…
Electron microscopic immunogold cytochemistry reveals chromogranin A confined to secretory granules of porcine Merkel cells
1990
By ultrastructural immunohistochemistry using the immunogold technique, immunoreactive (ir) Chromogranin A (CGA) was found to be confined to the secretory vesicles of porcine Merkel cells. CGA was present predominantly in the periphery of the electron-dense core and on the clear halo. These findings indicate that CGA is a regular constituent of Merkel cell secretory granules but probably not exclusively responsible for their electron opacity.
Ocular gelling microspheres: in vitro precorneal retention time and drug permeation through reconstituted corneal epithelium.
2008
Purpose: The model drug norfloxacin (NOR)was encapsulated into trehalose (TRH) and hydroxyethylcellulose(NAT) microspheres to obtain a novel gelling ophthalmic delivery system for prolonged release on corneal tissue. Methods: We assessed NOR release from microspheres, prepared by the emulsion-solvent evaporation method. A new in vitro tear turnover model, including inserts containing reconstituted human corneal epithelium (RHC), was designed to evaluate the TRH/NAT microspheres’ precorneal retention time. Bioadhesive properties of TRH/NAT microspheres were validated by using drug-loaded microspheres prepared with gelatine (GLT) commonly used as reference material in adhesion studies. Result…
Trigeminal innervation of the mammalian pineal gland.
1999
There is evidence that the trigeminal (Gasserian) ganglia innervate the mamma- lian pineal gland and serve in its regulation in addition to the sympathetic and cholinergic as well as further influences. By means of immunohistochemical methods, previous studies demonstrated fibers containing calcitonin gene-related peptide (CGRP-LI) or substance P (SP) in the superficial pineal of various mammalian species. In addition, SP and the related tachykinin, neurokinin A, were detected by radioimmunoassay and HPLC, respectively, in the rat and human pineal gland. In the present study, retrograde neuronal tracing upon injection of a tracer substance into the superfical pineal gland of rats was used i…
Photo-DHEA--a functional photoreactive dehydroepiandrosterone (DHEA) analog.
2011
Abstract The steroid hormone dehydroepiandrosterone (DHEA) has beneficial effects on vascular function, survival of neurons, and fatty acid metabolism. However, a specific receptor for DHEA has not been identified to date. Here, we describe the synthesis of a photoreactive DHEA derivative (Photo-DHEA). In Photo-DHEA, typical characteristics of DHEA are conserved: (i) a “planar” tetracyclic ring system with a Δ 5 double bond, (ii) a 3β-hydroxyl group, and (iii) a keto group at C17. In cell-based assays, Photo-DHEA showed the same properties as DHEA. We conclude that Photo-DHEA is suitable for radioiodination to yield a tool for the identification of the elusive DHEA receptor.
Tiroiditis de Hashimoto: Microcirculación Lingual y Labial en Pacientes Afectados por Macroglosia
2007
The aim of this study is to estudy lingual and labial microcirculation differences among healthy subjects and those with Hashimoto's thyroiditis affected by macroglossia. Twenty healthy patients and 20 patients suffering from Hashimoto's thyroiditis were examined. Labial and lingual capiUaroscopy were used to investigate the characteristics of microcirculation. For each patient we evaluated visibility, course, tortuosity and the possible presence of microhaemorrhages, average calibre of capillary loops and the number of visible capillary loops per square millimetre. The investigations of the labial and lingual mucous were simple, non invasive and repeatable for each patient. In Hashimoto's …
Risk of Low Energy Availability, Disordered Eating, Exercise Addiction, and Food Intolerances in Female Endurance Athletes
2022
Relative energy deficiency in sport (RED-S) is a complex syndrome describing health and performance consequences of low energy availability (LEA) and is common among female endurance athletes. Various underlying causes of LEA have been reported, including disordered eating behavior (DE), but studies investigating the association with exercise addiction and food intolerances are lacking. Therefore, the aim of this cross-sectional study was to investigate the association between DE, exercise addiction and food intolerances in athletes at risk of LEA compared to those with low risk. Female endurance athletes, 18–35 years, training ≥5 times/week were recruited in Norway, Sweden, Ireland, and Ge…