Search results for "LIES"

showing 10 items of 1093 documents

Clinical microbeam radiation therapy with a compact source: specifications of the line-focus X-ray tube

2020

Highlights • Line-focus X-ray tubes are suitable for clinical microbeam radiation therapy (MRT). • A modular high-voltage supply safely enables high electron beam powers. • An electron accelerator was designed to generate an eccentric focal spot. • We simulated a peak-to-valley dose ratio above 20 for single-field MRT. • Microbeam arc therapy spares healthy brain tissue compared to single-field MRT.

Equivalent uniform doselcsh:Medical physics. Medical radiology. Nuclear medicineMaterials scienceCompact radiation sourcelcsh:R895-920Monte Carlo methodElectronlcsh:RC254-282030218 nuclear medicine & medical imaginglaw.inventionCompact Radiation Source ; Equivalent Uniform Dose ; Line-focus X-ray Tube ; Microbeam Arc Therapy ; Microbeam Radiation Therapy ; Modular High-voltage Supply03 medical and health sciences0302 clinical medicineOpticslawRadiology Nuclear Medicine and imagingFocal Spot SizeOriginal Research ArticleLine-focus X-ray tubeRange (particle radiation)Radiationbusiness.industryMicrobeam arc therapyMicrobeamHot cathodeModular high-voltage supplyX-ray tubeequipment and supplieslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens030220 oncology & carcinogenesisCathode raybusinessMicrobeam radiation therapyPhysics and Imaging in Radiation Oncology
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Molecular and patho-physiological basis of syndromes with developmental anomalies and intellectual disability

2013

Intellectual disability (ID) corresponds to abnormal intellectual performances and adaptive functions, beginning in childhood. It is estimated that 2-3% of individuals develop a ID, which represents a significant medical challenge since people with ID are frequently in situations of social dependence. Overall, a critical involvement of genetic factors in this disease is suspected. To date, several hundreds of genes are known to be responsible for ID. The ID is particularly characterized by extreme clinical and genetic heterogeneity, that made it resistant to conventional genetic studies. However, it is classicaly separated between syndromic ID, which may be clinically recognizable due to as…

Exome sequencingMendelian disorders[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyShprintzen-Goldberg syndromeIntellectual disabilitySyndromes microdélétionnels[SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human geneticsAnomalies du développementDéficience intellectuelleSéquençage d’exomeMicrodeletionnal syndromesSyndrome de Shprintzen-Goldberg[SDV.BDD] Life Sciences [q-bio]/Development BiologyMultiple congenital anomalies[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyMaladies mendéliennes
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Surfactant-assisted synthesis of titanium nanoMOFs for thin film fabrication

2021

We use dodecanoic acid as a modulator to yield titanium MOF nanoparticles with good control of size and colloid stability and minimum impact to the properties of the framework to enable direct fabrication of crystalline, porous thin films. ispartof: CHEMICAL COMMUNICATIONS vol:57 issue:72 pages:9040-9043 ispartof: location:England status: published

FabricationYield (engineering)Materials scienceChemistry MultidisciplinaryNanoparticlechemistry.chemical_elementGood control02 engineering and technology010402 general chemistry01 natural sciencesCatalysisMETAL-ORGANIC FRAMEWORKSColloidPulmonary surfactantMaterials ChemistryThin filmScience & Technologytechnology industry and agricultureMetals and AlloysGeneral Chemistryequipment and supplies021001 nanoscience & nanotechnologyeye diseases0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsChemistrySIZEchemistryChemical engineeringPhysical SciencesACIDCeramics and CompositesNH2-MIL-125(TI)sense organs0210 nano-technologyTitaniumChemical Communications
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El tema de la diversidad sexual en la clase de ELE para niños: "El día de la rana roja"

2016

[EN] The family is the foundation and unifying force of children’s education. New family models have emerged in the last decades including single-parent, homosexual, and multicultural families. If this is an everyday reality, why not show it in the Spanish as a foreign language class through literature? We propose using picture books and the power of both images and words to teach children not only linguistic competence but also emotional intelligence. El día de la rana roja is chosen to illustrate how to teach Spanish as a foreign language through the story of two princes that is full of symbolism and readaptations of traditional topoi. It is an all-embracing, optimistic, and accepting sto…

Familias no tradicionalesEl día de la rana rojaELEIntercultural educationEducación interculturalLiteratura infantilSpanish as a foreing languageNon-traditional familiesChildren's literature
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Relaciones de parentesco en las nuevas familias: disociación entre maternidad/paternidad biológica, genética y social

2015

Se describen y analizan las relaciones de parentesco en las familias monoparentales, homoparentales, tardías o de edad avanzada, con embarazos múltiples, reconstituidas, adoptivas y las que recurren a las técnicas de reproducción asistida. En estas familias se puede producir una disociación entre relaciones conyugales y relaciones filiales; entre sexualidad y reproducción; entre pareja conyugal, pareja parental y pareja progenitora; y la creación de lazos de filiación independientemente de tener una relación de pareja. Asimismo, frente a la biparentalidad y heteroparentalidad, se pueden establecer relaciones de monoparentalidad, homoparentalidad, coparentalidad y pluriparentalidad. Estas fa…

Familias tardíasAdopciónAssisted reproductionHomo-parenthoodHomoparentalidadFamilias reconstituidasStepfamiliesReproducción asistidaSingle parenthoodAnthropologyAdoptionMonoparentalidadFamíliaSociologyHumanitiesOlder parenthoodGazeta de Antropología
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Famiglie, disagio e servizio sociale

2019

Il volume raccoglie contributi che intendono disvelare la natura sociale e culturale della famiglia. Gli autori dei contributi hanno messo in evidenza come la famiglia, lungi dall'essere una entità ovvia e data per scontata, sia invece il prodotto di aspettative, comportamenti socialmente strutturati, oltre che di negoziazioni e di rapporti di potere e dinamiche, talvolta profondamente conflittuali. The volume collects contributions that intend to reveal the social and cultural nature of the family.

