Search results for "LAB"

showing 10 items of 7932 documents

Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging.

2017

Background In this work, the in vitro and in vivo stabilities and the pharmacology of HPMA-made homopolymers were studied by means of radiometal-labeled derivatives. Aiming to identify the fewer amount and the optimal DOTA-linker structure that provides quantitative labeling yields, diverse DOTA-linker systems were conjugated in different amounts to HPMA homopolymers to coordinate trivalent radiometals Me(III)* = gallium-68, scandium-44, and lutetium-177. Results Short linkers and as low as 1.6% DOTA were enough to obtain labeling yields > 90%. Alkoxy linkers generally exhibited lower labeling yields than alkane analogues despite of similar chain length and DOTA incorporation rate. High sta…

lcsh:Medical physics. Medical radiology. Nuclear medicinelcsh:R895-920Gallium-68610 MedizinDOTA-HPMA conjugatesPETBiodistributionTheranostic610 Medical sciencesScandium-44Lutetium-177neoplasmsOriginal ResearchRadiolabelingEJNMMI research
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Image Segmentation Techniques for Healthcare Systems

2019

The present special issue of the Journal of Healthcare Engineering collects articles written by researchers scattered around the world who belong to the academic and industrial environments. The papers of this special issue have been selected by a rigorous peer-reviewing process with the support of at least two reviewers per paper, along with the opinion written in the final decision by a component of the editorial staff. Different methods on biomedical image segmentation dedicated to healthcare systems have been developed regarding, for example, the fields of machine learning, deformable models, fuzzy models, and so on. Such methods have been applied on different biomedical image modalitie…

lcsh:Medical technologyArticle SubjectComputer scienceBiomedical EngineeringMEDLINEHealth InformaticsImage processingImage Interpretation Computer-AssistedImage Processing Computer-AssistedHumansComputer visionSettore ING-INF/05 - Sistemi Di Elaborazione Delle Informazionilcsh:R5-920Settore INF/01 - Informaticabusiness.industrySegmentation Healthcare Remote Support Medical Imaging Diagnosis Support SystemsImage segmentationEditoriallcsh:R855-855.5Settore ING-INF/06 - Bioingegneria Elettronica E InformaticaSurgeryArtificial intelligencebusinesslcsh:Medicine (General)Delivery of Health CareBiotechnologyHealthcare systemJournal of Healthcare Engineering
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Design and Culture of the Territory: Ecomuseo del Grano e del Pane in the Salemi Museum System

2019

The article deals with design experimentation in the complex and composite field of design for the culture of the territory, aimed at enhancing the particular resources common to the Mediterranean areas, through an incremental and collaborative design methodology. The town of Salemi (TP) inherited an extraordinary concentration of cultural heritage from its history; in particular the preparation and display of the decorated breads for the Festivity of San Giuseppe, occurring on March 19th, which expresses a profound religiosity and a complex rituality, shared, handed down and recognized as an intan- gible cultural asset to be protected. In this territorial context, a vision aimed at encour-…

lcsh:NC1-1940participatory action researchcollaborative designlcsh:Drawing. Design. IllustrationSettore ICAR/13 - Disegno IndustrialeecomuseumParticipatory Action Research.culture of the territorylcsh:NA2695-2793lcsh:Architectural drawing and designdesign for cultural heritagePad
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Diferencias sexuales en el aprendizaje del Laberinto Hebb-Williams con ratones OF1

2017

espanolEl Laberinto Hebb-Williams es una prueba utilizada para evaluar el aprendizaje espacial en animales. Aunque la capacidad espacial es una funcion cognitiva considerada sexodimorfica, donde los machos muestran una ventaja frente a las hembras, los resultados de los pocos estudios que evaluen diferencias de sexo en esta prueba no son concluyentes. Por ello, en este estudio nos propusimos comprobar si los ratones OF1 machos ejecutaban mejor que las hembras las tareas del Laberinto Hebb-Williams, y si esa ventaja era independiente de la dificultad del laberinto. Se utilizo la version reducida para ratones, la cual consta de 5 laberintos, 3 consi-derados faciles y 2 dificiles. Los resultad…

lcsh:PsychologyAprendizaje espacialRatonesaprendizaje espaciallcsh:Blcsh:BF1-990General Medicinediferencias sexualesratonesLaberinto Hebb-WilliamsDiferencias sexualeslcsh:Philosophy. Psychology. ReligionEscritos de Psicología - Psychological Writings
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Cómo conseguir mejorar el aprendizaje de palabras

2019

Muchas de las palabras que conocemos no han sido adquiridas mediante un esfuerzo explícito, sino de manera incidental. Pero se sabe relativamente poco sobre los factores que modulan el aprendizaje implícito de vocabulario. Varios experimentos recientes han mostrado que las palabras nuevas se adquieren mejor cuando se aprenden en diferentes contextos que en un mismo contexto. Estos hallazgos apoyan la idea de organizar un currículo educativo transversal que mejore la adquisición de vocabulario tanto en la lengua materna (v.g., a través de diferentes asignaturas) como en otras lenguas.

lcsh:Psychologyaprendizaje de palabraslcsh:BF1-990diversidad contextuallcsh:Consciousness. Cognitionlcsh:BF309-499aprendizaje incidental
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Evaluación de la efectividad de las actividades preventivas (planes de actuación preferente) sobre la incidencia de las lesiones traumáticas no morta…

