Search results for "LOCI"
showing 10 items of 1277 documents
Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation.
2014
Autism Spectrum Disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies have investigated the role of de novo Copy Number Variants (CNVs) and microRNAs as important but distinct etiological factors in ASD. We developed a novel computational procedure to assess the potential pathogenic role of microRNA genes overlapping de novo CNVs in ASD patients. Here we show that for chromosomes # 1, 2 and 22 the actual number of miRNA loci affected by de novo CNVs in patients was found significantly higher than that estimated by Monte Carlo simulation of random CNV events. Out of 24 miRNA genes over-represented in CNVs from these three chromosomes only …
Shapes and oscillations of raindrops with reduced surface tensions: Measurements at the Mainz vertical wind tunnel
2013
Abstract Important characteristics of raindrops pertinent to fields in atmospheric sciences such as weather radar or pollution scavenging are drop shape, oscillation frequency and amplitude, as well as the internal circulation. Atmospheric raindrops are never pure water drops but contain additional components like aerosol particles and dissolved species. Surface active substances, when present, reduce the surface tension of raindrops and, thus, increase the drop deformation which in turn affects breakup and coalescence, pollutant scavenging, and, finally, the formation of precipitation. Experiments were performed at the Mainz vertical wind tunnel with raindrops freely suspended at their ter…
ADCP velocity profiles analisys in the Castellammare gulf
2009
Velocity profiles have been collected in three points within the Castellammare gulf at around 1500 m far from the coastline. This area is characterized by the presence of an aquaculture farm that positioned 5 floating cages in this zone. The impact of this activity on the environment strictly depends on the currents and water exchange. The general aim of this research is the characterization of the circulation characteristics of this area. The analysis of the free surface oscillations shows the typical behaviour of tide forcing, with high minima and maxima during the night, due to the higher moon attraction during these hours compared with the morning hours. A prevalent current direction fr…
Genome-wide detection of signatures of selection in three Valdostana cattle populations
2020
International audience; The Valdostana is a local dual purpose cattle breed developed in Italy. Three populations are recognized within this breed, based on coat colour, production level, morphology and temperament: Valdostana Red Pied (VPR), Valdostana Black Pied (VPN) and Valdostana Chestnut (VCA). Here, we investigated putative genomic regions under selection among these three populations using the Bovine 50K SNP array by combining three different statistical methods based either on allele frequencies (F-ST) or extended haplotype homozygosity (iHS and Rsb). In total, 8, 5 and 8 chromosomes harbouring 13, 13 and 16 genomic regions potentially under selection were identified by at least tw…
The Coble Quadric
2023
Given a smooth genus three curve $C$, the moduli space of rank two stable vector bundles on C with trivial determinant embeds in $\mathbb{P}^8$ as a hypersurface whose singular locus is the Kummer threefold of $C$; this hypersurface is the Coble quartic. Gruson, Sam and Weyman realized that this quartic could be constructed from a general skew-symmetric fourform in eight variables. Using the lines contained in the quartic, we prove that a similar construction allows to recover SU$_C(2, L)$, the moduli space of rank two stable vector bundles on C with fixed determinant of odd degree L, as a subvariety of $G(2, 8)$. In fact, each point $p \in C$ defines a natural embedding of SU$_C(2, \mathca…
On the Second Order Rational Difference Equation $$x_{n+1}=\beta +\frac{1}{x_n x_{n-1}}$$ x n + 1 = β + 1 x n x n - 1
2016
The author investigates the local and global stability character, the periodic nature, and the boundedness of solutions of the second-order rational difference equation $$x_{n+1}=\beta +\frac{1}{x_{n}x_{n-1}}, \quad n=0,1,\ldots ,$$ with parameter \(\beta \) and with arbitrary initial conditions such that the denominator is always positive. The main goal of the paper is to confirm Conjecture 8.1 and to solve Open Problem 8.2 stated by A.M. Amleh, E. Camouzis and G. Ladas in On the Dynamics of a Rational Difference Equations I (International Journal of Difference Equations, Volume 3, Number 1, 2008, pp.1–35).
The Variation of the Fractional Maximal Function of a Radial Function
2017
Abstract In this article, we study the regularity of the non-centered fractional maximal operator $M_{\beta}$. As the main result, we prove that there exists $C(n,\beta)$ such that if $q=n/(n-\beta)$ and $f$ is radial function, then $\|DM_{\beta}f\|_{L^{q}({\mathbb{R}^n})}\leq C(n,\beta)\|Df\|_{L^{1}({\mathbb{R}^n})}$. The corresponding result was previously known only if $n=1$ or $\beta=0$. Our proofs are almost free from one-dimensional arguments. Therefore, we believe that the new approach may be very useful when trying to extend the result for all $f\in W^{1,1}({\mathbb{R}^n})$.
Gozosas matanzas
2002
Citocentrifugación como un método adicional para estudiar celomitos de equinodermos: un enfoque comparativo que combina células vivas, preparaciones …
2021
Abstract Introduction: Echinoderm coelomocytes have traditionally been investigated through a morphological approach using light microscopy, which relies on the idea of constant cell shape as a stable character. However, this can be affected by biotic or abiotic conditions. Objective: To analyze if the consistency in cell morphology offered by the cytocentrifugation method, might be used as a convenient tool to study echinoderm coelomocytes. Methods: Cells of Echinaster (Othilia) brasiliensis (Asteroidea), Holothuria (Holothuria) tubulosa (Holothuroidea), Eucidaris tribuloides, Arbacia lixula, Lytechinus variegatus, and Echinometra lucunter (Echinoidea) were spread on microscope slides by c…
Exploring parallel capabilities of an innovative numerical method for recovering image velocity vectors field
2010
In this paper an efficient method devoted to estimate the velocity vectors field is investigated. The method is based on a quasi-interpolant operator and involves a large amount of computation. The operations characterizing the computational scheme are ideal for parallel processing because they are local, regular and repetitive. Therefore, the spatial parallelism of the process is studied to rapidly proceed in the computation on distributed multiprocessor systems. The process has shown to be synchronous, with good task balancing and requiring a small amount of data transfer.