Families hardship social work social change social relationships family relationships family dynamics transformations within the familySettore SPS/08 - Sociologia Dei Processi Culturali E ComunicativiFamiglie diasgio servizio sociale mutamento sociale relazioni sociali relazioni familiari dinamiche familiari trasformazioni in seno alla famiglia
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Family and teacher’s perception about the effects of Aprender a Convivir en Casa pilot program

2019

Several studies in the last decades provide scientific evidence about the benefits of family intervention at an early age. Carried out the implementation of the Aprender a Convivir en Casa [Learning to Live Together at Home] program (ACC), aimed for Spanish families with preschoolers to prevent behavioural problems, juvenile delinquency and harassment, as well as promote an optimal family functioning and parenting wellbeing; the aim of this study is to compare the effects on pre-schooler’s adaptive skills and behavioural problems through the BASC-P1 and BASC-T1, parents and teachers respectively. Parents of 18 three to five-year-old children participated in the study, 9 parents were assigne…

FamilieseducationConduct problemsSocial competencePrevention program
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Gene Regulation and Species-Specific Evolution of Free Flight Odor Tracking in Drosophila

2018

Running title: flight evolution in Drosophila This is an invited contribution to the special issue on Genetics of Adaptation based on a symposium of the same name at the National Centre for Biological Sciences (TIFR, Bangalore, India) in November 2016; International audience; The flying ability of insects has coevolved with the development of organs necessary to take-off from the ground, generate, and modulate lift during flight in complex environments. Flight orientation to the appropriate food source and mating partner depends on the perception and integration of multiple chemical signals. We used a wind tunnel-based assay to investigate the natural and molecular evolution of free flight …

Fatty Acid DesaturasesMale0301 basic medicineFat bodymelanogastercoordinationD. buzzatiiconsequencesReceptors OdorantPheromonesD. suzukiifliesDrosophila ProteinsGene Regulatory Networksfat bodyMatingRegulation of gene expressionbiologysex-pheromonesAnatomyBiological EvolutionoenocytemodulationDrosophilaFemaleFree flightZimbabweGenetic SpeciationsystemD. virilisEvolution Molecular03 medical and health sciencesSex FactorsSpecies Specificitydesaturase geneMolecular evolutiondesat1expressionGeneticsAnimalsMolecular BiologyDrosophilaGeneEcology Evolution Behavior and Systematics[SDV.GEN]Life Sciences [q-bio]/Geneticsfungibiology.organism_classification030104 developmental biologyGene Expression RegulationOdorEvolutionary biologyFlight Animalsexual dimorphismOdorants[ SDV.GEN ] Life Sciences [q-bio]/Genetics
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Characterization of Locally Excited and Charge-Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies

2020

[EN] Lapatinib (LAP) is an anticancer drug, which is metabolized to theN- and O-dealkylated products (N-LAP andO-LAP, respectively). In view of the photosensitizing potential of related drugs, a complete experimental and theoretical study has been performed on LAP,N-LAP andO-LAP, both in solution and upon complexation with human serum albumin (HSA). In organic solvents, coplanar locally excited (LE) emissive states are generated; they rapidly evolve towards twisted intramolecular charge-transfer (ICT) states. By contrast, within HSA only LE states are detected. Accordingly, femtosecond transient absorption reveals a very fast switching (ca. 2 ps) from LE (lambda(max)=550 nm) to ICT states (…

Femtosecond transient absorptionAntineoplastic AgentsSerum Albumin HumanMolecular Dynamics Simulation010402 general chemistryLapatinib01 natural sciencesAnticancer drugsCatalysisFluorescenceQUIMICA ORGANICAComputational chemistrymedicineHumansSpectroscopy010405 organic chemistryChemistryMolecular dynamics simulationsSpectrum AnalysisOrganic Chemistrydigestive oral and skin physiologyCharge (physics)LapatinibGeneral Chemistryequipment and suppliesAnticancer drug0104 chemical sciencesCharacterization (materials science)Excited stateUltrashort pulsehuman activitiesmedicine.drug
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Thermoosmotic transfer of sterically stabilized ferrofluid particles in non-isothermal capillary porous layer

2005

Experiments on thermodiffusive transfer of ferrofluid nanoparticles in capillary porous layer are presented. The layer consists of a number of capillary filter sheets pressed between two plates of different temperatures. Steady profiles of particle concentration are detected after the experiment from magnetization of each filter sheet. It is shown that particle separation in porous layer is remarkably influenced by thermoosmotic forces. The observed effect is different for colloids of various surfactants and of various carrier liquids.

FerrofluidMaterials scienceChemical engineeringCapillary actionParticleNanoparticleequipment and suppliesCondensed Matter PhysicsPorous mediumThermal diffusivityLayer (electronics)Isothermal processElectronic Optical and Magnetic MaterialsJournal of Magnetism and Magnetic Materials
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