6533b838fe1ef96bd12a52f4

RESEARCH PRODUCT

Hypokalemic rhabdomyolysis associated with Bartter's syndrome.

J. MajdandzicJ BohlH J GöldnerH. Bierbach

subject

myalgiaMalemedicine.medical_specialtyendocrine system diseasesHypokalemiaurologic and male genital diseasesGastroenterologyNecrosisInternal medicineDeltoid muscleDrug DiscoveryBiopsyHyperaldosteronismmedicineHumansCreatine KinaseGenetics (clinical)Histological examinationmedicine.diagnostic_testbusiness.industryMyoglobinMusclesMyoglobinuriaBartter SyndromeGeneral MedicineMiddle Agedmedicine.diseaseHypokalemiaBartter's syndromeAnesthesiaPotassiumMolecular MedicinePotassium deficiencymedicine.symptombusinessRhabdomyolysis

description

Severe potassium deficiency is an uncommon cause of rhabdomyolysis. We recently treated a 45-year-old patient with myalgia, serious generalized weakness, increased serum creatine kinase and myoglobin level as well as excessive hypokalemia. Histological examination of deltoid muscle biopsy showed rhabdomyolysis. After complete recovery of muscle damage by potassium substitution Bartter's syndrome proved to be the cause of initial and persistent hypokalemia.

10.1007/bf01488972https://pubmed.ncbi.nlm.nih.gov/6843044