Search results for "LOCI"

Transcranial Doppler and Cortical Microcirculation at Increased Intracranial Pressure and during the Cushing Response

1995

The effect of increased intracranial pressure on the flow velocity of the basilar artery was measured with transcranial ultrasonic Doppler in New Zealand White rabbits under alpha-chloralose anesthesia and artificial respiration. Laser Doppler flowmetry served to study changes of the cortical microcirculation. The results confirm a high inverse correlation of the diastolic flow velocity, the pulsatility index, and the resistance index with the cerebral perfusion pressure (CPP). During acute intracranial hypertension, however, these parameters do not show a good correlation with the local cortical blood flow. The absence of a correlation was evident over a wide CPP range down to values of 35…

Update on topical carbonic anhydrase inhibitors

2001

Topical carbonic anhydrase inhibitors are a novel addition to the armamentarium of medical glaucoma treatment; dorzolamide has been available since 1995 and brinzolamide since 1998. They lower intraocular pressure by inhibiting carbonic anhydrase, a key enzyme for aqueous humor formation. Intraocular pressure-lowering activity of the substances appears to be the same and is similar to that of most other agents, but it does not reach the activity of the unselective beta-blocker timolol or the prostaglandin latanoprost. On concomitant treatment, additivity is reached with all other topical agents. A possible improvement of blood flow may offer an additional benefit, but its significance for t…

Does transvaginal color Doppler sonography differentiate between developing and involuting ectopic pregnancies?

1995

The objective of this study was to assess the addition of transvaginal color Doppler imaging to transvaginal ultrasonography and beta-human chorionic gonadotropin values to differentiate between developin and involuting ectopic pregnancies. Forty surgically confirmed ectopic pregnancies were classified into developing or involuting according to histopathologic findings. Results were compared retrospectively with the plasma beta-human chorionic gonadotropin values as well as the resistive index and pulsatility index obtained in corpora lutea and peritrophoblastic flow in serial examinations. Student's t-test was used for comparison of means. Logistic regression analysis was applied to predic…

Effect of pistachio on brachial artery diameter and flow-mediated dilatation: A systematic review and meta-analysis of randomized, controlled-feeding…

2017

Background: Results of previous clinical trials evaluating the effect of pistachio supplementation on endothelial reactivity (ER) are controversial. Aims: We aimed to assess the impact of pistachio on ER through systematic review of literature and meta-analysis of available randomized, controlled-feeding clinical studies (RCTs). Methods: The literature search included SCOPUS, PubMed-Medline, ISI Web of Science and Google Scholar databases up to 1st August 2017 to identify RCTs investigating the impact of pistachio on ER. Two independent reviewers extracted data on study characteristics, methods and outcomes. Overall, the impact of pistachio on ER was reported in 4 trials. Results: The meta-…

Active deformation in southern Italy from gnss velocities: updated results of the PTGA network

2010

Active deformation in Southern Italy, Sicily and southern Sardinia from GPS velocities of the Peri-Tyrrhenian Geodetic Array (PTGA)

2008

Campaign measurement (1995-2000) of Global Positioning System (GPS) site velocities in southern Italy, Central Mediterranean area, document differential displacements within the orogens rimming the Tyrrhenian Sea. Within the Southern Apennines, GPS velocities define two laterally juxtaposed belts of deformation, with transpression in the east and transtension in the west. In the east, ~8 mm/yr convergence between northern Murge-Gargano block and the International GPS System (IGS) site MATE is partitioned across ~east-west striking right-lateral faults, consistent with seismicity and with the offshore geological record. To the south, in northern Calabria, site velocities relative to MATE ind…

Audzināšanas ideāls un īstenība: raksti par lietišķu paidagoģiju

1928

Saturs: Ievadam 3 Par lietišķu un romantisku paidagoģiju 5 Audzinātāja jēdziens un būtība 25 Mūsu paidagoģiskā prakse Pestalocija mācību apgaismojumā 46 Paidagoģijā un politika 60 Audzināšanas zinātnes sākumi 83

Three-Dimensional Kinematics during the Take-Off Phase in Competitive Long Jumping

2013

The purpose of the present study was to identify the relationships among selected kinematic variables that affect the take-off phase and performance in elite jumpers. The jump distance was found to be related to: I) the athlete's approach speed before the instant of touch down; and ii) the exchange in spatial velocity components at take-off, which results in a gain in maximum vertical velocity of the centre of mass (CM), favoured by the use of an optimum touch-down angle of the take-off leg, an active landing of the foot at touch-down, and a motion of the take-off leg during the compression phase that helps to manage the loss of horizontal velocity. Nonetheless, the results show that an ad…

Localization in Structured Environments with UWB Devices without Acceleration Measurements, and Velocity Estimation Using a Kalman–Bucy Filter

2022

In this work, a novel scheme for velocity and position estimation in a UWB range-based localization system is proposed. The suggested estimation strategy allows to overcome two main problems typically encountered in the localization systems. The first one is that it can be suitable for use in environments where the GPS signal is not present or where it might fail. The second one is that no accelerometer measurements are needed for the localization task. Moreover, to deal with the velocity estimation problem, a suitable Kalman–Bucy filter is designed and it is compared, experimentally, with a particle filter by showing the features of the two algorithms in order to be used in a localization …

Genome-Wide Association Analysis in Primary Sclerosing Cholangitis

2010

Background & Aims We aimed to characterize the genetic susceptibility to primary sclerosing cholangitis (PSC) by means of a genome-wide association analysis of single nucleotide polymorphism (SNP) markers. Methods A total of 443,816 SNPs on the Affymetrix SNP Array 5.0 (Affymetrix, Santa Clara, CA) were genotyped in 285 Norwegian PSC patients and 298 healthy controls. Associations detected in this discovery panel were re-examined in independent case-control panels from Scandinavia (137 PSC cases and 368 controls), Belgium/The Netherlands (229 PSC cases and 735 controls), and Germany (400 cases and 1832 controls). Results The strongest associations were detected near HLA-B at chromosome 6p21…