Search results for "LECTIN"
showing 10 items of 495 documents
The implication of MBL deficient haplotypes in acute coronary syndrome
2014
Le opere esposte da Maria Accascina alla Mostra d’Arte Sacra delle Madonie
2017
Il saggio espone i metodi e gli strumenti di ricerca utilizzati per la ricostruzione del catalogo della pioneristica Mostra D’Arte Sacra delle Madonie curata da Maria Accascina ed allestita nel 1937 presso il Convento dei PP. Riformati di Petralia Sottana, centro delle alte Madonie. Si tratta di più di quattrocento opere, tra gioielli, suppellettili liturgiche, oggetti preziosi di uso profano, coralli, paramenti sacri, tessuti, statue lignee, intagli, maioliche, tappeti, tele e tavole dipinte realizzate dal XI al XIX secolo. Le opere, alcune delle quali perdute, provengono dalle collezioni nobiliari, dall’allora Museo Nazionale di Palermo, ora Galleria Regionale della Sicilia, Palazzo Abate…
Effets de quartier, effet de département : discrimination liée au lieu de résidence et accès à l'emploi
2013
L’objet de cette étude est de mesurer la discrimination à l’embauche à l’encontre des jeunes en Ile-de-France en raison du lieu de résidence en considérant plusieurs échelles spatiales de façon à distinguer l’effet de la réputation du département (Paris et la Seine-Saint-Denis), celui de la localité et celui du quartier. L’évaluation est réalisée sur données expérimentales auto-construites de testing selon un protocole permettant d’examiner les effets propres à chacune de ces trois échelles sur l’accès à l’emploi ainsi que leurs effets cumulés. On s’intéresse aux discriminations pour deux professions en tension du secteur de la restauration pour laquelle les discriminations devraient a prio…
F-Type Lectins: A highly diversified family of fucose-binding proteins with a unique sequence motif and structural fold, involved in self/non-self-re…
2017
The F-type lectin (FTL) family is one of the most recent to be identified and structurally characterized. Members of the FTL family are characterized by a fucose recognition domain [F-type lectin domain (FTLD)] that displays a novel jellyroll fold (“F-type” fold) and unique carbohydrate- and calcium-binding sequence motifs. This novel lectin family comprises widely distributed proteins exhibiting single, double, or greater multiples of the FTLD, either tandemly arrayed or combined with other structurally and functionally distinct domains, yielding lectin subunits of pleiotropic properties even within a single species. Furthermore, the extraordinary variability of FTL sequences (isoforms) th…
Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on B…
2020
Copyright © 2020 Murugaiah, Agostinis, Varghese, Belmonte, Vieni, Alaql, Alrokayan, Khan, Kaur, Roberts, Madan, Bulla and Kishore. Human surfactant protein D (SP-D) belongs to the family of collectins that is composed of a characteristic amino-terminal collagenous region and a carboxy-terminal C-type lectin domain. Being present at the mucosal surfaces, SP-D acts as is a potent innate immune molecule and offers protection against non-self and altered self-such as pathogens, allergens, and tumour. Here, we examined the effect of a recombinant fragment of human SP-D (rfhSP-D) on a range of breast cancer lines. Breast cancer has four molecular subtypes characterised by varied expression of oes…
Immunological Markers for PML Prediction in MS Patients Treated with Natalizumab
2015
International audience; Natalizumab (NTZ), a monoclonal antibody recognizing the alpha4 integrin chain, has been approved for the treatment of active multiple sclerosis, but expose to the onset of a rare side effect, progressive multifocal leukoencephalopathy (PML). Estimating the individual risk of PML in NTZ-treated patients is a major challenge, and therapeutic strategies are mainly guided by the overall PML risk assessed by identified risk factors: JC virus (JCV) seropositivity, treatment duration (with peak incidence after 24 months), and the previous use of immunosuppressive therapies. Given that this stratification does not yet allow a precise individual prediction of PML, other pred…
Virtual Hierapolis: tra tecnicismo e realismo
2011
[ES] Una de las principales actividades de la MAIER tiene como objetivo desarrollar una línea de investigación dirigida a la restauración virtual y la reproducción 3D de los antiguos monumentos de la ciudad romana de Hierápolis de Frigia, Turquía. El proyecto, llamado "Virtual Hierápolis, se ha desarrollado gradualmente en las últimas tres temporadas de excavación (años 2007-2009) y ha madurado a partir de las primeras experiencias de la RV aplicada a este sitio en años anteriores. Esta investigación, coordinada por el Director de la misión italiana, prof. F. D'Andria, y llevada a cabo en el Laboratorio de Tecnologías de la Información (ITLab) dell'IBAM-CNR de Lecce (Italia), implica unidad…
Primary structure and opsonic activity of an F-lectin from serum of the gilt head bream Sparus aurata (Pisces, Sparidae)
2012
DIVERSITY OF LECTIN-SUGAR RECOGNITION SYSTEMS IN THE EVOLUTION OF FISH INNATE IMMUNITY
2014
Carbohydrate recognition and interactions mediated by lectins have been recognized involved in vertebrate innate immunity, not only for recognition of potential pathogens, but also acting in the agglutination, immobilization and other functional steps. Fish are equipped with a complex lectin repertoire that, like mammals, are involved almost all the immune reactions. On the basis of our results on the isolation, cDNA cloning, structural analysis, tissue expression and localization, and opsonic activity of F-type and RBL lectins from Dicentrarchus labrax and Sparus aurata we showed that: lectin repertoires in fish are highly diversified and include not only representatives of the lectin fami…