Search results for "LONG"
showing 10 items of 3969 documents
A Hybrid Model for an E-learning System Which Develops Metacognitive Skills at Students
2013
One of the goals of academic education is to train students in view of acquiring metacognitive skills, thus becoming self-regulated learners prepared for for lifelong learning. The research in this area has proved that metacognition can be taught and learned and that self-regulation behavior can be guided and constrained by the features of the learning environment. In order to become an educational environment, attractive and at the same time efficient for the students and which would enable students to develop their metacognitive skills, the e-learning system needs continuous improvments. This paper presents a hybrid model of an e-learning system, MEM - Metacognitive E-learning system Mode…
Trends and cycles in U.S. job mobility
2021
Recent studies document a decline in U.S. labor-market fluidity from as early as the 1970s on. Making use of the Annual Social and Economic (ASEC) supplement to the Current Population Survey (CPS), I uncover a pronounced increase in job-to-job mobility from the 1970s to the 1990s, i.e., the annual share of continuously employed job-to-job movers rises from 5.9 percent of the labor force in 1975–1979 to 8.8 percent in 1995–1999. Job-to-job mobility exhibits a downward trend only since the turn of the millennium. In order to provide a formal economic interpretation, I additionally estimate the parameters of the random on-the-job search model. Furthermore, I document that job-to-job mobility h…
KNOWLEDGE MANAGEMENT AND POSSIBILITIES OF PROFESSIONAL DEVELOPMENT IN PUBLIC SECTOR
2014
One of the important parts of Human Resource Management (HRM) is knowledge management and professional development of employees of each organisation. There are no doubts that it is vital for general organisations development and sustainability. Professional development of public sector employees is necessary for developing environment. There should be training programmes especially for public sector institutions’ employees from new European Union countries. For this study authors make the assumption that public sector employees are all officials, civil servants, staff and employees engaged in public sector organisation activities and employed by these organisations. The problem outlined in …
Development and Long-Term Follow-Up of an Experimental Model of Myocardial Infarction in Rabbits
2020
Simple Summary Ischemic heart disease is one of the leading causes of death. A series of processes occur during acute myocardial infarction that contribute to the development of ventricular dysfunction, with subsequent heart failure and ventricular arrhythmias, which account for most episodes of sudden cardiac death in these patients. These complications are associated with the adverse cardiac remodeling that occurs during the healing process following an acute episode. The remodeling causes the appearance of a substrate that can trigger life-threatening arrhythmias, such as tachycardia and/or ventricular fibrillation. The development of experimental models for analyzing the basic mechanism…
Catalyzing transcriptomics research in cardiovascular disease: The CardioRNA COST action CA17129
2019
WOS: 000474931400001
Improved Assessment of Pathological Regurgitation in Patients with Prosthetic Heart Valves by Multiplane Transesophageal Echocardiography
1997
The aim of this study was to evaluate the diagnostic increment of individually optimized axes in the assessment of pathological prosthetic valve regurgitation. Forty-two patients with pathologically regurgitant prostheses in the aortic (n = 21), mitral (n = 15), and tricuspid (n = 6) positions were examined by multiplane transesophageal echocardiography. The investigation was performed utilizing the transverse axis first, the longitudinal axis second, and the intermediate axes afterwards. The presence of regurgitation, the differentiation between trans- and perivalvular origin, and the localization of perivalvular leakages at the sewing ring were evaluated. Findings in the biplane and inter…
Complementation of Saccharomyces cerevisiae mutationsin genes involved in translation and protein folding (EFB1 and SSB1)with Candida albicans cloned…
2000
We have demonstrated that the expression of Candida albicans genes involved in translation and protein folding (EFB1 and SSB1) complements the phenotype of Saccharomyces cerevisiae mutants. The elongation factor 1beta (EF-1beta) is essential for growth and efb1 S. cerevisiae null mutant cells are not viable; however, viable haploid cells, carrying the disrupted chromosomal allele of the S. cerevisiae EFB1 gene and pEFB1, were isolated upon sporulation of a diploid strain which was heterozygous at the EFB1 locus and transformed with pEFB1 (a pEMBLYe23 derivative plasmid containing an 8-kb DNA fragment from the C. albicans genome which contains the EFB1 gene). This indicates that the C. albic…
Investigation of protein folding by coarse-grained molecular dynamics with the UNRES force field.
2010
Coarse-grained molecular dynamics simulations offer a dramatic extension of the time-scale of simulations compared to all-atom approaches. In this article, we describe the use of the physics-based united-residue (UNRES) force field, developed in our laboratory, in protein-structure simulations. We demonstrate that this force field offers about a 4000-times extension of the simulation time scale; this feature arises both from averaging out the fast-moving degrees of freedom and reduction of the cost of energy and force calculations compared to all-atom approaches with explicit solvent. With massively parallel computers, microsecond folding simulation times of proteins containing about 1000 r…
Might exogenous circular RNAs act as protein-coding transcripts in plants?
2021
Circular RNAs (circRNAs) are regulatory molecules involved in the modulation of gene expression. Although originally assumed as non-coding RNAs, recent studies have evidenced that animal circRNAs can act as translatable transcripts. The study of plant-circRNAs is incipient, and no autonomous coding plant-circRNA has been described yet. Viroids are the smallest plant-pathogenic circRNAs known to date. Since their discovery 50 years ago, viroids have been considered valuable systems for the study of the structure-function relationships in RNA, essentially because they have not been shown to have coding capacity. We used two pathogenic circRNAs (Hop stunt viroid and Eggplant latent viroid) as …
Die Best�ndigkeit der Eiweissfraktionen und Fermente in lange gelagerten menschlichen Serumkonserven
1951
Die Untersuchung von 8 flussigen Serumkonserven, wie sie im Kriege als Blutersatzmittel verwendet und die 5–6 Jahre bei Zimmertemperatur gelagert worden waren, ergab: