Search results for "LCI"

showing 10 items of 2760 documents

Mezenhimālo stromas šūnu osteoģenēzes raksturojums uz amorfā kalcija fosfāta biomateriāla

2021

Mezenhimālās stromas šūnas ir plaši pētīts šūnu veids to potenciālo ārstniecisko efektu dēļ, no kuriem populārākie ir imūnmodulācija un audu reģenerācija. Bakalaura darbs bija fokusēts uz mezenhimālo stromas šūnu pielietojumu kaulaudu reģenerācijā un to biosaderību ar amorfo kalcija fosfātu, kas organismā atrodams kaula veidošanās sākumstadijā. Darba mērķis bija raksturot uz amorfā kalcija fosfāta biomateriāla audzētu mezenhimālo stromas šūnu osteoģenēzes potenciālu. Osteoģenēzes raksturošanai izmantoja osteokalcīna imūnfluorescento iezīmēšanu, savukārt, biosaderību analizēja ar kolorimetrisko CKK-8 analīzi. Rezultāti uzrādīja, ka mezenhimālas stromas šūnas ir spējīgas augt uz biomateriāla,…

osteokalcīnsosteoģenēzeamorfais kalcija fosfātsFarmācijamezenhimālās stromas šūnas
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OSTEOPOROSI NELL’ANZIANO: UPDATE SULLE TERAPIE FARMACOLOGICHE E NON FARMACOLOGICHE

2010

osteoporosi anziano vitamina d calcio bisfosfonati teriparatide ranelato di stronzioSettore MED/09 - Medicina Interna
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THERAPEUTIC OPTIONS IN OSTEOPOROSIS

2010

osteoporosis bisphosphonates calcium vitamin d teriparatide strontium ranelate
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Le calcificazioni pancreatiche sono specifiche nella diagnosi di pancreatite cronica? Studio con TC multidetettore.

2008

pancreas CT calcification
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La "comunità dolciana", oggi. "Tecnologia" e prospettive pedagogiche

2009

pedagogia communitas Danilo Dolci Pierre Lévy
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Ridefinire l'agire educativo nel rispetto delle tecnologie del nostro tempo. La presenza di Danilo Dolci nel XXI secolo

2010

pedagogia tecnologie Danilo Dolci Pierre Lévy pedagogia socialeSettore M-PED/01 - Pedagogia Generale E Sociale
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Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors

2012

Herein we report the synthesis of a set of constrained peptidomimetics endowed with an electrophilic vinyl ester warhead and structurally related to a previously identified lead compound, a potent and irreversible inhibitor of falcipain-2 (FP-2). FP-2 is the main hemoglobinase of the malaria parasite P. falciparum. The new compounds were evaluated for their inhibition against FP-2, and the results were rationalized on the basis of docking experiments. These studies underscore the pivotal role of both the ester function at the P1' site and the trifluoromethyl group of the P3 side chain in determining the correct orientation of the Michael acceptor warhead in the catalytic site, and as a cons…

peptidomimeticdMolecular modelPeptidomimeticStereochemistryPlasmodium falciparumVinyl esterBiochemistrycysteine proteasesfalcipain-2 inhibitorsAntimalarialschemistry.chemical_compoundCatalytic DomainDrug DiscoverySide chainHumansEnzyme InhibitorsMalaria FalciparumGeneral Pharmacology Toxicology and PharmaceuticsPharmacologyTrifluoromethylOrganic Chemistrydocking studiescysteine proteases; peptidomimeticd; docking studies; falcipain-2 inhibitorsMolecular Docking SimulationCysteine EndopeptidaseschemistryDocking (molecular)Michael reactionMolecular MedicinePeptidomimeticsLead compoundChemMedChem
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Rotator cuff calcific tendinopathy: from diagnosis to treatment

2018

Rotator cuff calcific tendinopathy (RCCT) is a very common condition caused by the presence of calcific deposits in the rotator cuff (RC) or in the subacromial-subdeltoid (SASD) bursa when calcification spreads around the tendons. The pathogenetic mechanism of RCCT is still unclear. It seems to be related to cell-mediated disease in which metaplastic transformation of tenocytes into chondrocytes induces calcification inside the tendon of the RC. RCCT is a frequent finding in the RC that may cause significant shoulder pain and disability. It can be easily diagnosed with imaging studies as conventional radiography (CR) or ultrasound (US). Conservative management of RCCT usually involves rest,…

percutaneous treatmentsExtracorporeal Shockwave TherapyArthroscopyRotator CuffUSTendinopathyCalcinosisHumansReviewcalcific tendinopathyConservative Treatmentcalcific tendinopathy rotator cuff US MRI percutaneous treatmentsMRIActa bio-medica : Atenei Parmensis
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Zn,Al hydrotalcites calcined at different temperature: Characterisation and photocatalytic activity for the degradation of 2-propanol in gas-solid re…

2009

photocatalysi2-propanolSettore CHIM/07 - Fondamenti Chimici Delle Tecnologiehydrotalcites
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Characterization of Erwinia gerundensis A4, an Almond-Derived Plant Growth-Promoting Endophyte

2021

The rapidly increasing global population and anthropogenic climate change have created intense pressure on agricultural systems to produce increasingly more food under steadily challenging environmental conditions. Simultaneously, industrial agriculture is negatively affecting natural and agricultural ecosystems because of intensive irrigation and fertilization to fully utilize the potential of high-yielding cultivars. Growth-promoting microbes that increase stress tolerance and crop yield could be a useful tool for helping mitigate these problems. We investigated if commercially grown almonds might be a resource for plant colonizing bacteria with growth promotional traits that could be use…

plant growth promotionMicrobiology (medical)siderophorebiologybusiness.industryIntensive farmingCrop yieldErwinia gerundensisfood and beveragesbiology.organism_classificationPrunus dulcisMicrobiologyEndophyteQR1-502CropNutrientAgronomyAgriculturespermidineArabidopsis thalianaCultivarendophytebusinessFrontiers in Microbiology
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