Search results for "LPL"
showing 10 items of 45 documents
Issues Affecting Quality of Life and Disease Burden in Lipoprotein Lipase Deficiency (Lpld) - First Step Towards a Pro Measure in Lpld
2015
Objectives: LPLD is an ultra-orphan genetic lipid disorder (prevalence 1-2/million). It is associated with severe hypertriglyceridemia and an increased risk of acute pancreatitis. Other manifestations include eruptive xanthoma, fatigue, difficulty with concentrating and cardiopulmonary symptoms. Associated symptoms, complications and the fat-restricted diet affect Quality of Life (QOL). Currently no disease-specific measure exists to assess QOL and the burden of LPLD. As part of post approval commitments of alipogene tiparvovec, regulatory bodies requested the development of a reliable measure of QOL in LPLD. This study evaluates existing EORTC questionnaires QLQ-C30 and QLQ-PAN26, and a ne…
Secondary implant stability outcome of immediate versus late placed variable-thread implants in the maxilla. A retrospective cohort study
2017
BACKGROUND The healing of xenograft augmentated intra-alveolar gaps following immediate implant placement (IMIP) after tooth extraction is likely to differ in time and density compared to the native bone part that directly contacts the implant. MATERIAL AND METHODS Secondary implant stability (SIS) data recorded 2-3 months following a late implant placement protocol (LIP) (n= 43) and 6-8 months following an immediate implant placement protocol (IMIP) (n=33) of variable-thread implants (Nobel Active™) in the maxilla were retrospectively collected from files of 63 patients (42 females, 21 males). Statistical analysis was performed using a generalized estimating equation model (GEE). Data spli…
Rīgas vēsturiskā centra telpiskās plānošanas tiesiskie aspekti
2021
Maģistra darbs “Rīgas vēsturiskā centra telpiskās plānošanas tiesiskie aspekti” ir balstīts uz autores profesionālo pieredzi jautājumos, kas saistīti ar attīstības plānošanu Rīgas vēsturiskā centra teritorijā, t.sk. teritorijas plānojuma izstrādē un tā piemērošanā, tiesību normu interpretācijā, tostarp, līdzdalību atbildes raksta sagatavošanā Satversmes tiesai tiesvedībā par pašvaldības noteikto ierobežojumu spēļu zāļu ierīkošanai atbilstību augstāka juridiskā spēka normai. Pētījuma aktualitāti pamato grozījumi Rīgas vēsturiskā centra saglabāšanas un aizsardzības likumā, normatīvā akta izmaiņas skatot valsts teritorijas attīstības plānošanas sistēmas ietvarā un kopsakarā ar uzsāktajiem attī…
Anaplastic Large T Cell Lymphoma (ALCL) is characterized by high expression of P-Selectin Glycoprotein Ligand 1 (PSGL-1) that positively correlates w…
2016
Anaplastic Large T Cell Lymphoma (ALCL) is characterized by high expression of P-Selectin Glycoprotein Ligand 1 (PSGL-1) that positively correlates with CD30 expression and TCR signaling pathway.
Parental Stress and Parental Ratings of Behavioral Problems of Enuretic Children.
