Search results for "LAB"
showing 10 items of 7932 documents
Stability and bioaccessibility of EGCG within edible micro-hydrogels. Chitosan vs. gelatin, a comparative study
2016
Micro-hydrogels are very promising systems for the protection and controlled delivery of sensitive bioactives, but limited knowledge exists regarding the impact of this encapsulation on their bioaccessibility. In this work, two different hydrogel-forming biopolymers (gelatin and chitosan) were compared as wall materials for the microencapsulation of a model flavonoid, (−)-epigallocatechin gallate (EGCG). Results showed that gelatin was more adequate as wall material for the encapsulation of EGCG than chitosan, achieving higher encapsulation efficiencies (95% ± 6%), being more effective in delaying EGCG release and degradation in aqueous solution and exhibiting a 7 times higher bioaccessibil…
In vitro digestion of betalainic foods. Stability and bioaccessibility of betaxanthins and betacyanins and antioxidative potential of food digesta.
2008
Betalains are considered to be bioactive dietary phytochemicals. The stability of betacyanins and betaxanthins from either fresh foods or manufactured products of cactus pear fruit ( Opuntia ficus indica L. Mill. cv. Gialla and Rossa) and red beet ( Beta vulgaris L. ssp. vulgaris) was assessed in a simulated oral, gastric, and small intestinal digestion and compared with the digestive stability of purified pigments. A minor loss of indicaxanthin, at the gastric-like environment only, and a decrease of vulgaxanthin I through all digestion steps were observed, which was not affected by food matrix. In contrast, food matrix prevented decay of betanin and isobetanin at the gastric-like environm…
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases.
2013
Resveratrol-a natural polyphenolic compound-was first discovered in the 1940s. Although initially used for cancer therapy, it has shown beneficial effects against most cardiovascular and cerebrovascular diseases. A large part of these effects are related to its antioxidant properties. Here we review: (a) the sources, the metabolism, and the bioavailability of resveratrol; (b) the ability of resveratrol to modulate redox signalling and to interact with multiple molecular targets of diverse intracellular pathways; (c) its protective effects against oxidative damage in cardio-cerebro-vascular districts and metabolic disorders such as diabetes; and (d) the evidence for its efficacy and toxicity…
Resveratrol and stroke: from chemistry to medicine.
2014
Stroke is one of the most common cardiovascular diseases and is known as a leading cause of death in the world. Despite to its high prevalence, there are limited effective therapeutic strategies for stroke till now. However, oxidative stress plays an important role in the pathogenesis of stroke and therefore, antioxidant therapy could be used as a new therapeutic strategy. Among the antioxidants, some natural compounds are very interesting due to their low adverse effects. Resveratrol (3, 5, 4'-trihydroxystilbene) is a natural polyphenolic antioxidant found in grape skin, grape products, and peanuts as well as in red wine. In recent years, much attention has been paid to resveratrol due to …
Indicaxanthin Dietetics: Past, Present, and Future
2015
The betalamic acid derivatives of betalain pigments (purple-red betacyanins and yellow betaxanthins) are dietary compounds occurring in a few plant foods including beets (Beta vulgaris) and cactus pears (Opuntia spp.). Belonging to betaxanthins, indicaxanthin is rich in yellow cactus pear (Opuntia ficus indica L., Mill). High dietary bioavailability of indicaxanthin in humans, as well as its physicochemical properties, radical-scavenging and antioxidant activities in various experimental models suggest this molecule as a promising nutraceutical agent and open perspectives for its applications. Life-long modulatory activity at the epigenetic level now appears as the new frontier to shed ligh…
