Search results for "LIMIT"

showing 10 items of 2826 documents

Infrared based saliva screening test for COVID‐19

2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented need for diagnostic testing that is critical in controlling the spread of COVID-19. We propose a portable infrared spectrometer with purpose-built transflection accessory for rapid point-of-care detection of COVID-19 markers in saliva. Initially, purified virion particles were characterized with Raman spectroscopy, synchrotron infrared (IR) and AFM-IR. A data set comprising 171 transflection infrared spectra from 29 subjects testing positive for SARS-CoV-2 by RT-qPCR and 28 testing negative, was modeled using Monte Carlo Double Cross Validation with 50 randomized test and model sets. The testing se…

SalivaMaterials scienceCoronavirus disease 2019 (COVID-19)Spectrophotometry InfraredInfraredPoint-of-care testingInfrared spectroscopy010402 general chemistry01 natural sciencesProof of Concept StudySensitivity and SpecificityCatalysisSpecimen HandlingCohort Studies03 medical and health sciences0302 clinical medicineCOVID-19 TestingSpectrophotometryChlorocebus aethiopsmedicineCOVID-19 diagnostic infrared spectroscopy Raman spectroscopy saliva SARS-CoV-2 virionsAnimalsHumansQDLeast-Squares AnalysisSalivaVero CellsMass screening030304 developmental biologyDetection limit0303 health sciencessalivaChromatographymedicine.diagnostic_test010405 organic chemistrySARS-CoV-2COVID-19Discriminant AnalysisGeneral Chemistry030206 dentistryGeneral Medicine0104 chemical sciences3. Good healthPoint-of-Care TestingMonte Carlo MethodATR-FTIRResearch ArticleAngewandte Chemie (International Ed. in English)
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Determination of Third-Generation Synthetic Cannabinoids in Oral Fluids.

2020

Abstract A procedure has been developed for the determination of third-generation synthetic cannabinoids in oral fluid samples by using a semi-automated microextraction by packed sorbent (MEPS) procedure and gas chromatography–mass spectrometry (GC–MS) determination. Five synthetic cannabinoids were employed as model compounds 5F-ADB, MMB-CHMICA, THJ-2201, CUMYL-4CN-BINACA and MDMB-CHMCZCA. The most adequate operative conditions for MEPS were evaluated giving quantitative recoveries, from 89 to 124%, in synthetic and field saliva samples spiked with 125 and 250 μg/L of the studied cannabinoids, with the exception of MDMB-CHMCZCA in field saliva samples that provided slightly lower recoverie…

SalivaSorbentHealth Toxicology and MutagenesisToxicologyMass spectrometry01 natural sciencesGas Chromatography-Mass SpectrometryAnalytical Chemistry03 medical and health sciences0302 clinical medicineSynthetic cannabinoidsmedicineEnvironmental Chemistry030216 legal & forensic medicineSalivaDetection limitChemical Health and SafetyChromatographyChemistryCannabinoidsIllicit Drugs010401 analytical chemistryThird generation0104 chemical sciencesOral fluidGas chromatography–mass spectrometrymedicine.drugJournal of analytical toxicology
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Analysis of primary aliphatic short-chain monoamines by LC in water samples

2003

Abstract Several derivatization procedures with o-phthaldialdehyde-N-acetylcysteine (OPA-NAC) were compared for a rapid analysis of primary aliphatic short-chain monoamines in water samples by HPLC using a LiChorospher analytical separation column (100RP18 125 mm ×4  mm i.d., 5 μm). Both the solution and the solid-support assisted off-line derivatization on C18 SPE cartridges were inadequate options because of beginning degradation processes of the instable isoindol derivatives during their transfer to the analytical column. This problem was precluded with the on-column or solid-support assisted on-line derivatization. In the last mentioned procedure, the derivatization took place in a Hype…

Sample handlingDetection limitReaction ratechemistry.chemical_compoundCartridgeChromatographyChemistrySeparation columnSolid phase extractionDerivatizationHigh-performance liquid chromatographyAnalytical ChemistryTalanta
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Factors contributing to the variability in muscle ageing