2019
Background: Primary monosymptomatic nocturnal enuresis (PMNE) may have a stressful impact on the everyday life of children and parents, and it may represent a cumulative stress factor increasing feelings of "learned helplessness." Methods: The current study investigated parental stress in a group of parents (n = 330) of children affected by PMNE, compared to a group of parents (n = 330) of typical developing children (TDC). In addition, the study evaluated whether parents of PMNE children experience more emotional, social, and behavioral problems in their children, compared to parents of TDC. Finally, the study correlated frequency of enuresis with stress values and Child Behavior Checklist…
Adaptation and Initial Validation of the BRCS in an Elderly Spanish Sample
2012
Resilience is understood as a dynamic process encompassing positive adaptation within the context of adversity. This study examined the validity of the Brief Resilient Coping Scale (BRCS), a 4-item measure designed to capture tendencies to cope with stress in a highly adaptive manner, in an elderly Spanish population. A total of 133 elderly people from an association of retired persons in Valencia (Spain) provided the responses for the validation study. The factorial validity of the scale was tested using confirmatory factor analysis, with a single dimension of resilience with adequate fit indexes emerging from this analysis. The BRCS has adequate internal consistency both at the scale and…
Synthesis and structural characterization of new transition metal complexes of a highly luminescent amino-terpyridine ligand
2020
The synthesis, NMR and UV-Vis spectroscopy measurements and X-ray diffraction analysis of four new metal complexes of the amino terpyridine ligand 4́-[4-(4-aminophenyl)phenyl]-2,2́:6́,2́́-terpyridine L, namely [FeL2](ClO4)2 (1), [ZnL2](ClO4)2 (2), [CdL2](ClO4)2 (3) and [PtMe3IL] (4), are reported. The X-ray crystal structures of complexes 1-3 are 1:2 metal:ligand structures with tridentate ligands decorated around the octahedral metal centers. In complex 4, with L in a bidentate coordination mode, the Pt(IV) coordinated methyl and iodine groups form a fac-arrangement. The 1H NMR spectrum of 4 shows three 195Pt-1H resonances for the methyl groups incorporating the fac-arrangement, which conf…
Detālplānojumu izstrāde Pierīgā
2019
Maģistra darba mērķis ir izvērtēt līdzšinējo detālplānojumu izstrādes un īstenošanas praksi Pierīgā un izstrādāt priekšlikumus tā pilnveidei. Darbā vērtēti triju Pierīgas novadu: Ķekavas, Babītes un Mārupes teritorijas plānošanas dokumenti attiecībā uz detālplānojumu izstrādi, darbā pēc noteiktiem kritērijiem raksturoti un analizēti minētajās Pierīgas pašvaldībās dažādos laika posmos izstrādātie detālplānojumi un to īstenošana, un ietekme uz pašvaldību attīstību. Galvenie maģistra darba rezultāti ir darba noslēgumā sniegtie priekšlikumi detālplānošanas prakses uzlabošanai, kā arī secinājumi.
Stratēģijas iemācītās bezpalīdzības samazināšanai 8.klases angļu valodas stundās
2022
Iemācīto bezpalīdzību Seligmans un viņa kolēģi pirmo reizi aprakstīja 1967. gadā, veicot pētījumu par to, kā iepriekš šokēti suņi vēlāk nespēj izvairīties no elektriskās strāvas trieciena situācijās, kad tas bija iespējams. Kopš tā laika iemācītā bezpalīdzība ir kļuvusi par plaši atzītu teoriju psiholoģijā, un turpmākajos pētījumos ir pētīta tās saistība ar mācīšanos, socializāciju un sociālajiem aspektiem, piemēram, nabadzību un invaliditāti. Šī pētījuma mērķis bija koncentrēties uz stratēģiju izpēti iemācītās bezpalīdzības mazināšanai angļu valodas apguves klasē, fokusējoties uz 8. klases skolēniem, par izvēlētajām metodēm izmantojot gadījumu izpēti un triangulāciju, apkopojot datus no st…
How I See and Feel About Myself: Domain-Specific Self-Concept and Self-Esteem in Autistic Adults
2020
Few studies have examined the self-perceptions of autistic adults. This study aimed firstly to investigate domain-specific self-concepts and global self-esteem in autistic adults. The second aim was to examine associations between autism self-appraisals, perceived social support and global self-concept and self-esteem. The third was to determine which domains of self-concept were most closely associated with self-esteem. Participants included 71 autistic adults aged 18–70 years and 65 age, sex and education matched typically developing individuals. Participants completed an online survey of autism characteristics, global self-esteem and domain-specific self-concepts (i.e. likeability, task …