Search results for "LIFETIME"

showing 10 items of 212 documents

A nitroreductase and glutathione responsive nanoplatform for integration of gene delivery and near-infrared fluorescence imaging

2020

A novel platform rationally integrating indocyanine green analogues and an arginine-rich dendritic peptide with both nitroreductase (NTR) and glutathione (GSH) reduction responsive linkers was developed. This multifunctional platform can enable selective and efficient gene delivery and specific turn-on fluorescence imaging in tumors.

Indocyanine GreenGlutathione metabolismFluorescence-lifetime imaging microscopyNear-Infrared Fluorescence ImagingInfrared RaysPeptideGene deliveryCatalysischemistry.chemical_compoundNitroreductaseOptical imagingMaterials ChemistryHumansFluorescent Dyeschemistry.chemical_classificationOptical ImagingGene Transfer TechniquesMetals and Alloysfood and beveragesGeneral ChemistryGlutathioneNitroreductasesGlutathioneSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryCeramics and CompositesBiophysicsPeptidesHeLa CellsChemical Communications
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Survey data and Bayesian analysis: a cost-efficient way to estimate customer equity

2014

We present a Bayesian framework for estimating the customer lifetime value (CLV) and the customer equity (CE) based on the purchasing behavior deducible from the market surveys on customer purchasing behavior. The proposed framework systematically addresses the challenges faced when the future value of customers is estimated based on survey data. The scarcity of the survey data and the sampling variance are countered by utilizing the prior information and quantifying the uncertainty of the CE and CLV estimates by posterior distributions. Furthermore, information on the purchase behavior of the customers of competitors available in the survey data is integrated to the framework. The introduc…

J.1FOS: Computer and information sciencesComputer sciencemedia_common.quotation_subjectEconomics Econometrics and Finance (miscellaneous)G.3Future valueCustomer relationship managementStatistics - ApplicationsScarcityFOS: Economics and businessEconometricscustomer equitysurveyApplications (stat.AP)media_commonMarketingbusiness.industry62N02 62-07 62F15Customer lifetime valueCompetitor analysisBayesian estimationPurchasingbrand switchingCustomer equitySurvey data collectioncustomer lifetime valueQuantitative Finance - General FinancebusinessGeneral Finance (q-fin.GN)G.3; J.1
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Josephson-based Threshold Detector for Lévy-Distributed Current Fluctuations

2019

We propose a threshold detector for Lévy-distributed fluctuations based on a Josephson junction. The Lévy-noise current added to a linearly ramped bias current results in clear changes in the distribution of switching currents out of the zero-voltage state of the junction. We observe that the analysis of the cumulative distribution function of the switching currents supplies information on both the characteristics' shape parameter α of the Lévy statistics. Moreover, we discuss a theoretical model, which allows characteristic features of the Lévy fluctuations to be extracted from a measured distribution of switching currents. In view of these results, this system can effectively find an appl…

Josephson effect---Current (mathematics)NOISE; FLIGHTS; FLUORESCENCE; LIFETIME; MODEL; STATE; FIELDGeneral Physics and Astronomy02 engineering and technologyLIFETIMEFault (power engineering)01 natural sciencesNoise (electronics)Settore FIS/03 - Fisica Della MateriaNOISE0103 physical sciencesStatistical physicsSuperconducting electronicsFLUORESCENCEFIELD010306 general physicsPhysicsResistive touchscreenDetectorFLIGHTSState (functional analysis)Josephson junctions Lévy processes non-thermal noise current fluctuations021001 nanoscience & nanotechnologySTATEMODEL0210 nano-technology
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Correlative atomic force and confocal fluorescence microscopy: single molecule imaging and force induced spectral shifts (Conference Presentation)

2016

A grand challenge in nanoscience is to correlate structure or morphology of individual nano-sized objects with their photo-physical properties. An early example have been measurements of the emission spectra and polarization of single semiconductor quantum dots as well as their crystallographic structure by a combination of confocal fluorescence microscopy and transmission electron microscopy.[1] Recently, the simultaneous use of confocal fluorescence and atomic force microscopy (AFM) has allowed for correlating the morphology/conformation of individual nanoparticle oligomers or molecules with their photo-physics.[2, 3] In particular, we have employed the tip of an AFM cantilever to apply c…

Kelvin probe force microscopeFluorescence-lifetime imaging microscopyMaterials sciencetechnology industry and agricultureNanotechnologySingle Molecule ImagingMolecular physicsFluorescence spectroscopylaw.inventionQuantum dotConfocal microscopylawMicroscopyPhotoconductive atomic force microscopyNanoimaging and Nanospectroscopy IV
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Conformational Transitions upon Maturation Rule Surface and pH-Responsiveness of α-Lactalbumin Microparticulates

2021

De novo designed protein supramolecular structures are nowadays attracting much interest as highly performing biomaterials. While a clear advantage is provided by the intrinsic biocompatibility and...