2007

Fundamento. Los planes de actuación preferente (PAP) han sido las principales actividades preventivas desarrolladas por las comunidades autónomas (CCAA) frente a las lesiones por accidentes de trabajo (LAT) en España desde 1999. El objetivo de este trabajo es evaluar la efectividad de los planes. Métodos. Fueron seleccionados 4.714.080 casos incidentes de LAT no mortales con incapacidad laboral, ocurridos entre 1994 y 2004 durante la jornada laboral producidos por causas mecánicas y por sobreesfuerzo en empresas manufactureras y de servicios no públicos. A partir de las incidencias anuales se estimó en cada CCAA el porcentaje de cambio anual y su intervalo de confianza al 95% (IC95%) para e…

lcsh:Public aspects of medicineEstudios de evaluaciónlcsh:RAccidentes de trabajoPolíticas públicaslcsh:Medicinelcsh:RA1-1270Salud laboralGeneral Medicine
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Risk of Periodontal Disease: Is there a Correlation with the Type of Antihypertensive Medication?

2011

Introduction: The purpose of this study was to evaluate the effects of long-term oral antihypertensive treatment using centrally acting sympatho-inhibitory drugs (clonidine) and beta-blockers (metoprolol) on capillary microcirculation in the labial and periodontal mucosa.
 Methods: Sixty subjects were recruited for the study: 20 patients affected by hypertension in treatment with centrally-acting sympatho-inhibitory drugs (64.28 ± 11.78 years); 20 patients in treatment with beta-blockers (62.03 ± 9.84 years) and 20 healthy subjects (62.06 ± 6.72 years). We use the videocapillaroscopic technique to evaluate in vivo the microcirculation of the labial mucosa corresponding to the lower lip…

lcsh:R5-920medicine.medical_specialtymedicine.drug_classbusiness.industryGeneral MedicineGastroenterologyMicrocirculationSurgeryClonidinestomatognathic diseasesPharmacotherapyBlood pressureOral administrationSettore MED/28 - Malattie OdontostomatologicheInternal medicinemedicineHypertension antihypertensive drug oral videocapillaroscopyLabial Mucosalcsh:Medicine (General)Antihypertensive drugbusinessMetoprololmedicine.drug
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Salud laboral desde los servicios de la administración sanitaria: las oportunidades de la “perspectiva laboral” para el ejercicio de la salud pública

2020

La interacción entre salud pública y salud laboral desde los correspondientes servicios de la administración sanitaria sigue un abordaje que se podría formular en los siguientes términos: ¿qué puede hacer la salud pública por el mejor ejercicio la salud laboral?. Así, en salud laboral se trasladan a la atención sobre la población trabajadora conceptos y herramientas propios de la salud pública tales como los sistemas de vigilancia de enfermedades o los programas de promoción de la salud que, pese a las mutilaciones que impone “la puerta de la fábrica”, contribuyen a proteger y mejorar la salud de la población trabajadora. También se apuntan con enorme potencial (y no pocas dificultades) pro…

lcsh:RC963-969salud públicasalud comunitarialcsh:Industrial medicine. Industrial hygienesalud laboralvigilancia de brotesGeneral MedicineArchivos de Prevención de Riesgos Laborales
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Recycling of almond by-products for intestinal inflammation: improvement of physical-chemical, technological and biological characteristics of a drie…

2020

Background: Almond skins are rich in bioactive compounds that undergo oxidation/degradation phenomena and are poorly soluble in water, reducing in vivo absorption and bioavailability, factors that influence the pharmacological activity of an active product. We developed a dried acetonic almond skins extract/cyclodextrin complex to improve extract solubility, dissolution rate and biological activity. Methods: A lyophilized acetonic almond skin extract was produced. To optimize complex formulation, phase solubility studies and complex characterization (absorption studies, differential scanning calorimetry (DSC), morphology, solubility studies) were performed. To evaluate a possible use in hea…

lcsh:RS1-441Pharmaceutical ScienceAbsorption (skin)Articlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDifferential scanning calorimetrycatechinAlmond extractoxidative stressSolubilityDissolutionsolubility studies030304 developmental biologychemistry.chemical_classification0303 health sciencesChromatographyCyclodextrinfood and beveragesCatechinBiological activitycomplex characterizationBioavailabilityAlmond extract; cyclodextrin; catechin; solubility studies; complex characterization; intestinal epithelial cells; inflammation; oxidative stresschemistrycyclodextrininflammation030220 oncology & carcinogenesisintestinal epithelial cells
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Why the share of small amount pensions is so substantial in Latvia?

2018

More than 70% of all old-age pensions in Latvia are smaller than 300 euro, which is close to the monetary value of the at-risk-of-poverty threshold. There is a number of reasons for it: the lack of non-contributory component and inadequately low minimum pensions, the absence of redistribution mechanisms in the mandatory notional defined contribution (pillar I) and funded (pillar II) schemes, an unfair conversion of pre-reform employment record into pension formula, and a high tax burden on pensioners. The authors proposed a package of measures to improve the situation: an introduction of basis pensions, linking minimum pensions to the country average wages, increasing income tax exempt for …

lcsh:Social Scienceslcsh:HPensionLabour economicsMonetary valueIncome taxCapital (economics)PillarEconomicsRedistribution (cultural anthropology)Notional amountIndexationSHS Web of Conferences
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