Search results for "LPL"
showing 10 items of 45 documents
Emotional and cognitive adjustment in abused children
1994
Research on the impact of maltreatment on children has increased in the last years, as there is a need to design appropriate treatment strategies. Social, cognitive, and emotional areas may be affected in these children. This research is aimed to study the psychological functioning of child victims, particularly in their emotional and cognitive adjustment. Nineteen children (10.3 years old) with case histories of at least 2 years of physical and emotional parental abuse and a group of 26 nonmaltreated children (9.4 years old) matched in socio-economic characteristics and coming from the same community area were compared in depressive symptomatology and attributional style by using the stand…
The role of attachment dimensions and perceived social support in predicting adjustment to cancer.
2009
Objective: Several studies carried out over the last years show that patients' adjustment is very important to the past experiences of people with cancer. In our study of 96 subjects with cancer, we examined whether patient's working model of attachment anxiety/avoidance and perceptions of social support predicts adjustment to cancer. Methods: All participants filled in a demographic questionnaire, the Relationship Scale Questionnaire (RSQ), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Mental Adjustment to Cancer (MAC). Results: Anxious attachment predicted psychological adjustment: patients with high levels of anxious attachment showed high levels of helplessness…
A translational paradigm to dtudy the rffects of uncontrollable stress in humans
2020
Theories on the aetiology of depression in humans are intimately linked to animal research on stressor controllability effects. However, explicit translations of established animal designs are lacking. In two consecutive studies, we developed a translational paradigm to study stressor controllability effects in humans. In the first study, we compared three groups of participants, one exposed to escapable stress, one yoked inescapable stress group, and a control group not exposed to stress. Although group differences indicated successful stress induction, the manipulation failed to differentiate groups according to controllability. In the second study, we employed an improved paradigm and co…
Don’t Stress, It’s Under Control: Neural Correlates of Stressor Controllability in Humans
2021
AbstractAnimal research has repeatedly shown that experience of control over an aversive event can protect against the negative consequences of later uncontrollable stress. Neurobiologically, this effect is assumed to correspond to persistent changes in the pathway linking the ventromedial prefrontal cortex (vmPFC) and the dorsal raphe nucleus. However, it remains unclear to what extent these findings translate to humans. During functional magnetic resonance imaging, we subjected participants to controllable and uncontrollable aversive but non-painful electric stimuli, as well as to a control condition without aversive stimulation. In each trial, a symbol signalled whether participants coul…
Cryptochrome-1 expression: a new prognostic marker in B-cell chronic lymphocytic leukemia
2008
Chronic lymphocytic leukemia is an adult-onset leukemia with a heterogeneous clinical behavior. When chronic lymphocytic leukemia cases were divided on the basis of IgVH mutational status, widely differing clinical courses were revealed. Since IgVH sequencing is difficult to perform in a routine diagnostic laboratory, finding a surrogate for IgVH mutational status seems an important priority. In the present study, we proposed the use of Cryptochrome- 1 as a new prognostic marker in early-stage chronic lymphocytic leukemia. Seventy patients (Binet stage A, without treatment) were included in the study. We correlated Cryptochrome-1 mRNA with well established prognostic markers such as IgVH mu…
Muzeja pamatkrājuma elektroniskais katalogs
2019
Kvalifikācijas darbā ir izstrādāts Latvijas Universitātes muzeja pamatkrājuma elektroniskais katalogs. Sākotnēji, muzeja darbinieki muzeja eksponenta uzskaiti veidoja excel formātā, kur bija apkopoti dati par priekšmetu autoriem, izmēriem, topogrāfijas novietojumiem utt.. Tomēr šie dokumenti bija tikai redzami muzeja darbiniekiem, un nebija saskarsmes ar lietotāju. Tādēļ tika nolemts, ka nepieciešams datus konvertēt uz jaunu datubāzi, kurai tiek veidota lietotāju saskarsme caur Latvijas Universitāti. Pēc sistēmu ievades, lietotāji varēs apskatīt kuri priekšmeti un kurā vietā no katra muzeja kataloga ir izlikti kā eksponenti, savukārt muzeja darbinieki ir vienīgie kuri varēs rediģēt vai piev…
Media coverage about organisations in critical situations – Analysing the impact on employees.
2013
Purpose– This research aims to investigate how critical media coverage of an organisation affects its employees. The authors expect the effects to be similar to the way media coverage about an individual would affect this person, termed “reciprocal effects”.Design/methodology/approach– Drawing on a framework for the analysis of reciprocal effects of mass media by Kepplinger and qualitative interviews among employees of 14 different organisations undergoing a crisis, the authors develop an employee-model of reciprocal effects for the context of organisational crises.Findings– This qualitative research shows that employees are affected by media coverage on a critical issue about their employe…
Entering a World with No Future: A phenomenological study describing the embodied experience of time when living with severe incurable disease
2012
This article presents findings from a phenomenological study exploring experience of time by patients living close to death. The empirical data consist of 26 open-ended interviews from 23 patients living with severe incurable disease receiving palliative care in Norway. Three aspects of experience of time were revealed as prominent: (i) Entering a world with no future; living close to death alters perception of and relationship to time. (ii) Listening to the rhythm of my body, not looking at the clock; embodied with severe illness, it is the body not the clock that structures and controls the activities of the day. (iii). Receiving time, taking time; being offered - not asked for - help is …
Willingness to Communicate in a Foreign Language: Evidence from Those Who Approach and Those Who Avoid L2 Communication
2014
It is still unclear why some learners are willing to communicate in a foreign language while others are disinclined to do so. One of the most promising paths of inquiry in this respect is the study of willingness to communicate (WTC), focusing on the volitional process of initiating, maintaining, and terminating communication. That is the reason why the main purpose of this paper is to investigate the testimonials of Polish students with persistently low or high L2 WTC scores obtained during their 3-year secondary grammar school experience. The qualitative results of the study appear to demonstrate that, independently from the individual’s general predilections towards communication in the …
Posttraumatic Stress Symptoms in Breast Cancer Patients: Temporal Evolution, Predictors, and Mediation
2014
This study (N = 102 women) evaluated the time course of posttraumatic stress symptomatology (PTSS) at different stages of nonmetastastic cancer diagnosis and treatment: during treatment, at the end of treatment, and at a 6-12 months follow-up. We also assessed the contribution of demographic, trait, and state predictors to PTSS, and coping processes as proximal mediators of the relation between Type C personality and PTSS. Results indicated that PTSS remained constant across all phases. There were significant correlations (range = .28 to .81) between PTSS and psychosocial variables and age, but not with other sociodemographic or medical factors. A linear growth curve model showed that hopel…