Search results for "LED"
showing 10 items of 8768 documents
Doubled haploid production in fruit crops
2006
The interest of fruit breeders in haploids and doubled haploids (DH), lies in the possibility of shortening the time needed to produce homozygous lines compared to conventional breeding. Haplo-diploidization through gametic embryogenesis allows single-step development of complete homozygous lines from heterozygous parents. In a conventional breeding programme, a pure line is developed after several generations of selfing. With fruit crops, characterized by a long reproductive cycle, a high degree of heterozygosity, large size, and, sometimes, self-incompatibility, there is no way to obtain haploidization through conventional methods. This paper reviews the current status of research on doub…
Using Dynamic Stories to Communicate Security and Safety Issues
2008
System dynamics (SD) models contain valuable insights on complex organizational issues that develop over time. However, for non-experts such models can be complex and difficult to understand. We propose Dynamic Stories, a methodology that uses storytelling, to rephrase expert terminology in simpler to understand action terms, thus overcoming knowledge transfer problems. To show the feasibility of the approach, we present our methodological framework.
Design for social media engagement: Insights from elderly care assistance
2015
Abstract This paper explores an alternative view of design as an emergent process of engagement and learning, as opposed to the traditional view of systems design as a problem-solving tool. We focus on digitally enabled elderly support networks as an innovative approach to the design of elderly care assistance through social media. Our research project is conducted in the context of an Italian health-care institution and provides the empirical backdrop illustrating the ensemble artefact, the four design principles and the pragmatic outcomes of personalized elderly care interventions. These contributions add both practical and theoretical guidance and learning regarding social-media engageme…
Knowledge Discovery from Network Logs
2015
Modern communications networks are complex systems, which facilitates malicious behavior. Dynamic web services are vulnerable to unknown intrusions, but traditional cyber security measures are based on fingerprinting. Anomaly detection differs from fingerprinting in that it finds events that differ from the baseline traffic. The anomaly detection methodology can be modelled with the knowledge discovery process. Knowledge discovery is a high-level term for the whole process of deriving actionable knowledge from databases. This article presents the theory behind this approach, and showcases research that has produced network log analysis tools and methods. peerReviewed
Competitive intelligence embeddedness: Drivers and performance consequences
2019
Abstract The proliferation of Web-based information sources and social media draw firms' attention to these channels as sources of competitive intelligence (CI). To date, research has focused mainly on information collection techniques rather than on CI uses and its influence on firm performance. We define CI embeddedness as the extent to which management and employees incorporate CI in daily routines, so that actionable knowledge is transferred throughout the organization. A survey of 124 decision makers reveals positive impact of Web CI sources as well as alliances with information providers on CI embeddedness. Furthermore, while CI embeddedness shows no direct influence on firms’ perform…
Application of LA-ICP-MS as a rapid tool for analysis of elemental impurities in active pharmaceutical ingredients.
2014
The control of inorganic contaminants in active pharmaceutical ingredients has a significant role in the quality control of drug products. The concentration limits for metal residues in drug products have been defined by various regulatory guidelines. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a powerful and fast analytical technique for multi-elemental analysis. A disadvantage in using LA-ICP-MS method is the lack of matrix reference materials for validation and calibration purposes. This article focuses on the handling strategy of laboratory-made matrix calibration standards for the quantification of elemental impurities in an active pharmaceutical ingredie…
A new approach to ticagrelor-based de-escalation of antiplatelet therapy after acute coronary syndrome. A rationale for a randomized, double-blind, p…
2021
The risk of ischemic events gradually decreases after acute coronary syndrome (ACS), reaching a stable level after 1 month, while the risk of bleeding remains steady during the whole period of dual antiplatelet treatment (DAPT). Several de-escalation strategies of antiplatelet treatment aiming to enhance safety of DAPT without depriving it of its efficacy have been evaluated so far. We hypothesized that reduction of the ticagrelor maintenance dose 1 month after ACS and its continuation until 12 months after ACS may improve adherence to antiplatelet treatment due to better tolerability compared with the standard dose of ticagrelor. Moreover, improved safety of treatment and preserved anti-is…
Intelligent Adaptive Motion Control for Ground Wheeled Vehicles
2014
In this paper a new intelligent adaptive control is applied to solve a problem of motion control of ground vehicles with two independent wheels actuated by a differential drive. The major objective of this work is to obtain a motion control system by using a new fuzzy inference mechanism where the Lyapunov’s stability can be assured. In particular the parameters of the kinematical control law are obtained using an intelligent Fuzzy mechanism, where the properties of the Fuzzy maps have been established to have the stability above. Due to the nonlinear map of the intelligent fuzzy inference mechanism (i.e. fuzzy rules and value of the rule), the parameters above are not constant, but, time a…
High definition colonoscopy combined with i-Scan is superior in the detection of colorectal neoplasias compared with standard video colonoscopy: a pr…
2010
Introduction Colonoscopy is the accepted gold standard for the detection of colorectal cancer. The aim of the current study was to prospectively compare high definition plus (HD+) colonoscopy with I-Scan functionality (electronic staining) vs. standard video colonoscopy. The primary endpoint was the detection of patients having colon cancer or at least one adenoma. Methods A total of 220 patients due to undergo screening colonoscopy, postpolypectomy surveillance or with a positive occult blood test were randomized in a 1 : 1 ratio to undergo HD+ colonoscopy in conjunction with I-Scan surface enhancement (90i series, Pentax, Tokyo, Japan) or standard video colonoscopy (EC-3870FZK, Pentax). D…
Faecal immunochemical tests: A valuable tool for colorectal cancer screening
2012
Colorectal cancer is a major health problem in industrialized ountries and fulfils the conditions required to justifymass screenng of the general population. Population-based controlled studies erformed in Europe have shown that guaiac faecal occult blood esting (G-FOBT) followed by colonoscopy to detect the cause of leeding can reduce colorectal cancer mortality [1]. Nearly all pubished studies evaluated the Hemoccult II (Beckman Coulter Inc., ea, USA) faecal occult blood test. Screening for colorectal caner using FOBT has, therefore, been included in the European Code gainst Cancer and has been endorsed by the European Commision [2]. Despite its high specificity, Hemoccult has been critic…