2012

a b s t r a c t Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbing stairs. The rate of structural and functional deterioration of muscle appears to vary considerably between people. Part of the variation in the 'rate of muscle ageing' is attributable to genetic factors, the timing of changes in circulating hormones and the presence or absence of chronic low-grade systemic inflammation. Where an individual cannot change much i…

SarcopeniaWeaknessmedicine.medical_specialtyInflammationSystemic inflammationGeneral Biochemistry Genetics and Molecular BiologyMicrocirculationInternal medicineActivities of Daily LivingmedicineHumansMobility LimitationMuscle SkeletalExerciseWastingInflammationMuscle Weaknessbusiness.industryObstetrics and GynecologyMuscle weaknessHormonesCapillariesEndocrinologyAgeingmedicine.symptomEnergy IntakebusinessHormoneMaturitas
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"sbottom-tau exp" of "Search for bottom-squark pair production in $pp$ collision events at $\sqrt{s} = 13$ TeV with hadronically decaying $\tau$-lept…

2021

The expected exclusion contour at $95\%$ CL as a function of the M(Sbottom) vs. M(N2) with the $\Delta M$(N2,N1) = 130 GeV. Masses within the contour are excluded.

Sbottom13000.03rd GenerationObservedCLSP P --> SBOTTOM SBOTTOMSUSYSupersymmetryLimit
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"UpperLimit" of "Search for bottom-squark pair production in $pp$ collision events at $\sqrt{s} = 13$ TeV with hadronically decaying $\tau$-leptons, …

2021

Observed upper limits on the signal cross section as a function of the M(Sbottom) vs. M(N2) with the $\Delta M$(N2,N1) = 130 GeV.

Sbottom13000.0P P --> SBOTTOM SBOTTOM X3rd GenerationObservedCLSSUSYSupersymmetryLimit
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"UpperLimitExp" of "Search for bottom-squark pair production in $pp$ collision events at $\sqrt{s} = 13$ TeV with hadronically decaying $\tau$-lepton…

2021

Expected upper limits on the signal cross section as a function of the M(Sbottom) vs. M(N2) with the $\Delta M$(N2,N1) = 130 GeV.

Sbottom13000.0P P --> SBOTTOM SBOTTOM X3rd GenerationObservedCLSSUSYSupersymmetryLimit
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"sbottom-tau obs" of "Search for bottom-squark pair production in $pp$ collision events at $\sqrt{s} = 13$ TeV with hadronically decaying $\tau$-lept…

2021

The observed exclusion contour at $95\%$ CL as a function of the M(Sbottom) vs. M(N2) with the $\Delta M$(N2,N1) = 130 GeV. Masses within the contour are excluded.

Sbottom13000.0P P --> SBOTTOM SBOTTOM X3rd GenerationObservedCLSSUSYSupersymmetryLimit
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"Eff_MultiBin3" of "Search for bottom-squark pair production in $pp$ collision events at $\sqrt{s} = 13$ TeV with hadronically decaying $\tau$-lepton…

2021

Efficiency in the Multi-bin SR, $\min_{\Theta} > 1.0$ bin as a function of the M(Sbottom) vs. M(N2) with the $\Delta M$(N2,N1) = 130 GeV. Keep in mind that the efficiency is given in units of $10^{-2}$.

Sbottom13000.0P P --> SBOTTOM SBOTTOM X3rd GenerationObservedEFFSUSYSupersymmetryLimit
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"Eff_SingleBin" of "Search for bottom-squark pair production in $pp$ collision events at $\sqrt{s} = 13$ TeV with hadronically decaying $\tau$-lepton…

2021

Efficiency in the Single-bin SR as a function of the M(Sbottom) vs. M(N2) with the $\Delta$ M(N2,N1) $= 130$ GeV. Keep in mind that the efficiency is given in units of $10^{-2}$.

Sbottom13000.0P P --> SBOTTOM SBOTTOM X3rd GenerationObservedEFFSUSYSupersymmetryLimit
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