Betanin inhibits the myeloperoxidase/nitrite-induced oxidation of human low-density lipoproteins
2007
Production of nitrogen dioxide by the activity of myeloperoxidase (MPO) in the presence of nitrite is now considered a key step in the pathophysiology of low-density lipoprotein (LDL) oxidation. This study shows that betanin, a phytochemical of the betalain class, inhibits the production of lipid hydroperoxides in human LDL submitted to a MPO/nitrite-induced oxidation. Kinetic measurements including time-course of particle oxidation and betanin consumption, either in the presence or in the absence of nitrite, suggest that the antioxidant effect is possibly the result of various actions. Betanin scavenges the initiator radical nitrogen dioxide and can also act as a lipoperoxyl radical-scaven…
Antibacterial PEGylated Solid Lipid Microparticles for Cosmeceutical Purpose: Formulation, Characterization, and Efficacy Evaluation
2020
The development of efficacious means of delivering antioxidant polyphenols from natural sources for the treatment of skin diseases is of great interest for many cosmetic and pharmaceutical companies. Resveratrol (RSV) and Limonene (LIM) have been shown to possess good anti-inflammatory and antibacterial properties against Staphylococcus aureus infections responsible for many skin disorders, such as acne vulgaris. In this study, solid lipid microparticles are designed as composite vehicles capable of encapsulating a high amount of trans-RSV and enhancing its absorption through the stratum corneum. A microparticulate system based on mixture of PEGylate lipids, long-chain alcohols and LIM is a…
Rocības maksimizācijas stratēģijas Latvijas mājsaimniecībās
2018
Darba pētnieciskā tēma ir Latvijas mājsaimniecību labklājības nodrošināšanas stratēģijas pastāvošajā ekonomiskajā un sociālajā sistēmā Latvijā. Darba mērķis ir Latvijas mājsaimniecību ekonomiskās uzvedības izpēte un tās sasaiste ar nodokļu un sociālā atbalsta sistēmu Latvijā. Pētījumā analizēta piecu Latvijas mājsaimniecību ekonomiskā uzvedība, izmantojot tādus antropoloģiskos konceptus kā mājsaimniecība un mājsaimniecības stratēģijas. Pētījums apkopo piecu Latvijas mājsaimniecību finanšu datus, iknedēļas aktivitāšu datus un intervijas ar šo mājsaimniecību locekļiem. Rezultāti norāda, ka vairumā pētīto gadījumu mājsaimniecības neplāno un kopīgi nepieņem lēmumus par ilgtermiņa stratēģijām, k…
Mežs – Cilvēks – Izcirtums: Ainavas pārmaiņu izpratne mežu izciršanas procesā
2015
Mežs ir Latvijas ainavas neatņemama sastāvdaļa, iztikas un labbūtības avots, tomēr intensīvās mežizstrādes process ainavā ir ieviesis straujas pārmaiņas. Maģistra darba “Mežs – Cilvēks – Izcirtums: Ainavas pārmaiņu izpratne mežu izciršanas procesā” mērķis ir noskaidrot kā mežistrādes process ietekmē iedzīvotāju izpratni par pārmaiņām meža ainavā un procesa ietekmi uz labbūtību. Pētījuma dati iegūti 11 intervijās ar Alūksnes, Apes, Gulbenes un Smiltenes novada iedzīvotājiem. Kā interviju metode tika izmantota daļēji strukturētas līdzdošanās intervijas. Iegūtie rezultāti liecina, ka meža telpa ir normatīvā diskursa, praktiskās meža izmantošanas un subjektīvas labsajūtas sadursmes telpa, kurā …
El análisis cuantitativo de trayectorias laborales. Un estado del arte
2022
La metodología cuantitativa aplicada al estudio de las trayectorias laborales ha experimentado un rápido auge que se ha extendido más allá del tradicional análisis de secuencias. El presente artículo es un estado del arte del desarrollo de nuevas técnicas estadísticas que pueden aplicarse o ya se aplican al estudio de trayectorias laborales. Además, incluimos sugerencias de software estadístico para la aplicación de cada una de las técnicas descritas. A lo largo de todo el texto, podrá observarse que la descripción de cada técnica se ha realizado desde un punto de vista conceptual, con el objetivo de llegar a un público amplio, que no necesite poseer una fuerte formación estadística. Es med…