Search results for "LDOS"

Renin-Angiotensin System Blockade and Mortality in Patients With Hypertension and COVID-19 Infection

2020

To determine the effect renin-angiotensin system blockers on the outcome in patients with hypertension and concurrent COVID-19 infection, we searched PubMed, the Cochrane Library, and Google Scholar for relevant articles. Twelve studies with a total of 16,101 patients met the inclusion criteria. The mortality rate among the users of angiotensin converting enzyme inhibitors or angiotensin receptor blockers was 12.15% and in non-users it was 14.56% (risk ratio 0.70, 95% CI [0.53-0.91], P < 0.007). There was no difference in the risk of death between the use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers (risk ratio 1.09, 95% CI [0.90 -1.32]). We conclude tha…

Association of Aldosterone and Cortisol with Cardiovascular Risk Factors in Prehypertension Stage

2012

Background. The Pakistani population has higher incidence of cardiovascular (CV) diseases at younger ages, due to undiagnosed, uncontrolled hypertension (HTN). A variety of associated HTN stressors is also reported. The study plans to understand the variables associated with initiation of HTN in this population.Objective. To find plasma aldosterone and cortisol relationship with some CV risk factors (obesity, dyslipidemia, hyperglycemia, sodium and potassium) in different stages of HTN particularly prehypertension.Subjects and Methods. The study conducted on 276 subjects (25–60 years), classified into prehypertensive (n=55), HTN stage-1 (n=70) and II (n=76) according to 7th JNC report and c…

Genetic variants of ANP and cardiometabolic protection: from populations to novel therapeutics

2013

Background The cardiac hormone atrial natriuretic peptide (ANP) induces natriuresis, vasodilation and inhibits aldosterone through the activation of the guanylyl cyclase A receptor (GC-A) and the second messenger cGMP. ANP possesses also metabolic properties enhancing lipolysis and release of the adipokine adiponectin. Previous studies in general populations reported that the minor G allele of the ANP genetic variant rs5068 is associated with increased circulating levels of ANP and B-type natriuretic peptide, lower blood pressure (BP), and reduced risk of hypertension. We recently reported that in the general population from Olmsted County, MN, USA the G allele of rs5068 is associated not o…

Hypokalemic rhabdomyolysis associated with Bartter's syndrome.

1983

Severe potassium deficiency is an uncommon cause of rhabdomyolysis. We recently treated a 45-year-old patient with myalgia, serious generalized weakness, increased serum creatine kinase and myoglobin level as well as excessive hypokalemia. Histological examination of deltoid muscle biopsy showed rhabdomyolysis. After complete recovery of muscle damage by potassium substitution Bartter's syndrome proved to be the cause of initial and persistent hypokalemia.

Relationship between obesity and plasma aldosterone in essential hypertension: influence of gender

2009

RELATIONSHIPS OF SERUM URIC ACID WITH PLASMA RENIN ACTIVITY AND PLASMA ALDOSTERONE IN PRIMARY HYPERTENSION.

2013

Introduction: In experimental studies conducted in rats, raising serum uric acid (SUA) levels resulted in stimulation of renin expression. Studies in humans exploring the association of SUA with plasma renin activity (PRA) yielded conflicting results. Moreover, little is known about the relationship between plasma aldosterone concentration (PAC) and SUA. Aim: To analyse the relationships between SUA, PRA and PAC in a group of subjects with primary hypertension. Methods: We enrolled 372 patients (mean age 45 ± 12 years; women 33 %), with untreated primary hypertension, with normal renal function and without cardiovascular complications. Results: Spearman’s rank-correlation analyses showed th…

Los Sistemas Productivos, el Aprendizaje Interno y los Resultados del Área de Producción de Baldosas-Cerámicas

2009

El objetivo de la investigacion es comprobar la validez del modelo universal de gestion en la estrategia de produccion en el sector de fabricantes de pavimentos y baldosas ceramicas espanoles. El trabajo se centra en las decisiones de infraestructura, y pretende resaltar el efecto de los recursos internos y externos sobre la ventaja competitiva del area de produccion de las empresas. Los datos utilizados corresponden a 76 empresas espanolas fabricantes de pavimentos ceramicos. Los resultados obtenidos permiten comprobar que en este sector los recursos implantados guardan poca relacion con las prioridades manifestadas. Ademas, se demuestra que la ventaja competitiva esta mas explicada por el…

Housing estates in the Baltic countries: the legacy of central planning in Estonia, Latvia and Lithuania

2019

Nuo 1960 iki 1990 metų Europos gyventojų skaičius nuolat augo, todėl buvo pradėta masinė daugiabučių statyba. Daugiabučiai gyvenamieji namai sudaro reikšmingą bendrojo būsto fondo dalį Vidurio ir Rytų Europoje. Trijose Baltijos šalių sostinėse – Vilniuje, Rygoje ir Taline – 2011 metų duomenimis 58–75% gyventojų buvo įsikūrę dideliuose daugiabučių kvartaluose. Knygos tikslas – pateikti išsamią daugiabučių paveldo apžvalgą. Straipsnių rinkinyje didelis dėmesys skiriamas tokio būsto tipo susiformavimui, iššūkiams ir ateities perspektyvoms. Knyga pateikia naują šios specifines statinių rūšies tipologiją, susijusią su sovietmečio palikimo kompleksiškumu. Įžangoje apžvelgiamos pagrindinės šešiose…