LactalbuminAmyloidFluorescence-lifetime imaging microscopyAmyloidBiocompatibilitySurface PropertiesChemistryBiochemistry (medical)Biomedical EngineeringSupramolecular chemistryBiocompatible MaterialspH-responsivenessGeneral ChemistryMicroparticlesHydrogen-Ion ConcentrationFluorescence Lifetime ImagingBiomaterialsMaturationMaterials TestingThioflavin TLactalbuminBiophysicsProtein CondensatesParticle SizeLiquid-Liquid Phase SeparationACS Applied Bio Materials
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Latvijas Universitātes Tautsaimniecības un tiesību zinātņu fakultātes tiesību zinātņu profesora Aleksandra Būmaņa kapakmenis Rīgas Meža kapos pēc atk…

1991

The tombstone of Alfrēds Būmanis, member of the Latvian Student fraternity Fraternitas Lettica, Latvian lawyer and professor of law at the Faculty of Economics and Law of the University of Latvia, at the Riga Forest Cemetery after the unveiling.

Latvijas Universitātes mācībspēkiLatvijas valsts neatkarības atjaunošanaStudent fraternitiesRestoration of the Latvian independenceStudentu korporācijasLaw science:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]Studentu akadēmiskās mūža organizācijasNational rememberenceNacionālā piemiņaTeaching staff of the University of LatviaTiesību zinātneStudent academical lifetime organisations
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Konstantīna Čakstes piemiņas plāksnes atklāšanas fotogrāfija

2023

Rakstā tiek skaidrota LU prof. Konstantīna Čakstes piemiņas tradīcijas uzsākšana LU, skaidrojot tā cēloņus (K. Čakstes kapavietas atklāšana), norisi (K. Čakstes piemiņas plāksnes atklāšana) un sekas (K. Čakstes piemiņas kopšana un tā labums LU Muzejam kā pētnieciskai atmiņu institūcija). Par raksta pamatu izvēlēta vēsturiska fotogrāfija, kurā attēlota K. Čakstes piemiņas plāksnes atklāšana, taču izmantots arī citu avotu un literatūras klāsts raksta sagatavošanā. Raksts sagatavots Latvijas valsts un LU 105 gadu jubileju ietvaros, kas mijas kopā ar pašreizējo starptautisko spriedzi - Krievijas-Ukrainas kara eskalāciju.

Latvijas Universitātes mācībspēkiPSRS sabrukumsLatvijas valsts neatkarības atjaunošanaRestoration of the Latvian independenceLatvijas UniversitāteStudentu akadēmiskās mūža organizācijasNational rememberenceThe University of LatviaCollapse of the USSRNational resistanceStudent academical lifetime organisationsNacionālā pretošanās:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]Nacionālā piemiņaTeaching staff of the University of Latvia
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1992. gada I semestra Latvijas Prezidiju konventa sēdes 25. protokols

1992

25th protocol of the 1992 1st semester session of the Presidium Convent reconstituted in Latvia, describing the renewal of student fraternities during the restoration of the Latvia's independence from the USSR, the Latvian student fraternity Fraternitas Lettica assuming the leadership of the Latvian Presidium Convent and its tasks during the quarter of the 1992 1st semester.

Latvijas valsts neatkarības atjaunošanaStudent fraternitiesRestoration of the Latvian independenceLatvijas Prezidiju KonventsLatvijas UniversitāteStudentu korporācijas:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]Studentu akadēmiskās mūža organizācijasPresidium Convent of LatviaStudentiThe University of LatviaStudent academical lifetime organisations
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1992. gada I semestra Latvijas Prezidiju konventa sēdes 26. protokols

1992

26th protocol of the 1992 1st semester Presidium Convent, describing the approval of 25th protocol, reports of officials, denationalisation of student fraternity property, organisation of the Latvian Union of Filister Societies and voting rights at meetings of the Presidium Convent.

Latvijas valsts neatkarības atjaunošanaStudent fraternitiesRestoration of the Latvian independenceStudent'sLatvijas Prezidiju KonventsLatvijas UniversitāteStudentu korporācijas:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]Studentu akadēmiskās mūža organizācijasPresidium Convent of LatviaStudentiThe University of LatviaStudent academical lifetime organisations
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Prevalence of Low Back Pain among Primary School Students from the City of Valencia (Spain)

2021

It is well-known that low back pain (LBP) prevalence is high among school-age children. However, literature concerning the initial onset of back pain between the ages of three and eleven years is scarce. The present study aims to analyze the prevalence of LBP in kindergarten and primary school students. A total of 278 (9.9 ± 2.1 years old

Leadership and ManagementeducationprevalenceLifetime prevalencelcsh:MedicineHealth InformaticsArticleKindergartenprimary school03 medical and health sciences0302 clinical medicineHealth Information Managementchildrenhealth services administrationPrevalenceBack painMedicineLow back painkindergarten030212 general & internal medicineChildrenlow back painPrimary schoolbusiness.industryHealth Policylcsh:Rback healthLow back painnervous system diseasesbody regionsExact testpopulation characteristicsmedicine.symptombusinessBack health030217 neurology & neurosurgeryDemographyHealthcare
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